Search Results - "Callahan, L A"

MitoQ administration prevents endotoxin-induced cardiac dysfunction by Supinski, G S, Murphy, M P, Callahan, L A

“…Sepsis elicits severe alterations in cardiac function, impairing cardiac mitochondrial and pressure-generating capacity. Currently, there are no therapies to…”
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Caspase and calpain activation both contribute to sepsis-induced diaphragmatic weakness by Supinski, G. S, Wang, W, Callahan, L. A

“…Division of Pulmonary, Critical Care and Sleep Medicine, University of Kentucky, Lexington, Kentucky Submitted 1 April 2009 ; accepted in final form 3 August…”
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Effect of proteasome inhibitors on endotoxin-induced diaphragm dysfunction by Supinski, G S, Vanags, J, Callahan, L A

“…Infections produce severe respiratory muscle dysfunction. It is known that the proteasome proteolytic system is activated in skeletal muscle in sepsis, and it…”
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Double-stranded RNA-dependent protein kinase activation modulates endotoxin-induced diaphragm weakness by SUPINSKI, G. S, CALLAHAN, L. A

“…Diaphragm caspase-8 activation plays a key role in modulating sepsis-induced respiratory muscle dysfunction. It is also known that double-stranded…”
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Superoxide, hydroxyl radical, and hydrogen peroxide effects on single-diaphragm fiber contractile apparatus by Callahan, L. A, She, Z. W, Nosek, T. M

“…1  Division of Pulmonary and Critical Care Medicine, Department of Medicine, and 3  Department of Physiology and Biophysics, Case Western Reserve University,…”
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PLA2 dependence of diaphragm mitochondrial formation of reactive oxygen species by Nethery, D, Callahan, L. A, Stofan, D, Mattera, R, DiMarco, A, Supinski, G

“…Pulmonary Division, Department of Medicine, Case Western Reserve University, and MetroHealth Medical Center, Cleveland, Ohio 44109 Contraction-induced…”
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Peroxynitrite induces contractile dysfunction and lipid peroxidation in the diaphragm by Supinski, G, Stofan, D, Callahan, L. A, Nethery, D, Nosek, T. M, DiMarco, A

“…Pulmonary Division, Department of Medicine, Case Western Reserve University, Cleveland 44106; and Metrohealth Medical Center, Cleveland, Ohio 44109…”
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Free Radical-Induced Contractile Protein Dysfunction in Endotoxin-Induced Sepsis by Callahan, Leigh Ann, Nethery, David, Stofan, Daniel, DiMarco, Anthony, Supinski, Gerald

“…Recent studies have indicated that sepsis is associated with enhanced generation of several free-radical species (nitric oxide [NO], superoxide, hydrogen…”
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Endotoxin administration alters the force vs. pCa relationship of skeletal muscle fibers by Supinski, G, Nethery, D, Nosek, T M, Callahan, L A, Stofan, D, DiMarco, A

“…Recent work indicates that endotoxemia elicits severe reductions in skeletal muscle force-generating capacity. The subcellular alterations responsible for…”
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Increased superoxide production during fatigue in the perfused rat diaphragm by KOLBECK, R. C, SHE, Z.-W, CALLAHAN, L. A, NOSEK, T. M

“…This study test the hypothesis that a temporal relationship exists between the production of superoxide anion (O2-) and the contractile activity of perfused…”
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Modulation of release of reactive oxygen species by the contracting diaphragm by STOFAN, D. A, CALLAHAN, L. A, DIMARCO, A. F, NETHERY, D. E, SUPINSKI, G. S

“…Recent reports have demonstrated that superoxide is released by the contracting diaphragm. Moreover, extracellular scavengers of superoxide (i.e., exogenously…”
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Exercise in sickle cell anemia: effect on inflammatory and vasoactive mediators by Barbeau, P, Woods, K F, Ramsey, L T, Litaker, M S, Pollock, D M, Pollock, J S, Callahan, L A, Kutlar, A, Mensah, G A, Gutin, B

“…The aim of this study was to determine the response of inflammatory and vasoactive mediators to 3 consecutive days of exercise in African-American women with…”
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PLA(2) dependence of diaphragm mitochondrial formation of reactive oxygen species by Nethery, D, Callahan, L A, Stofan, D, Mattera, R, DiMarco, A, Supinski, G

“…Contraction-induced respiratory muscle fatigue and sepsis-related reductions in respiratory muscle force-generating capacity are mediated, at least in part, by…”
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Free radicals alter maximal diaphragmatic mitochondrial oxygen consumption in endotoxin-induced sepsis by Callahan, Leigh A, Stofan, Daniel A, Szweda, Luke I, Nethery, David E, Supinski, Gerald S

“…Recent studies indicate that sepsis is associated with enhanced generation of several free radical species (nitric oxide, superoxide, hydrogen peroxide) in…”
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Maintenance of an insanity defense under Montana's "abolition" of the insanity defense by Steadman, H J, Callahan, L A, Robbins, P C, Morrissey, J P

“…In 1979, Montana's insanity defense was replaced with the more restrictive mens rea defense, a change that has been described as an example of "abolition" of…”
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Factors Associated with the Conditional Release of Persons Acquitted by Reason of Insanity: A Decision Tree Approach by Callahan, Lisa A, Silver, Eric

“…Most NGRI (not guilty by reason of insanity) acquittees are hospitalized for some period of time following acquittal, which raises the question of when an…”
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Body composition in women with sickle cell disease by Woods, K F, Ramsey, L T, Callahan, L A, Mensah, G A, Litaker, M S, Kutlar, A, Barbeau, P, Gutin, B

“…Adults with sickle cell disease (SCD) have increased morbidity and low perceived health status, similar to patients with other chronic conditions. These…”
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Revocation of Conditional Release: A Comparison of Individual and Program Characteristics Across Four U.S. States by Callahan, Lisa A., Silver, Eric

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Effects of protein kinase A inhibition on rat diaphragm force generation by Supinski, G, Stofan, D, Callahan, L.A, Nethery, D, DiMarco, A

“…Although protein kinases are known to play a role in modulating a variety of intracellular functions, the direct effect of inhibition of these enzymes on…”
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Impact of endovascular-assisted in situ saphenous vein bypass technique on hospital costs by Nelson, P R, McEnaney, P M, Callahan, L A, Arous, E J

“…Our initial experience with endovascular-assisted in situ saphenous vein bypass (EISVB) showed patency rates to be comparable to those with conventional in…”
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