Search Results - "Callaghan, Paul D"

Metal Transfer among Organs Following Short- and Long-Term Exposures Using Autoradiography: Cadmium Bioaccumulation by the Freshwater Prawn Macrobrachium australiense by Cresswell, Tom, Mazumder, Debashish, Callaghan, Paul D, Nguyen, An, Corry, Michael, Simpson, Stuart L

“…The uptake, depuration, and organ distribution of the radioisotope 109Cd were used to explore the internal kinetics of this nonessential metal following…”
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Mephedrone in adolescent rats: residual memory impairment and acute but not lasting 5-HT depletion by Motbey, Craig P, Karanges, Emily, Li, Kong M, Wilkinson, Shane, Winstock, Adam R, Ramsay, John, Hicks, Callum, Kendig, Michael D, Wyatt, Naomi, Callaghan, Paul D, McGregor, Iain S

“…Mephedrone (4-methylmethcathinone, MMC) is a popular recreational drug, yet its potential harms are yet to be fully established. The current study examined the…”
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Plasma Drug Concentrations and Physiological Measures in 'Dance Party' Participants by IRVINE, Rodney J, KEANE, Michael, FELGATE, Peter, MCCANN, Una D, CALLAGHAN, Paul D, WHITE, Jason M

“…The increasing use of (+/-) 3,4-methylenedioxymethamphetamine (MDMA) in the setting of large dance parties ('raves') and clubs has been the source of some…”
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ABC Efflux Transporters and Solute Carriers in the Early Developing Brain of a Marsupial Monodelphis domestica (South American Gray Short‐Tailed Opossum) by Huang, Yifan, Dziegielewska, Katarzyna M., Habgood, Mark D., Qiu, Fiona, Leandro, Ana C. C., Callaghan, Paul D., Curran, Joanne E., VandeBerg, John L., Saunders, Norman R.

“…ABSTRACT This study used a marsupial Monodelphis domestica, which is born very immature and most of its development is postnatal without placental protection…”
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Bioaccumulation and Biodistribution of Selenium in Metamorphosing Tadpoles by Lanctôt, Chantal M, Cresswell, Tom, Callaghan, Paul D, Melvin, Steven D

“…Selenium is an important macronutrient with a very narrow margin between essentiality and toxicity. Amphibians are hypothesized to be particularly sensitive…”
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Comparative analysis of novel decynium-22 analogs to inhibit transport by the low-affinity, high-capacity monoamine transporters, organic cation transporters 2 and 3, and plasma membrane monoamine transporter by Fraser-Spears, Rheaclare, Krause-Heuer, Anwen M., Basiouny, Mohamed, Mayer, Felix P., Manishimwe, Retrouvailles, Wyatt, Naomi A., Dobrowolski, Jeremy C., Roberts, Maxine P., Greguric, Ivan, Kumar, Naresh, Koek, Wouter, Sitte, Harald H., Callaghan, Paul D., Fraser, Benjamin H., Daws, Lynette C.

“…Growing evidence supports involvement of low-affinity/high-capacity organic cation transporters (OCTs) and plasma membrane monoamine transporter (PMAT) in…”
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Bioaccumulation Kinetics and Organ Distribution of Cadmium and Zinc in the Freshwater Decapod Crustacean Macrobrachium australiense by Cresswell, Tom, Simpson, Stuart L, Mazumder, Debashish, Callaghan, Paul D, Nguyen, An P

“…This study used the radioisotopes 109Cd and 65Zn to explore the uptake, retention and organ distribution of these nonessential and essential metals from…”
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Adolescent Rats Find Repeated Δ -THC Less Aversive Than Adult Rats but Display Greater Residual Cognitive Deficits and Changes in Hippocampal Protein Expression Following Exposure by Quinn, Heidi R, Matsumoto, Izuru, Callaghan, Paul D, Long, Leonora E, Arnold, Jonathon C, Gunasekaran, Nathan, Thompson, Murray R, Dawson, Bronwyn, Mallet, Paul E, Kashem, Mohammed A, Matsuda-Matsumoto, Haruka, Iwazaki, Takeshi, McGregor, Iain S

“…The current study examined whether adolescent rats are more vulnerable than adult rats to the lasting adverse effects of cannabinoid exposure on brain and…”
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The Differential Binding of Antipsychotic Drugs to the ABC Transporter P-Glycoprotein Predicts Cannabinoid-Antipsychotic Drug Interactions by Brzozowska, Natalia I, de Tonnerre, Erik J, Li, Kong M, Wang, Xiao Suo, Boucher, Aurelie A, Callaghan, Paul D, Kuligowski, Michael, Wong, Alex, Arnold, Jonathon C

“…Cannabis use increases rates of psychotic relapse and treatment failure in schizophrenia patients. Clinical studies suggest that cannabis use reduces the…”
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High levels of intravenous mephedrone (4-methylmethcathinone) self-administration in rats: Neural consequences and comparison with methamphetamine by Motbey, Craig P, Clemens, Kelly J, Apetz, Nadine, Winstock, Adam R, Ramsey, John, Li, Kong M, Wyatt, Naomi, Callaghan, Paul D, Bowen, Michael T, Cornish, Jennifer L, McGregor, Iain S

“…Mephedrone (MMC) is a relatively new recreational drug that has rapidly increased in popularity in recent years. This study explored the characteristics of…”
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MDMA-induced c-Fos expression in oxytocin-containing neurons is blocked by pretreatment with the 5-HT-1A receptor antagonist WAY 100635 by Hunt, Glenn E, McGregor, Iain S, Cornish, Jennifer L, Callaghan, Paul D

“…Highlights ► WAY 100635, a 5HT1A antagonist reduced the MDMA-induced c-Fos expression in two key oxytocin areas – the SON and PVN. ► WAY 100635 also attenuated…”
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PET imaging of brain inflammation during early epileptogenesis in a rat model of temporal lobe epilepsy by Dedeurwaerdere, Stefanie, Callaghan, Paul D, Pham, Tien, Rahardjo, Gita L, Amhaoul, Halima, Berghofer, Paula, Quinlivan, Mitchell, Mattner, Filomena, Loc'h, Christian, Katsifis, Andrew, Grégoire, Marie-Claude

“…Background Recently, inflammatory cascades have been suggested as a target for epilepsy therapy. Positron emission tomography (PET) imaging offers the unique…”
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Investigation of elemental changes in brain tissues following excitotoxic injury by Siegele, Rainer, Howell, Nicholas R., Callaghan, Paul D., Pastuovic, Zeljko

“…Recently the ANSTO heavy ion microprobe has been used for elemental mapping of thin brain tissue sections. The fact that a very small portion of the proton…”
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Evaluation of the antidepressant therapeutic potential of isocyanine and pseudoisocyanine analogues of the organic cation decynium-22 by Krause-Heuer, Anwen M., Fraser-Spears, Rheaclare, Dobrowolski, Jeremy C., Ashford, Mark E., Wyatt, Naomi A., Roberts, Maxine P., Gould, Georgianna G., Cheah, Wai-Ching, Ng, Clarissa K.L., Bhadbhade, Mohan, Zhang, Bo, Greguric, Ivan, Wheate, Nial J., Kumar, Naresh, Koek, Wouter, Callaghan, Paul D., Daws, Lynette C., Fraser, Benjamin H.

“…Herein we describe the synthesis and evaluation of antidepressant properties of seven analogues (1–7) of the low affinity/high capacity transporter blocker…”
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Differential behavioural and neurochemical outcomes from chronic paroxetine treatment in adolescent and adult rats: a model of adverse antidepressant effects in human adolescents? by Karanges, Emily, Li, Kong M., Motbey, Craig, Callaghan, Paul D., Katsifis, Andrew, McGregor, Iain S.

“…Selective serotonin reuptake inhibitor use is associated with increased risk of suicidal ideation in adolescent humans, yet the neuropharmacological basis of…”
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Aggregation in quads but not pairs of rats exposed to cat odor or bright light by Bowen, Michael T., Keats, Kirily, Kendig, Michael D., Cakic, Vince, Callaghan, Paul D., McGregor, Iain S.

“…► The response of groups of two and four rats to cat odor and bright light is tested. ► Groups of four but not two rats huddle together in response to both…”
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Cocaine Increases Dopamine Uptake and Cell Surface Expression of Dopamine Transporters by Daws, Lynette C., Callaghan, Paul D., Morón, José A., Kahlig, Kris M., Shippenberg, Toni S., Javitch, Jonathan A., Galli, Aurelio

“…In HEK 293 cells expressing the human dopamine transporter (DAT), a 10-min incubation with 10 μM cocaine followed by extensive washing resulted in a 30%…”
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Reduced sensitivity to MDMA-induced facilitation of social behaviour in MDMA pre-exposed rats by Thompson, Murray R., Callaghan, Paul D., Hunt, Glenn E., McGregor, Iain S.

“…The acute effects of the party drug 3,4-methylenedioxymethamphetamine (MDMA, “Ecstasy”) in humans include feelings of love, closeness towards other people and…”
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Differences in the in vivo dynamics of neurotransmitter release and serotonin uptake after acute para-methoxyamphetamine and 3,4-methylenedioxymethamphetamine revealed by chronoamperometry by Callaghan, Paul D., Irvine, Rodney J., Daws, Lynette C.

“…Illicit use of p-methoxyamphetamine (PMA) is rapidly increasing. However, little is known about the acute effects of PMA on neurotransmission in vivo…”
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High ambient temperature increases intravenous methamphetamine self-administration on fixed and progressive ratio schedules in rats by Cornish, Jennifer L., Clemens, Kelly J., Thompson, Murray R., Callaghan, Paul D., Dawson, Bronwyn, McGregor, Iain S.

“…Methamphetamine is a drug that is often consumed at dance parties or nightclubs where the ambient temperature is high. The present study determined whether…”
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