Search Results - "Calmiano, Mark"

Discovery of 4-azaindoles as novel inhibitors of c-Met kinase by Porter, John, Lumb, Simon, Franklin, Richard J., Gascon-Simorte, Jose M., Calmiano, Mark, Riche, Kelly Le, Lallemand, Bénédicte, Keyaerts, Jean, Edwards, Helen, Maloney, Alison, Delgado, Jean, King, Lloyd, Foley, Anne, Lecomte, Fabien, Reuberson, James, Meier, Christoph, Batchelor, Mark

“…The SAR and X-ray crystal structure of a series of 4-azaindole inhibitors of c-Met kinase is reported. A series of 4-azaindole inhibitors of c-Met kinase is…”
Get full text

Structure-based virtual screening for novel ligands by Pitt, William R, Calmiano, Mark D, Kroeplien, Boris, Taylor, Richard D, Turner, James P, King, Michael A

“…Computational searches for novel ligands for a given protein binding site have become ubiquitous in the pharmaceutical industry, and are potentially equally…”
Get more information

A white-knuckle ride of open COVID drug discovery by von Delft, Frank, Calmiano, Mark, Chodera, John, Griffen, Ed, Lee, Alpha, London, Nir, Matviuk, Tatiana, Perry, Ben, Robinson, Matt, von Delft, Annette

“…In early 2020, a spontaneous global collaboration came together to design a new, urgent antiviral treatment. There are lessons in what happened next. In early…”
Get full text

Natural Conformational Sampling of Human TNFα Visualized by Double Electron-Electron Resonance by Carrington, Bruce, Myers, William K., Horanyi, Peter, Calmiano, Mark, Lawson, Alastair D.G.

“…Double electron-electron resonance in conjunction with site-directed spin labeling has been used to probe natural conformational sampling of the human tumor…”
Get full text

Discovery of a Potent, Orally Bioavailable PI4KIIIβ Inhibitor (UCB9608) Able To Significantly Prolong Allogeneic Organ Engraftment in Vivo by Reuberson, James, Horsley, Helen, Franklin, Richard J, Ford, Daniel, Neuss, Judi, Brookings, Daniel, Huang, Qiuya, Vanderhoydonck, Bart, Gao, Ling-Jie, Jang, Mi-Yeon, Herdewijn, Piet, Ghawalkar, Anant, Fallah-Arani, Farnaz, Khan, Adnan R, Henshall, Jamie, Jairaj, Mark, Malcolm, Sarah, Ward, Eleanor, Shuttleworth, Lindsay, Lin, Yuan, Li, Shengqiao, Louat, Thierry, Waer, Mark, Herman, Jean, Payne, Andrew, Ceska, Tom, Doyle, Carl, Pitt, Will, Calmiano, Mark, Augustin, Martin, Steinbacher, Stefan, Lammens, Alfred, Allen, Rodger

“…The primary target of a novel series of immuno­suppressive 7-piperazin-1-yl­thiazolo­[5,4-d]­pyrimidin-5-amines was identified as the lipid kinase, PI4KIIIβ…”
Get full text

Discovery of a novel series of quinoxalines as inhibitors of c-Met kinase by Porter, John, Lumb, Simon, Lecomte, Fabien, Reuberson, James, Foley, Anne, Calmiano, Mark, le Riche, Kelly, Edwards, Helen, Delgado, Jean, Franklin, Richard J., Gascon-Simorte, Jose M., Maloney, Alison, Meier, Christoph, Batchelor, Mark

“…The SAR of a series of quinoxaline inhibitors of c-Met kinase is reported. A series of quinoxaline inhibitors of c-Met kinase is described. The postulated…”
Get full text

Computer simulation of molecular sorption in zeolites by Calmiano, Mark Daniel

“…The work presented in this thesis encompasses the computer simulation of molecular sorption. In Chapter 1 we outline the aims and objectives of this work…”
Get full text