Search Results - "Callado, L F"

Phosphorylation of FADD (Fas-associated death domain protein) at serine 194 is increased in the prefrontal cortex of opiate abusers: Relation to mitogen activated protein kinase, phosphoprotein enriched in astrocytes of 15 kDa, and Akt signaling pathways involved in neuroplasticity by Ramos-Miguel, A, García-Fuster, M.J, Callado, L.F, La Harpe, R, Meana, J.J, García-Sevilla, J.A

“…Abstract Fas-associated protein with death domain (FADD) is a multifunctional protein that can induce both apoptotic and non-apoptotic actions. Recently, FADD…”
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Characterization of CB1 cannabinoid receptor immunoreactivity in postmortem human brain homogenates by De Jesús, M. López, Sallés, J., Meana, J.J., Callado, L.F.

“…The CB1 cannabinoid receptor (CB1) is the predominant type of cannabinoid receptor in the CNS, in which it displays a unique anatomical distribution and is…”
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Oral and Palmitate Paliperidone Long-Acting Injectable Formulations’ Use in Schizophrenia Spectrum Disorders: A Retrospective Cohort Study from the First Episode Psychosis Intervention Program (CRUPEP) by Segarra, R, Recio-Barbero, M, Sáenz-Herrero, M, Mentxaka, O, Cabezas-Garduño, J, Eguíluz, J I, Callado, L F

“…Abstract Background Long-acting injectable antipsychotics (LAIs) may be a suitable therapeutic option for those patients in earlier stages of psychosis to…”
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Aminopeptidase activity in the postmortem brain of human heroin addicts by Larrinaga, G., Gil, J., Meana, J.J., Ruiz, F., Callado, L.F., Irazusta, J.

“…Several studies have reported that the chronic administration of opioids induces changes in the biosynthesis of endogenous opioid peptides or their precursors…”
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Effects of tramadol stereoisomers on norepinephrine efflux and uptake in the rat locus coeruleus measured by real time voltammetry by Halfenny, D. M., Callado, L. F., Hopwood, S. E., Bamigbade, T. A., Langford, R. M., Stamford, J. A.

“…Despite its structural similarity to codeine, tramadol is an unusual analgesic whose antinociceptive efficacy is not solely a result of opioid actions but also…”
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Imidazoline I2 receptor density increases with the malignancy of human gliomas by Callado, L F, Martín-Gómez, J I, Ruiz, J, Garibi, J M, Meana, J J

“…Background: Current glioma grading schemes are limited by subjective histological criteria. Imidazoline I2 receptors are principally expressed on glial cells…”
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The inverse agonist effect of rimonabant on G protein activation is not mediated by the cannabinoid CB1 receptor: Evidence from postmortem human brain by Erdozain, A.M., Diez-Alarcia, R., Meana, J.J., Callado, L.F.

“…Rimonabant (SR141716) was the first potent and selective cannabinoid CB1 receptor antagonist synthesized. Several data support that rimonabant behaves as an…”
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Brain RGS4 and RGS10 protein expression in schizophrenia and depression. Effect of drug treatment by Rivero, G., Gabilondo, A. M., García-Sevilla, J. A., Callado, L. F., La Harpe, R., Morentin, B., Meana, J. J.

“…Rationale Regulator of G-protein signaling (RGS) proteins, RGS4 and RGS10, may be involved in the pathophysiology of schizophrenia. RGS4 has attracted special…”
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Molecular adaptations of apoptotic pathways and signaling partners in the cerebral cortex of human cocaine addicts and cocaine-treated rats by Álvaro-Bartolomé, M, La Harpe, R, Callado, L.F, Meana, J.J, García-Sevilla, J.A

“…Abstract Cocaine induces apoptotic effects in cultured cells and in the developing brain, but the aberrant activation of cell death in the adult brain remains…”
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Effects of chronic tramadol on pre- and post-synaptic measures of monoamine function by Hopwood, Sarah E., Owesson, Catarina A., Callado, Luis F., McLaughlin, Daniel P., Stamford, Jonathan A.

“…The atypical analgesic tramadol has strong structural similarities to the antidepressant venlafaxine and is a mixed noradrenaline (NA) and serotonin (5-HT)…”
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Non-adrenoceptor [3H]idazoxan binding sites (I2-imidazoline sites) are increased in postmortem brain from patients with Alzheimer's disease by Ruiz, J, Martín, I, Callado, L F, Meana, J J, Barturen, F, García-Sevilla, J A

“…The I2-imidazoline site (a non-adrenergic mitochondrial site for which a glial location has been proposed and that is associated with the B-form of the enzyme…”
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Effects of dizocilpine (MK 801) on noradrenaline, serotonin and dopamine release and uptake by Callado, Luis F, Hopwood, Sarah E, Hancock, Pamela J, Stamford, Jonathan A

“…In the present study, we examined the actions of the NMDA antagonist dizocilpine (MK801) on electrically evoked release and uptake of noradrenaline (NA) in the…”
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Is tramadol an antidepressant? by Halfpenny, D M, Callado, L F, Stamford, J A

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Stereoselective effects of ketamine on dopamine, serotonin and noradrenaline release and uptake in rat brain slices by Tso, Michelle M., Blatchford, Karen L., Callado, Luis F., McLaughlin, Daniel P., Stamford, Jonathan A.

“…Ketamine (2-(2-chlorophenyl)-(1-methylamino)-cyclohexanone) is a rapid-acting dissociative general anaesthetic whose hallucinogenic properties have made it a…”
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The Density of Monoamine Oxidase B Sites Is Not Altered in the Postmortem Brain of Alcoholics by Maeztu, Ana I., Ballesteros, Javier, Callado, Luis F., Gutiérrez, Miguel, Meana, J. Javier

“…The status of the enzyme monoamine oxidase B (MAO‐B) was directly evaluated in the postmortem brain from 20 alcoholics and 23 matched controls. The density of…”
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Spatiotemporal interaction of alpha(2) autoreceptors and noradrenaline transporters in the rat locus coeruleus: implications for volume transmission by Callado, L F, Stamford, J A

“…We investigated the roles of alpha(2) autoreceptors and noradrenaline (NA) transporters on NA efflux and uptake in the rat locus coeruleus after electrical…”
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Comparative assessment of current antidepressants efficacy and search for new targets and strategies for the treatment of depression by Callado, L F, Ballesteros, J, Uriguen, L, Ortega, J E, Diez-Alarcia, R, Zabala, A, Eguiluz, J I, Querejeta, I, Gutierrez, M, Meana, J J

“…Depression is a multifactorial disease with a high prevalence worldwide. Despite the advances in drug discovery and therapeutic options there are still…”
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I2-imidazoline receptors and monoamine oxidase B enzyme sites in human brain : covariation with age by BALLESTEROS, J, MAEZTU, A. I, CALLADO, L. F, GUTIERREZ, M, GARCIA-SEVILLA, J. A, MEANA, J. J

“…An association between monoamino oxidase B enzyme (MAO-B) sites and I(2)-imidazoline receptors (I(2)-IR) has been established in human brain on the basis of…”
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Differential Postmortem Delay Effect on Agonist-Mediated Phospholipase Cβ Activity in Human Cortical Crude and Synaptosomal Brain Membranes by Garro, M. Asier, López de Jesús, Maider, Ruíz de Azúa, Iñigo, Callado, Luis F., Meana, J. Javier, Sallés, Joan

“…The phosphoinositide signal transduction system, and particularly, phospholipase C beta isozymes, are relevant in the etiopathogeny of human neuropsychiatric…”
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Propofol decreases stimulated dopamine release in the rat nucleus accumbens by a mechanism independent of dopamine D2, GABAA and NMDA receptors by Schulte, D, Callado, L F, Davidson, C, Phillips, P E, Roewer, N, Schulte am Esch, J, Stamford, J A

“…Although propofol (2,6-di-isopropylphenol) is a popular i.v. general anaesthetic, it has been suggested to have abuse potential. As many drugs of abuse act…”
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