Search Results - "Camadro, Jean‐Michel"

Iron Uptake Mechanisms in Marine Phytoplankton by Sutak, Robert, Camadro, Jean-Michel, Lesuisse, Emmanuel

“…Oceanic phytoplankton species have highly efficient mechanisms of iron acquisition, as they can take up iron from environments in which it is present at…”
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AutoClassWeb: a simple web interface for Bayesian clustering of omics data by Poulain, Pierre, Camadro, Jean-Michel

“…Objective Data clustering is a common exploration step in the omics era, notably in genomics and proteomics where many genes or proteins can be quantified from…”
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The adaptive response to alternative carbon sources in the pathogen Candida albicans involves a remodeling of thiol- and glutathione-dependent redox status by Bayot, Juliette, Martin, Caroline, Chevreux, Guillaume, Camadro, Jean-Michel, Auchère, Françoise

“…Candida albicans is an opportunist pathogen responsible for a large spectrum of infections, from superficial mycosis to systemic diseases known as candidiasis…”
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Over‐expression of Dyrk1A affects bleeding by modulating plasma fibronectin and fibrinogen level in mice by Postic, Guillaume, Solarz, Jean, Loubière, Cécile, Kandiah, Janany, Sawmynaden, Jaysen, Adam, Frederic, Vilaire, Marie, Léger, Thibaut, Camadro, Jean‐Michel, Victorino, Daniella Balduino, Potier, Marie‐Claude, Bun, Eric, Moroy, Gautier, Kauskot, Alexandre, Christophe, Olivier, Janel, Nathalie

“…Down syndrome is the most common chromosomal abnormality in humans. Patients with Down syndrome have hematologic disorders, including mild to moderate…”
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N‐homocysteinylation of tau and MAP1 is increased in autopsy specimens of Alzheimer's disease and vascular dementia by Bossenmeyer‐Pourié, Carine, Smith, A David, Lehmann, Sylvain, Deramecourt, Vincent, Sablonnière, Bernard, Camadro, Jean‐Michel, Pourié, Grégory, Kerek, Racha, Helle, Deborah, Umoret, Remy, Guéant‐Rodriguez, Rosa‐Maria, Rigau, Valérie, Gabelle, Audrey, Sequeira, Jeffrey M, Quadros, Edward V, Daval, Jean‐Luc, Guéant, Jean‐Louis

“…The pathomechanisms that associate a deficit in folate and/or vitamin B12 and the subsequent hyperhomocysteinemia with pathological brain ageing are unclear…”
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Imaging mass spectrometry reveals modified forms of histone H4 as new biomarkers of microvascular invasion in hepatocellular carcinomas by Poté, Nicolas, Alexandrov, Theodore, Le Faouder, Julie, Laouirem, Samira, Léger, Thibaut, Mebarki, Mouniya, Belghiti, Jacques, Camadro, Jean‐Michel, Bedossa, Pierre, Paradis, Valérie

“…Microvascular invasion (MiVI) is a major risk factor in postoperative tumor recurrence and mortality in hepatocellular carcinoma (HCC). Unfortunately, this…”
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LGP2 binds to PACT to regulate RIG-I- and MDA5-mediated antiviral responses by Sanchez David, Raul Y, Combredet, Chantal, Najburg, Valérie, Millot, Gael A, Beauclair, Guillaume, Schwikowski, Benno, Léger, Thibaut, Camadro, Jean-Michel, Jacob, Yves, Bellalou, Jacques, Jouvenet, Nolwenn, Tangy, Frédéric, Komarova, Anastassia V

“…The retinoic acid-inducible gene I (RIG-I)-like receptors (RLRs) RIG-I, MDA5, and LGP2 stimulate inflammatory and antiviral responses by sensing nonself RNA…”
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Dysfunction of mitochondrial Lon protease and identification of oxidized protein in mouse brain following exposure to MPTP: Implications for Parkinson disease by Bulteau, Anne-Laure, Mena, Natalia P., Auchère, Françoise, Lee, Irene, Prigent, Annick, Lobsiger, Christian S., Camadro, Jean-Michel, Hirsch, Etienne C.

“…Compelling evidence suggests that mitochondrial dysfunction leading to reactive oxygen species (ROS) production and protein oxidation could represent a…”
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Friedreich ataxia: molecular mechanisms, redox considerations, and therapeutic opportunities by Santos, Renata, Lefevre, Sophie, Sliwa, Dominika, Seguin, Alexandra, Camadro, Jean-Michel, Lesuisse, Emmanuel

“…Mitochondrial dysfunction and oxidative damage are at the origin of numerous neurodegenerative diseases like Friedreich ataxia and Alzheimer and Parkinson…”
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A Simple Light Isotope Metabolic Labeling (SLIM-labeling) Strategy: A Powerful Tool to Address the Dynamics of Proteome Variations In Vivo by Léger, Thibaut, Garcia, Camille, Collomb, Laetitia, Camadro, Jean-Michel

“…Many quantitative proteomics strategies rely on in vivo metabolic incorporation of amino acids with modified stable isotope profiles into proteins. These…”
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Proteomics profiling of urine reveals specific titin fragments as biomarkers of Duchenne muscular dystrophy by Rouillon, Jeremy, Zocevic, Aleksandar, Leger, Thibaut, Garcia, Camille, Camadro, Jean-Michel, Udd, Bjarne, Wong, Brenda, Servais, Laurent, Voit, Thomas, Svinartchouk, Fedor

“…Abstract Diagnosis of muscular dystrophies is currently based on invasive methods requiring muscle biopsies or blood tests. The aim of the present study was to…”
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Homocysteinylation of neuronal proteins contributes to folate deficiency‐associated alterations of differentiation, vesicular transport, and plasticity in hippocampal neuronal cells by Akchiche, Nassila, Bossenmeyer‐Pourié, Carine, Kerek, Racha, Martin, Nicolas, Pourié, Grégory, Koziel, Violette, Helle, Déborah, Alberto, Jean‐Marc, Ortiou, Sandrine, Camadro, Jean‐Michel, Léger, Thibaut, Guéant, Jean‐Louis, Daval, Jean‐Luc

“…Despite the key role in neuronal development of a deficit in the methyl donor folate, little is known on the underlying mechanisms. We therefore studied the…”
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Serum proteomic profiling reveals fragments of MYOM3 as potential biomarkers for monitoring the outcome of therapeutic interventions in muscular dystrophies by Rouillon, Jérémy, Poupiot, Jérôme, Zocevic, Aleksandar, Amor, Fatima, Léger, Thibaut, Garcia, Camille, Camadro, Jean-Michel, Wong, Brenda, Pinilla, Robin, Cosette, Jérémie, Coenen-Stass, Anna M L, Mcclorey, Graham, Roberts, Thomas C, Wood, Matthew J A, Servais, Laurent, Udd, Bjarne, Voit, Thomas, Richard, Isabelle, Svinartchouk, Fedor

“…Therapy-responsive biomarkers are an important and unmet need in the muscular dystrophy field where new treatments are currently in clinical trials. By using a…”
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A Comparative Study of Iron Uptake Mechanisms in Marine Microalgae: Iron Binding at the Cell Surface Is a Critical Step by Sutak, Robert, Botebol, Hugo, Blaiseau, Pierre-Louis, Léger, Thibaut, Bouget, François-Yves, Camadro, Jean-Michel, Lesuisse, Emmanuel

“…We investigated iron uptake mechanisms in five marine microalgae from different ecologically important phyla: the diatoms Phaeodactylum tricornutum and…”
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Novel Insights into Redox-Based Mechanisms for Auranofin-Induced Rapid Cancer Cell Death by Hatem, Elie, El Banna, Nadine, Heneman-Masurel, Amélie, Baïlle, Dorothée, Vernis, Laurence, Riquier, Sylvie, Golinelli-Cohen, Marie-Pierre, Guittet, Olivier, Vallières, Cindy, Camadro, Jean-Michel, Qiu, Xue, Hildebrandt, Niko, Lepoivre, Michel, Huang, Meng-Er

“…Auranofin (Ridaura®, AUF) is a gold complex originally approved as an antirheumatic agent that has emerged as a potential candidate for multiple repurposed…”
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The adaptive response to iron involves changes in energetic strategies in the pathogen Candida albicans by Duval, Celia, Macabiou, Carole, Garcia, Camille, Lesuisse, Emmanuel, Camadro, Jean‐Michel, Auchère, Françoise

“…Candida albicans is an opportunist pathogen responsible for a large spectrum of infections, from superficial mycosis to systemic diseases known as candidiasis…”
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Endocytosis-mediated siderophore uptake as a strategy for Fe acquisition in diatoms by Kazamia, Elena, Sutak, Robert, Paz-Yepes, Javier, Dorrell, Richard G, Vieira, Fabio Rocha Jimenez, Mach, Jan, Morrissey, Joe, Leon, Sébastien, Lam, France, Pelletier, Eric, Camadro, Jean-Michel, Bowler, Chris, Lesuisse, Emmanuel

“…Phytoplankton growth is limited in vast oceanic regions by the low bioavailability of iron. Iron fertilization often results in diatom blooms, yet the…”
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Additional insights into the organization of transcriptional regulatory modules based on a 3D model of the Saccharomyces cerevisiae genome by Poinsignon, Thibault, Gallopin, Mélina, Camadro, Jean-Michel, Poulain, Pierre, Lelandais, Gaëlle

“…Transcriptional regulatory modules are usually modelled via a network, in which nodes correspond to genes and edges correspond to regulatory associations…”
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Central role for ferritin in the day/night regulation of iron homeostasis in marine phytoplankton by Botebol, Hugo, Lesuisse, Emmanuel, Šuták, Robert, Six, Christophe, Lozano, Jean-Claude, Schatt, Philippe, Vergé, Valérie, Kirilovsky, Amos, Morrissey, Joe, Léger, Thibaut, Camadro, Jean-Michel, Gueneugues, Audrey, Bowler, Chris, Blain, Stéphane, Bouget, François-Yves

“…In large regions of the open ocean, iron is a limiting resource for phytoplankton. The reduction of iron quota and the recycling of internal iron pools are…”
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Redox modifications of cysteine-containing proteins, cell cycle arrest and translation inhibition: Involvement in vitamin C-induced breast cancer cell death by El Banna, Nadine, Hatem, Elie, Heneman-Masurel, Amélie, Léger, Thibaut, Baïlle, Dorothée, Vernis, Laurence, Garcia, Camille, Martineau, Sylvain, Dupuy, Corinne, Vagner, Stéphan, Camadro, Jean-Michel, Huang, Meng-Er

“…Vitamin C (VitC) possesses pro-oxidant properties at high pharmacologic concentrations which favor repurposing VitC as an anti-cancer therapeutic agent…”
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