Search Results - "Callahan, Michael F."

Microarray analysis reveals age-related differences in gene expression during the development of osteoarthritis in mice by Loeser, Richard F., Olex, Amy L., McNulty, Margaret A., Carlson, Cathy S., Callahan, Michael F., Ferguson, Cristin M., Chou, Jeff, Leng, Xiaoyan, Fetrow, Jacquelyn S.

“…Objective To better understand the contribution of age to the development of osteoarthritis (OA). Methods Surgical destabilization of the medial meniscus (DMM)…”
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Effects of anesthetics on systemic hemodynamics in mice by Janssen, Ben J A, De Celle, Tijl, Debets, Jacques J M, Brouns, Agnieszka E, Callahan, Michael F, Smith, Thomas L

“…The aim of this study was to compare the systemic hemodynamic effects of four commonly used anesthetic regimens in mice that were chronically instrumented for…”
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Metabolism of [13C5]hydroxyproline in vitro and in vivo: implications for primary hyperoxaluria by Jiang, Juquan, Johnson, Lynnette C, Knight, John, Callahan, Michael F, Riedel, Travis J, Holmes, Ross P, Lowther, W Todd

“…Hydroxyproline (Hyp) metabolism is a key source of glyoxylate production in the body and may be a major contributor to excessive oxalate production in the…”
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The Effect of Botulinum Neurotoxin-A on Blood Flow in Rats: A Potential Mechanism for Treatment of Raynaud Phenomenon by Stone, Austin V., MD, Koman, L. Andrew, MD, Callahan, Michael F., PhD, Eckman, Delrae M., PhD, Smith, Beth P., PhD, Plate, Johannes F., MD, Smith, Thomas L., PhD

“…Purpose Botulinum neurotoxin-A (BoNTA) is used to treat several disorders, including Raynaud phenomenon. Recent investigations cite toxin-induced increases in…”
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Pharmacokinetics and safety of TCMCB07, a melanocortin‐4 antagonist peptide in dogs by Axiak‐Bechtel, Sandra M., Leach, Stacey B., Scholten, David G., Newton‐Northup, Jessica R., Johnson, Brendan J., Durham, H. E., Gruber, Kenneth A., Callahan, Michael F.

“…The melanocortin‐4 receptor (MC4R) antagonistic peptide TCMCB07 was developed for the treatment of cachexia. The objectives of this study were to examine…”
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A Comprehensive Histological Assessment of Osteoarthritis Lesions in Mice by McNulty, Margaret A., Loeser, Richard F., Davey, Cynthia, Callahan, Michael F., Ferguson, Cristin M., Carlson, Cathy S.

“…Objective: Accurate histological assessment of osteoarthritis (OA) is critical in studies evaluating the effects of interventions on disease severity. The…”
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Melanocortin-4 receptor antagonist TCMCB07 ameliorates cancer- and chronic kidney disease-associated cachexia by Zhu, Xinxia, Callahan, Michael F, Gruber, Kenneth A, Szumowski, Marek, Marks, Daniel L

“…Cachexia, a devastating wasting syndrome characterized by severe weight loss with specific losses of muscle and adipose tissue, is driven by reduced food…”
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Chemical Denervation with Botulinum Neurotoxin A Improves the Surgical Manipulation of the Muscle–Tendon Unit: An Experimental Study in an Animal Model by Mannava, Sandeep, MD, Callahan, Michael F., PhD, Trach, Simon M., BS, Wiggins, Walter F., BS, Smith, Beth P., PhD, Koman, L. Andrew, MD, Smith, Thomas L., PhD, Tuohy, Christopher J., MD

“…Purpose The chemical denervation that results from botulinum neurotoxin A (BoNT-A) causes a temporary, reversible paresis that can result in easier surgical…”
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Chronic Ca2+/Calmodulin-Dependent Protein Kinase II Inhibition Rescues Advanced Heart Failure by Liu, Yixi, Shao, Qun, Cheng, Heng-Jie, Li, Tiankai, Zhang, Xiaowei, Callahan, Michael F, Herrington, David, Kitzman, Dalane, Zhao, David, Cheng, Che-Ping

“…Ca2+/calmodulin-dependent protein kinase II (CaMKII) is upregulated in congestive heart failure (CHF), contributing to electrical, structural, and functional…”
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Chronic Ca 2+ /Calmodulin-Dependent Protein Kinase II Inhibition Rescues Advanced Heart Failure by Liu, Yixi, Shao, Qun, Cheng, Heng-Jie, Li, Tiankai, Zhang, Xiaowei, Callahan, Michael F, Herrington, David, Kitzman, Dalane, Zhao, David, Cheng, Che-Ping

“…Ca /calmodulin-dependent protein kinase II (CaMKII) is upregulated in congestive heart failure (CHF), contributing to electrical, structural, and functional…”
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Stress increases oxytocin release within the hypothalamic paraventricular nucleus by Nishioka, Tatsuya, Anselmo-Franci, Janete A, Li, Ping, Callahan, Michael F, Morris, Mariana

“…Evidence indicates that the hypothalamic paraventricular nucleus (PVN) and oxytocin (OT) neurons in particular play a role in the physiological response to…”
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Reduction of ectopic bone growth in critically-sized rat mandible defects by delivery of rhBMP-2 from kerateine biomaterials by Kowalczewski, Christine J, Tombyln, Seth, Wasnick, David C, Hughes, Michael R, Ellenburg, Mary D, Callahan, Michael F, Smith, Thomas L, Van Dyke, Mark E, Burnett, Luke R, Saul, Justin M

“…Abstract Absorbable collagen sponges (ACS) are used clinically as carriers of recombinant human bone morphogenetic protein 2 (rhBMP-2) to promote bone…”
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Abnormal water metabolism in mice lacking the type 1A receptor for ANG II by Oliverio, M I, Delnomdedieu, M, Best, C F, Li, P, Morris, M, Callahan, M F, Johnson, G A, Smithies, O, Coffman, T M

“…Mice lacking AT(1A) receptors for ANG II have a defect in urinary concentration manifested by an inability to increase urinary osmolality to levels seen in…”
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Safety of TCMCB07, a melanocortin‐4 antagonist peptide, in dogs with naturally occurring cachexia by Axiak‐Bechtel, Sandra M., Leach, Stacey B., Newton‐Northup, Jessica R., Milner, Rowan J., Fox‐Alvarez, Stacey A., Fagman, Lana I., Young, Kaylee A., Tate, Deborah J., Wright, Zachary M., Chretin, John D., Allen, Justin W., Yoshimoto, Sean K., Selting, Kimberly A., Flesner, Brian K., White, Carrie R., Mills, Tracy, Aherne, Michael, Bergman, Philip J., Qi, LeAnn, Gruber, Kenneth A., Callahan, Michael F.

“…Background The melanocortin 4 antagonist TCMCB07 is safe and effective in reversing cachexia caused by sepsis or cancer in rodents. The safety and…”
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Overexpression myocardial inducible nitric oxide synthase exacerbates cardiac dysfunction and beta-adrenergic desensitization in experimental hypothyroidism by Shao, Qun, Cheng, Heng-Jie, Callahan, Michael F, Kitzman, Dalane W, Li, Wei-Min, Cheng, Che Ping

“…ABSTRACT Background Altered nitric oxide synthase (NOS) has been implicated in the pathophysiology of heart failure (HF). Recent evidence links hypothyroidism…”
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Angiotensin-(1-7) Attenuates Skeletal Muscle Fibrosis and Stiffening in a Mouse Model of Extremity Sarcoma Radiation Therapy by Willey, Jeffrey S., Bracey, Daniel N., Gallagher, Patricia E., Tallant, E. Ann, Wiggins, Walter F., Callahan, Michael F., Smith, Thomas L., Emory, Cynthia L.

“…Radiation-induced fibrosis (RIF) of musculoskeletal tissue is a common complication of radiation therapy for extremity soft-tissue sarcoma, with no…”
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Metabolism of primed, constant infusions of [1,2-13 C2 ] glycine and [1-13 C1 ] phenylalanine to urinary oxalate by Knight, John, Assimos, Dean G, Callahan, Michael F, Holmes, Ross P

“…Abstract Experiments in humans and rodents using oral doses of glycine and phenylalanine have suggested that the metabolism of these amino acids contributes to…”
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Angiotensin-(1-7) inhibits growth of human lung adenocarcinoma xenografts in nude mice through a reduction in cyclooxygenase-2 by MENON, Jyotsana, SOTO-PANTOJA, David R, CALLAHAN, Michael F, CLINE, J. Mark, FERRARIO, Carlos M, TALLANT, E. Ann, GALLAGHERL, Patricia E

“…Angiotensin-(1-7) [Ang-(1-7)] is an endogenous peptide of the renin-angiotensin system with vasodilator and antiproliferative properties. Our previous studies…”
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Role of the Hypoxia-Inducible Factor Pathway in Normal and Osteoarthritic Meniscus and in Mice after Destabilization of the Medial Meniscus by Stone, Austin V., Loeser, Richard F., Callahan, Michael F., McNulty, Margaret A., Long, David L., Yammani, Raghunatha R., Bean, Sara, Vanderman, Kadie, Chubinskaya, Susan, Ferguson, Cristin M.

“…Objective Meniscus injury and the hypoxia-inducible factor (HIF) pathway are independently linked to osteoarthritis pathogenesis, but the role of the meniscus…”
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The Impact of Dietary Calcium and Oxalate Ratios on Stone Risk by Lange, Jessica N, Wood, Kyle D, Mufarrij, Patrick W, Callahan, Michael F, Easter, Linda, Knight, John, Holmes, Ross P, Assimos, Dean G

“…Objective To determine whether the ratio of dietary calcium and oxalate consumption at mealtime affects gastrointestinal oxalate absorption and urinary oxalate…”
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