Search Results - "Callaghan, Juliana"

A framework for the development of effective anti-metastatic agents by Anderson, Robin L., Balasas, Theo, Callaghan, Juliana, Coombes, R. Charles, Evans, Jeff, Hall, Jacqueline A., Kinrade, Sally, Jones, David, Jones, Paul S., Jones, Rob, Marshall, John F., Panico, Maria Beatrice, Shaw, Jacqui A., Steeg, Patricia S., Sullivan, Mark, Tong, Warwick, Westwell, Andrew D., Ritchie, James W. A.

“…Most cancer-related deaths are a result of metastasis, and thus the importance of this process as a target of therapy cannot be understated. By asking ‘how can…”
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Structure of the HP1 chromodomain bound to histone H3 methylated at lysine 9 by Murzina, Natalia V, Laue, Ernest D, Nielsen, Peter R, Nietlispach, Daniel, Mott, Helen R, Callaghan, Juliana, Bannister, Andrew, Kouzarides, Tony, Murzin, Alexey G

“…Specific modifications to histones are essential epigenetic markers-heritable changes in gene expression that do not affect the DNA sequence. Methylation of…”
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Molecular Basis for Jagged-1/Serrate Ligand Recognition by the Notch Receptor by Whiteman, Pat, de Madrid, Beatriz Hernandez, Taylor, Paul, Li, Demin, Heslop, Rebecca, Viticheep, Nattnee, Tan, Joyce Zi, Shimizu, Hideyuki, Callaghan, Juliana, Masiero, Massimo, Li, Ji Liang, Banham, Alison H., Harris, Adrian L., Lea, Susan M., Redfield, Christina, Baron, Martin, Handford, Penny A.

“…We have mapped a Jagged/Serrate-binding site to specific residues within the 12th EGF domain of human and Drosophila Notch. Two critical residues, involved in…”
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CHR-2797: an antiproliferative aminopeptidase inhibitor that leads to amino acid deprivation in human leukemic cells by Krige, David, Needham, Lindsey A, Bawden, Lindsay J, Flores, Nicolas, Farmer, Hannah, Miles, Lauren E C, Stone, Erica, Callaghan, Juliana, Chandler, Stephen, Clark, Vanessa L, Kirwin-Jones, Patricia, Legris, Valérie, Owen, Jo, Patel, Thakor, Wood, Steve, Box, Gary, Laber, David, Odedra, Rajesh, Wright, Annette, Wood, L Michael, Eccles, Suzanne A, Bone, Elisabeth A, Ayscough, Andrew, Drummond, Alan H

“…CHR-2797 is a novel metalloenzyme inhibitor that is converted into a pharmacologically active acid product (CHR-79888) inside cells. CHR-79888 is a potent…”
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Expression, purification, and biophysical studies of chromodomain proteins by Nielsen, Peter R, Callaghan, Juliana, Murzin, Alexey G, Murzina, Natalia V, Laue, Ernest D

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