Search Results - "Camacho, Cristina"
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Emerging roles of MT‐MMPs in embryonic development
Published in Developmental dynamics (01-02-2022)“…Membrane‐type matrix metalloproteinases (MT‐MMPs) are cell membrane‐tethered proteinases that belong to the family of the MMPs. Apart from their roles in…”
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The intestinal barrier function and its involvement in digestive disease
Published in Revista española de enfermedades digestivas (01-11-2015)“…The gastrointestinal mucosal surface is lined with epithelial cells representing an effective barrier made up with intercellular junctions that separate the…”
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Emerging mechanisms in morphogen-mediated axon guidance
Published in BioEssays (01-10-2009)“…Early in animal development, gradients of secreted morphogenic molecules, such as Sonic hedgehog (Shh), Wnt and TGFβ/Bmp family members, regulate cell…”
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Polyploidy and hybridization in the Mediterranean: unravelling the evolutionary history of Centaurium (Gentianaceae)
Published in Annals of botany (09-07-2024)“…Polyploidy is considered one of the main mechanisms of plant evolution and speciation. In the Mediterranean basin, polyploidy has contributed to making this…”
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Phylogenetic, cytogenetic and morphological evidences are critical for recognizing a new genus: Valdesiana, an Iberian intergeneric allopolyploid between Schenkia and Exaculum
Published in Plant systematics and evolution (01-08-2023)“…The present taxonomic status of Schenkia elegans , endemism recently described in the Iberian Peninsula, and its relationship with the sympatric and the…”
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Autonomous and non-autonomous Shh signalling mediate the in vivo growth and guidance of mouse retinal ganglion cell axons
Published in Development (Cambridge) (01-11-2008)“…In non-mammalian vertebrates, the relatively homogeneous population of retinal ganglion cells (RGCs) differentiates and projects entirely to the contralateral…”
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Polyploidy Expands the Range of Centaurium (Gentianaceae)
Published in Frontiers in plant science (10-03-2021)“…The Mediterranean region is one of the most important worldwide hotspots in terms of number of species and endemism, and multiple hypotheses have been proposed…”
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Molecular Mechanisms Driven by MT4-MMP in Cancer Progression
Published in International journal of molecular sciences (09-06-2023)“…MT4-MMP (or MMP-17) belongs to the membrane-type matrix metalloproteinases (MT-MMPs), a distinct subset of the MMP family that is anchored to the cell surface,…”
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Mucosal pathobiology and molecular signature of epithelial barrier dysfunction in the small intestine in irritable bowel syndrome
Published in Journal of gastroenterology and hepatology (01-01-2017)“…Irritable bowel syndrome (IBS) is one of the most prevalent gastrointestinal disorders in developed countries. Its etiology remains unknown; however, a common…”
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The interplay between climatic niche evolution, polyploidy and reproductive traits explains plant speciation in the Mediterranean Basin: a case study in Centaurium (Gentianaceae)
Published in Frontiers in plant science (09-08-2024)“…Speciation and diversification patterns in angiosperms are frequently shaped by niche evolution. Hill is a Mediterranean genus with ca. 25 species, of which…”
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Deficiency of MMP17/MT4-MMP Proteolytic Activity Predisposes to Aortic Aneurysm in Mice
Published in Circulation research (03-07-2015)“…RATIONALE:Aortic dissection or rupture resulting from aneurysm causes 1% to 2% of deaths in developed countries. These disorders are associated with mutations…”
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Cdon acts as a Hedgehog decoy receptor during proximal-distal patterning of the optic vesicle
Published in Nature communications (08-07-2014)“…Patterning of the vertebrate optic vesicle into proximal/optic stalk and distal/neural retina involves midline-derived Hedgehog (Hh) signalling, which promotes…”
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Developmental expression of membrane type 4-matrix metalloproteinase (Mt4-mmp/Mmp17) in the mouse embryo
Published in PloS one (19-09-2017)“…Matrix metalloproteinases (MMPs) constitute a large group of endoproteases that play important functions during embryonic development, tumor metastasis and…”
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Low lung function in Bipolar Disorder and Schizophrenia: a hidden risk
Published in Frontiers in physiology (2024)“…People with serious mental illness (SMI), such as schizophrenia and bipolar disorder, have a higher risk of premature morbidity and mortality. In the general…”
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Spanish HCMV Seroprevalence in the 21st Century
Published in Viruses (19-12-2023)“…Human cytomegalovirus (HCMV) is linked to age-related diseases like cardiovascular disease, neurodegenerative conditions, and cancer. It can also cause…”
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Isolation and characterization of microsatellites markers in Centaurium grandiflorum ssp. boissieri
Published in Molecular biology reports (01-12-2021)“…Background Estimating outcrossing/selfing rates and characterizing genetic diversity with microsatellite markers are crucial to understanding the evolution of…”
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Evolution of reproductive traits and selfing syndrome in the sub-endemic Mediterranean genus Centaurium Hill (Gentianaceae)
Published in Botanical journal of the Linnean Society (24-09-2019)“…Abstract In flowering plants, the shift from outcrossing to selfing is associated with a set of correlated changes in morphological and reproductive features…”
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Shh/Boc signaling is required for sustained generation of ipsilateral projecting ganglion cells in the mouse retina
Published in The Journal of neuroscience (15-05-2013)“…Sonic Hedgehog (Shh) signaling is an important determinant of vertebrate retinal ganglion cell (RGC) development. In mice, there are two major RGC populations:…”
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Dynamic Expression of Membrane Type 1-Matrix Metalloproteinase (Mt1-mmp/Mmp14) in the Mouse Embryo
Published in Cells (Basel, Switzerland) (17-09-2021)“…MT1-MMP/MMP14 belongs to a subgroup of the matrix metalloproteinases family that presents a transmembrane domain, with a cytosolic tail and the catalytic site…”
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Appropriate Bmp7 levels are required for the differentiation of midline guidepost cells involved in corpus callosum formation
Published in Developmental neurobiology (Hoboken, N.J.) (01-05-2011)“…Guidepost cells are essential structures for the establishment of major axonal tracts. How these structures are specified and acquire their axon guidance…”
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