Gadolinium-based contrast agents for magnetic resonance imaging

Gadolinium-based contrast agents are increasingly being used in magnetic resonance imaging. These agents can improve the contrast in images and provide information about function and metabolism, increasing both sensitivity and specificity. We describe the gadolinium-based contrast agents that have b...

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Bibliographic Details
Published in:	Radiologia Vol. 56 Suppl 1; p. 21
Main Authors:	Carrasco Muñoz, S, Calles Blanco, C, Marcin, Javier, Fernández Álvarez, C, Lafuente Martínez, J
Format:	Journal Article
Language:	Spanish
Published:	Spain 01-06-2014
Subjects:	Contrast Media - adverse effects Gadolinium Humans Kidney Diseases - chemically induced Kidney Diseases - prevention & control Magnetic Resonance Imaging - methods Nephrogenic Fibrosing Dermopathy - chemically induced Nephrogenic Fibrosing Dermopathy - prevention & control Risk Factors Resonancia magnética Gadolinium Gadolinio Magnetic resonance imaging Contrastes Contrasts
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Summary:	Gadolinium-based contrast agents are increasingly being used in magnetic resonance imaging. These agents can improve the contrast in images and provide information about function and metabolism, increasing both sensitivity and specificity. We describe the gadolinium-based contrast agents that have been approved for clinical use, detailing their main characteristics based on their chemical structure, stability, and safety. In general terms, these compounds are safe. Nevertheless, adverse reactions, the possibility of nephrotoxicity from these compounds, and the possibility of developing nephrogenic systemic fibrosis will be covered in this article. Lastly, the article will discuss the current guidelines, recommendations, and contraindications for their clinical use, including the management of pregnant and breast-feeding patients.
ISSN:	1578-178X
DOI:	10.1016/j.rx.2014.06.005