Search Results - "Callanan, Mary"

BET Family Protein BRD4: An Emerging Actor in NFκB Signaling in Inflammation and Cancer by Hajmirza, Azadeh, Emadali, Anouk, Gauthier, Arnaud, Casasnovas, Olivier, Gressin, Rémy, Callanan, Mary B

“…NFκB (Nuclear Factor- -light-chain-enhancer of activated B cells) signaling elicits global transcriptional changes by activating cognate promoters and through…”
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Ibrutinib, obinutuzumab, and venetoclax in relapsed and untreated patients with mantle cell lymphoma: a phase 1/2 trial by Le Gouill, Steven, Morschhauser, Franck, Chiron, David, Bouabdallah, Krimo, Cartron, Guillaume, Casasnovas, Olivier, Bodet-Milin, Caroline, Ragot, Sylviane, Bossard, Céline, Nadal, Nathalie, Herbaux, Charles, Tessoulin, Benoit, Tchernonog, Emmanuelle, Rossi, Cédric, McCulloch, Rory, Gastinne, Thomas, Callanan, Mary B., Rule, Simon

“…[Display omitted] Ibrutinib, obinutuzumab, and venetoclax demonstrate synergy in preclinical models of mantle cell lymphoma (MCL). OAsIs (NCT02558816), a…”
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MEK inhibition overcomes chemoimmunotherapy resistance by inducing CXCL10 in cancer cells by Limagne, Emeric, Nuttin, Lisa, Thibaudin, Marion, Jacquin, Elise, Aucagne, Romain, Bon, Marjorie, Revy, Solène, Barnestein, Robby, Ballot, Elise, Truntzer, Caroline, Derangère, Valentin, Fumet, Jean-David, Latour, Charlène, Rébé, Cédric, Bellaye, Pierre-Simon, Kaderbhaï, Coureche-Guillaume, Spill, Aodrenn, Collin, Bertrand, Callanan, Mary B., Lagrange, Aurélie, Favier, Laure, Coudert, Bruno, Arnould, Laurent, Ladoire, Sylvain, Routy, Bertrand, Joubert, Philippe, Ghiringhelli, François

“…Chemotherapy with anti PD-1/PD-L1 antibodies has become the standard of care for patients with metastatic non-small cell lung cancer (mNSCLC). Using lung tumor…”
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The histone H4 Lys 20 methyltransferase PR-Set7 regulates replication origins in mammalian cells by Sardet, Claude, Julien, Eric, Tardat, Mathieu, Brustel, Julien, Kirsh, Olivier, Lefevbre, Christine, Callanan, Mary

“…The initiation of DNA synthesis is governed by the licensing of replication origins, which consists of assembling a pre-replication complex (pre-RC) on origins…”
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CXCL-8/IL8 Produced by Diffuse Large B-cell Lymphomas Recruits Neutrophils Expressing a Proliferation-Inducing Ligand APRIL by Manfroi, Benoit, McKee, Thomas, Mayol, Jean Francois, Tabruyn, Sebastien, Moret, Sebastien, Villiers, Christian, Righini, Christian, Dyer, Martin, Callanan, Mary, Schneider, Pascal, Tzankov, Alexandar, Matthes, Thomas, Sturm, Nathalie, Huard, Bertrand

“…Tumor-infiltrating neutrophils have been implicated in malignant development and progression, but mechanisms are ill defined. Neutrophils produce a…”
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The secret message of heterochromatin: new insights into the mechanisms and function of centromeric and pericentric repeat sequence transcription by Eymery, Angeline, Callanan, Mary, Vourc'h, Claire

“…In the fission yeast, S. Pombe, small dsRNA generated by RNAi-dependent mechanisms are involved in the establishment and maintenance of heterochromatic…”
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Integrative Clinical and DNA Methylation Analyses in a Population-Based Cohort Identifies CDH17 and LRP2 as Risk Recurrence Factors in Stage II Colon Cancer by Tournier, Benjamin, Aucagne, Romain, Truntzer, Caroline, Fournier, Cyril, Ghiringhelli, François, Chapusot, Caroline, Martin, Laurent, Bouvier, Anne Marie, Manfredi, Sylvain, Jooste, Valérie, Callanan, Mary B, Lepage, Côme

“…Stage II colon cancer (CC), although diagnosed early, accounts for 16% of CC deaths. Predictors of recurrence risk could mitigate this but are currently…”
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transcriptomic analysis of human centromeric and pericentric sequences in normal and tumor cells by Eymery, Angéline, Horard, Béatrice, Atifi-Borel, Michèle El, Fourel, Geneviève, Berger, François, Vitte, Anne-Laure, Van den Broeck, Arnaud, Brambilla, Elisabeth, Fournier, Alexandra, Callanan, Mary, Gazzeri, Sylvie, Khochbin, Saadi, Rousseaux, Sophie, Gilson, Eric, Vourc'h, Claire

“…Although there is now evidence that the expression of centromeric (CT) and pericentric (PCT) sequences are key players in major genomic functions, their…”
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Identification of a novel BET bromodomain inhibitor‐sensitive, gene regulatory circuit that controls Rituximab response and tumour growth in aggressive lymphoid cancers by Emadali, Anouk, Rousseaux, Sophie, Bruder‐Costa, Juliana, Rome, Claire, Duley, Samuel, Hamaidia, Sieme, Betton, Patricia, Debernardi, Alexandra, Leroux, Dominique, Bernay, Benoit, Kieffer‐Jaquinod, Sylvie, Combes, Florence, Ferri, Elena, McKenna, Charles E., Petosa, Carlo, Bruley, Christophe, Garin, Jérôme, Ferro, Myriam, Gressin, Rémy, Callanan, Mary B., Khochbin, Saadi

“…Immuno‐chemotherapy elicit high response rates in B‐cell non‐Hodgkin lymphoma but heterogeneity in response duration is observed, with some patients achieving…”
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Repeat Element Activation-Driven Inflammation: Role of NFκB and Implications in Normal Development and Cancer? by Dumetier, Baptiste, Sauter, Camille, Hajmirza, Azadeh, Pernon, Baptiste, Aucagne, Romain, Fournier, Cyril, Row, Céline, Guidez, Fabien, Rossi, Cédric, Lepage, Côme, Delva, Laurent, Callanan, Mary B

“…The human genome is composed of unique DNA sequences that encode proteins and unique sequence noncoding RNAs that are essential for normal development and…”
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Identification of an alternative CD20 transcript variant in B-cell malignancies coding for a novel protein associated to rituximab resistance by Henry, Carole, Deschamps, Marina, Rohrlich, Pierre-Simon, Pallandre, Jean-René, Rémy-Martin, Jean-Paul, Callanan, Mary, Traverse-Glehen, Alexandra, GrandClément, Camille, Garnache-Ottou, Francine, Gressin, Remy, Deconinck, Eric, Salles, Gilles, Robinet, Eric, Tiberghien, Pierre, Borg, Christophe, Ferrand, Christophe

“…Human CD20 is a B-cell lineage–specific marker expressed by normal and leukemic B cells from the pre-B to the plasma-cell stages and is a target for rituximab…”
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Telomeric damage in early stage of chronic lymphocytic leukemia correlates with shelterin dysregulation by Augereau, Adeline, T'kint de Roodenbeke, Claire, Simonet, Thomas, Bauwens, Serge, Horard, Béatrice, Callanan, Mary, Leroux, Dominique, Jallades, Laurent, Salles, Gilles, Gilson, Eric, Poncet, Delphine

“…Cells of B-cell chronic lymphocytic leukemia (B-CLL) are characterized by short telomeres despite a low proliferative index. Because telomere length has been…”
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CYCLON and NPM1 Cooperate within an Oncogenic Network Predictive of R-CHOP Response in DLBCL by Bouroumeau, Antonin, Bussot, Lucile, Hamaidia, Sieme, Garcìa-Sandoval, Andrea, Bergan-Dahl, Anna, Betton-Fraisse, Patricia, Duley, Samuel, Fournier, Cyril, Aucagne, Romain, Adrait, Annie, Couté, Yohann, McLeer, Anne, Col, Edwige, David-Boudet, Laurence, Raskovalova, Tatiana, Jacob, Marie-Christine, Vettier, Claire, Chevalier, Simon, Carras, Sylvain, Lefebvre, Christine, Algrin, Caroline, Gressin, Rémy, Callanan, Mary B., Sartelet, Hervé, Bonnefoix, Thierry, Emadali, Anouk

“…R-CHOP immuno-chemotherapy significantly improved clinical management of diffuse large B-cell lymphoma (DLBCL). However, 30–40% of DLBCL patients still present…”
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A six gene expression signature defines aggressive subtypes and predicts outcome in childhood and adult acute lymphoblastic leukemia by Wang, Jin, Mi, Jian-Qing, Debernardi, Alexandra, Vitte, Anne-Laure, Emadali, Anouk, Meyer, Julia A, Charmpi, Konstantina, Ycart, Bernard, Callanan, Mary B, Carroll, William L, Khochbin, Saadi, Rousseaux, Sophie

“…Abnormal gene expression in cancer represents an under-explored source of cancer markers and therapeutic targets. In order to identify gene expression…”
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Droplet Digital PCR Quantification of Mantle Cell Lymphoma Follow‐up Samples From Four Prospective Trials of the European MCL Network by Drandi, Daniela, Alcantara, Marion, Benmaad, Ichrafe, Söhlbrandt, Arian, Lhermitte, Ludovic, Zaccaria, GianMaria, Ferrante, Martina, Genuardi, Elisa, Mantoan, Barbara, Villarese, Patrick, Cheminant, Morgane, Starza, Irene della, Ciabatti, Elena, Bomben, Riccardo, Jimenez, Cristina, Callanan, Mary, Abdo, Chrystelle, Eckert, Cornelia, Ribrag, Vincent, Cortelazzo, Sergio, Dreyling, Martin, Hermine, Olivier, Delfau‐Larue, Marie‐Hélène, Pott, Christiane, Ladetto, Marco, Ferrero, Simone, Macintyre, Elizabeth

“…Supplemental Digital Content is available in the text Minimal residual disease (MRD) has been increasingly investigated in mantle cell lymphoma (MCL),…”
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Protein arginine methyltransferase 2 controls inflammatory signaling in acute myeloid leukemia by Sauter, Camille, Morin, Thomas, Guidez, Fabien, Simonet, John, Fournier, Cyril, Row, Céline, Masnikov, Denis, Pernon, Baptiste, Largeot, Anne, Aznague, Aziza, Hérault, Yann, Sauvageau, Guy, Maynadié, Marc, Callanan, Mary, Bastie, Jean-Noël, Aucagne, Romain, Delva, Laurent

“…Arginine methylation is catalyzed by protein arginine methyltransferases (PRMTs) and is involved in various cellular processes, including cancer development…”
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c‐MYC and p53 expression highlight starry‐sky pattern as a favourable prognostic feature in R‐CHOP‐treated diffuse large B‐cell lymphoma by Bouroumeau, Antonin, Bussot, Lucile, Bonnefoix, Thierry, Fournier, Cyril, Chapusot, Caroline, Casasnovas, Olivier, Martin, Laurent, McLeer, Anne, Col, Edwige, David‐Boudet, Laurence, Lefebvre, Christine, Algrin, Caroline, Raskovalova, Tatiana, Jacob, Marie‐Christine, Vettier, Claire, Chevalier, Simon, Callanan, Mary B, Gressin, Rémy, Emadali, Anouk, Sartelet, Hervé

“…Diffuse large B‐cell lymphoma (DLBCL) is a clinically heterogeneous entity, in which the first‐line treatment currently consists of an immuno‐chemotherapy…”
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P1090: LONG TERM FOLLOW‐UP OF UNTREATED/RELAPSING MCL PATIENTS WITH THE IBRUTINIB, OBINUTUZUMAB, AND VENETOCLAX COMBINATION by Le Gouill, Steven, Morschhauser, Franck, Chiron, David, Bouabdallah, Kamal, Cartron, Guillaume, Olivier Casasnovas, Rene, Milin, Caroline, Herbaux, Charles, Tchernonog, Emmanuelle, Rossi, Cedric, Rule, Simon, Gastinne, Thomas, Callanan, Mary, Tessoulin, Benoit

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Prognostic value of postinduction medullary myeloid recovery by flow cytometry in acute myeloid leukemia by Row, Céline, Lechevalier, Nicolas, Vial, Jean Philippe, Mimoun, Aguirre, Bastie, Jean Noel, Lafon, Ingrid, Pigneux, Arnaud, Leguay, Thibaut, Callanan, Mary, Maynadie, Marc, Béné, Marie C., Dumas, Pierre Yves, Guy, Julien

“…Risk stratification and treatment response evaluation are key features in acute myeloid leukemia (AML) management. Immunophenotypic and molecular approaches…”
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Radioresistance mechanisms of mammary tumor initiating cells: Unreliable biological conclusions based on limiting dilution assays by Bonnefoix, Thierry, Callanan, Mary

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