How Anesthetic, Analgesic and Other Non-Surgical Techniques During Cancer Surgery Might Affect Postoperative Oncologic Outcomes: A Summary of Current State of Evidence

The question of whether anesthetic, analgesic or other perioperative intervention during cancer resection surgery might influence long-term oncologic outcomes has generated much attention over the past 13 years. A wealth of experimental and observational clinical data have been published, but the re...

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Published in:Cancers Vol. 11; no. 5; p. 592
Main Authors: Forget, Patrice, Aguirre, Jose A, Bencic, Ivanka, Borgeat, Alain, Cama, Allessandro, Condron, Claire, Eintrei, Christina, Eroles, Pilar, Gupta, Anil, Hales, Tim G, Ionescu, Daniela, Johnson, Mark, Kabata, Pawel, Kirac, Iva, Ma, Daqing, Mokini, Zhirajr, Guerrero Orriach, Jose Luis, Retsky, Michael, Sandrucci, Sergio, Siekmann, Wiebke, Štefančić, Ljilja, Votta-Vellis, Gina, Connolly, Cara, Buggy, Donal
Format: Journal Article
Language:English
Published: Switzerland MDPI AG 2019
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Summary:The question of whether anesthetic, analgesic or other perioperative intervention during cancer resection surgery might influence long-term oncologic outcomes has generated much attention over the past 13 years. A wealth of experimental and observational clinical data have been published, but the results of prospective, randomized clinical trials are awaited. The European Union supports a pan-European network of researchers, clinicians and industry partners engaged in this question (COST Action 15204: Euro-Periscope). In this narrative review, members of the Euro-Periscope network briefly summarize the current state of evidence pertaining to the potential effects of the most commonly deployed anesthetic and analgesic techniques and other non-surgical interventions during cancer resection surgery on tumor recurrence or metastasis.
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All of the authors are the members of EU COST ACTION 15204 EuroPeriscope.
ISSN:2072-6694
2072-6694
DOI:10.3390/cancers11050592