Search Results - "Calzada, María José"
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Antiretroviral therapy duration and immunometabolic state determine efficacy of ex vivo dendritic cell-based treatment restoring functional HIV-specific CD8+ T cells in people living with HIV
Published in EBioMedicine (01-07-2022)“…Dysfunction of CD8+ T cells in people living with HIV-1 (PLWH) receiving anti-retroviral therapy (ART) has restricted the efficacy of dendritic cell (DC)-based…”
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Hypoxia negatively regulates antimetastatic PEDF in melanoma cells by a hypoxia inducible factor-independent, autophagy dependent mechanism
Published in PloS one (23-03-2012)“…Pigment epithelium-derived factor (PEDF), a member of the serine protease inhibitor (SERPIN) superfamily, displays a potent antiangiogenic and antimetastatic…”
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15-Deoxy-Δ¹²,¹⁴-prostaglandin-J₂ reveals a new pVHL-independent, lysosomal-dependent mechanism of HIF-1α degradation
Published in Cellular and molecular life sciences : CMLS (01-07-2009)“…Hypoxia-inducible factor-1α (HIF-1α) protein is degraded under normoxia by its association to von Hippel-Lindau protein (pVHL) and further proteasomal…”
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4
Time‐dependent dual effect of NLRP3 inflammasome in brain ischaemia
Published in British journal of pharmacology (01-04-2022)“…Background Inflammasomes are cytosolic multiprotein complexes which, upon assembly, activate the maturation and secretion of the inflammatory cytokines IL‐1β…”
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NFκB and NLRP3/NLRC4 inflammasomes regulate differentiation, activation and functional properties of monocytes in response to distinct SARS-CoV-2 proteins
Published in Nature communications (07-03-2024)“…Increased recruitment of transitional and non-classical monocytes in the lung during SARS-CoV-2 infection is associated with COVID-19 severity. However,…”
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15-Deoxy-[Delta]12,14-prostaglandin-J2 reveals a new pVHL-independent, lysosomal-dependent mechanism of HIF-1[alpha] degradation
Published in Cellular and molecular life sciences : CMLS (01-07-2009)“…Hypoxia-inducible factor-1α (HIF-1α) protein is degraded under normoxia by its association to von Hippel-Lindau protein (pVHL) and further proteasomal…”
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7
Deregulated cellular circuits driving immunoglobulins and complement consumption associate with the severity of COVID‐19 patients
Published in European journal of immunology (01-03-2021)“…SARS‐CoV‐2 infection causes an abrupt response by the host immune system, which is largely responsible for the outcome of COVID‐19. We investigated whether the…”
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15-Deoxy-Delta(12,14)-prostaglandin-J(2) reveals a new pVHL-independent, lysosomal-dependent mechanism of HIF-1alpha degradation
Published in Cellular and molecular life sciences : CMLS (01-07-2009)“…Hypoxia-inducible factor-1alpha (HIF-1alpha) protein is degraded under normoxia by its association to von Hippel-Lindau protein (pVHL) and further proteasomal…”
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Functional characterization of GPIIb- and GPIIIa-specific monoclonal antibodies. Further evidence for the existence of agonist-specific activated states of the platelet fibrinogen receptor
Published in Platelets (Edinburgh) (1997)“…In this work human platelet aggregation induced in vitro by ADP, collagen, arachidonic acid and U-46619 (a thromboxane A analogue) was used as a functional…”
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