Search Results - "Calkoen, Friso"

Immunotherapy: genetically agnostic in BCP-ALL? by Zwaan, Christian Michel, Calkoen, Friso G.J.

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BEHAV3D: a 3D live imaging platform for comprehensive analysis of engineered T cell behavior and tumor response by Alieva, Maria, Barrera Román, Mario, de Blank, Sam, Petcu, Diana, Zeeman, Amber L., Dautzenberg, Noël M. M., Cornel, Annelisa M., van de Ven, Cesca, Pieters, Rob, den Boer, Monique L., Nierkens, Stefan, Calkoen, Friso G. J., Clevers, Hans, Kuball, Jürgen, Sebestyén, Zsolt, Wehrens, Ellen J., Dekkers, Johanna F., Rios, Anne C.

“…Modeling immuno-oncology by using patient-derived material and immune cell co-cultures can advance our understanding of immune cell tumor targeting in a…”
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Automated production of specific T cells for treatment of refractory viral infections after allogeneic stem cell transplantation by Heinz, Amadeus T, Calkoen, Friso G J, Derbich, Alexander, Miltner, Lea, Seitz, Christian, Doering, Michaela, Braun, Christiane, Atar, Daniel, Schumm, Michael, Heubach, Florian, Arendt, Anne-Marie, Schulz, Ansgar, Schuster, Friedhelm R, Meisel, Roland, Strahm, Brigitte, Finke, Juergen, Heineking, Beatrice, Stetter, Susanne, Silling, Gerda, Stachel, Daniel, Gruhn, Bernd, Debatin, Klaus-Michael, Foell, Juergen, Schulte, Johannes H, Woessmann, Wilhelm, Mauz-Körholz, Christine, Tischer, Johanna, Feuchtinger, Tobias, Handgretinger, Rupert, Lang, Peter

“…Therapy-resistant viral reactivations contribute significantly to mortality after hematopoietic stem cell transplantation. Adoptive cellular therapy with…”
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OV Modulators of the Paediatric Brain TIME: Current Status, Combination Strategies, Limitations and Future Directions by Vazaios, Konstantinos, van Berkum, Ronja E, Calkoen, Friso G, van der Lugt, Jasper, Hulleman, Esther

“…Oncolytic viruses (OVs) are characterised by their preference for infecting and replicating in tumour cells either naturally or after genetic modification,…”
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Poor outcome of patients with COVID-19 after CAR T-cell therapy for B-cell malignancies: results of a multicenter study on behalf of the European Society for Blood and Marrow Transplantation (EBMT) Infectious Diseases Working Party and the European Hematology Association (EHA) Lymphoma Group by Spanjaart, Anne Mea, Ljungman, Per, de La Camara, Rafael, Tridello, Gloria, Ortiz-Maldonado, Valentín, Urbano-Ispizua, Alvaro, Barba, Pere, Kwon, Mi, Caballero, Dolores, Sesques, Pierre, Bachy, Emmanuel, Di Blasi, Roberta, Thieblemont, Catherine, Calkoen, Friso, Mutsaers, Pim, Maertens, Johan, Giannoni, Livia, Nicholson, Emma, Collin, Matthew, Vaz, Carlos Pinho, Metafuni, Elisabetta, Martinez-Lopez, Joaquin, Dignan, Fiona L., Ribera, Josep-Maria, Nagler, Arnon, Folber, Frantisek, Sanderson, Robin, Bloor, Adrian, Ciceri, Fabio, Knelange, Nina, Ayuk, Francis, Kroger, Nicolaus, Kersten, Marie José, Mielke, Stephan

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Chimeric Antigen Receptor (CAR) T-Cell Products for Pediatric Cancers: Why Alternative Development Paths Are Needed by Rossig, Claudia, Pearson, Andrew D, Vassal, Gilles, Scobie, Nicole, Bird, Nick, Blanc, Patricia, Vormoor, H Josef, Calkoen, Friso G, Locatelli, Franco, Bufalo, Francesca Del, Rives, Susana, Jacoby, Elad, Balduzzi, Adriana, Bourquin, Jean-Pierre, Baruchel, André

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Outcome of chimeric antigen receptor T-cell therapy following treatment with inotuzumab ozogamicin in children with relapsed or refractory acute lymphoblastic leukemia by Ceolin, Valeria, Brivio, Erica, van Tinteren, Harm, Rheingold, Susan R., Leahy, Allison, Vormoor, Britta, O’Brien, Maureen M., Rubinstein, Jeremy D., Kalwak, Krzysztof, De Moerloose, Barbara, Jacoby, Elad, Bader, Peter, López-Duarte, Mónica, Goemans, Bianca F., Locatelli, Franco, Hoogerbrugge, Peter, Calkoen, Friso G., Zwaan, Christian Michel

“…Chimeric antigen receptor T cells targeting CD19 (CART-19) have shown remarkable efficacy for relapsed/refractory (R/R) B-cell precursor acute lymphoblastic…”
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INSPIRED Symposium Part 4B: Chimeric Antigen Receptor T Cell Correlative Studies—Established Findings and Future Priorities by Ligon, John A., Ramakrishna, Sneha, Ceppi, Francesco, Calkoen, Friso G.J., Diorio, Caroline, Davis, Kara L., Jacoby, Elad, Gottschalk, Stephen, Schultz, Liora M., Capitini, Christian M.

“…•Correlative studies are important to improve pediatric CAR T cell treatments.•Active areas of research are reviewed from clinical trials and real-world…”
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A Toolkit for Profiling the Immune Landscape of Pediatric Central Nervous System Malignancies by Rozowsky, Jacob S, Meesters-Ensing, Joyce I, Lammers, Julie A S, Belle, Muriël L, Nierkens, Stefan, Kranendonk, Mariëtte E G, Kester, Lennart A, Calkoen, Friso G, van der Lugt, Jasper

“…The prognosis of pediatric central nervous system (CNS) malignancies remains dismal due to limited treatment options, resulting in high mortality rates and…”
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Fludarabine exposure predicts outcome after CD19 CAR T-cell therapy in children and young adults with acute leukemia by Dekker, Linde, Calkoen, Friso G., Jiang, Yilin, Blok, Hilly, Veldkamp, Saskia R., De Koning, Coco, Spoon, Maike, Admiraal, Rick, Hoogerbrugge, Peter, Vormoor, Britta, Vormoor, H. Josef, Visscher, Henk, Bierings, Marc, Van Der Vlugt, Marieke, Van Tinteren, Harm, Nijstad, A. Laura, Huitema, Alwin D.R., Van Der Elst, Kim C.M., Pieters, Rob, Lindemans, Caroline A., Nierkens, Stefan

“…The addition of fludarabine to cyclophosphamide as a lymphodepleting regimen prior to CD19 chimeric antigen receptor (CAR) T-cell therapy significantly…”
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Chimeric Antigen Receptor T-Cell Therapy in Paediatric B-Cell Precursor Acute Lymphoblastic Leukaemia: Curative Treatment Option or Bridge to Transplant? by Buechner, Jochen, Caruana, Ignazio, Künkele, Annette, Rives, Susana, Vettenranta, Kim, Bader, Peter, Peters, Christina, Baruchel, André, Calkoen, Friso G

“…Chimeric antigen receptor T-cell therapy (CAR-T) targeting CD19 has been associated with remarkable responses in paediatric patients and adolescents and young…”
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SARS-CoV-2 infections in pediatric and young adult recipients of chimeric antigen receptor T-cell therapy: an international registry report by McNerney, Kevin Owen, Richards, Rebecca M, Aguayo-Hiraldo, Paibel, Calkoen, Friso G, Talano, Julie-An, Moskop, Amy, Balduzzi, Adriana, Krajewski, Jennifer, Dave, Hema, Vatsayan, Anant, Callahan, Colleen, Liu, Hongyan, Li, Yimei, Davis, Kara Lynn, Maude, Shannon L

“…BackgroundImmunocompromised patients are at increased risk of SARS-CoV-2 infections. Patients undergoing chimeric antigen receptor (CAR) T-cell therapy for…”
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Paving the Way for Immunotherapy in Pediatric Acute Myeloid Leukemia: Current Knowledge and the Way Forward by Koedijk, Joost B., van der Werf, Inge, Calkoen, Friso G., Nierkens, Stefan, Kaspers, Gertjan J. L., Zwaan, Christian Michel, Heidenreich, Olaf

“…Immunotherapeutic agents may be an attractive option to further improve outcomes and to reduce treatment-related toxicity for pediatric AML. While improvements…”
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Mesenchymal stromal cells isolated from children with systemic juvenile idiopathic arthritis suppress innate and adaptive immune responses by Calkoen, Friso G.J, Brinkman, Danielle M.C, Vervat, Carly, van Ostaijen-ten Dam, Monique M, ten Cate, Rebecca, van Tol, Maarten J.D, Ball, Lynne M

“…Abstract Background aims Infusion of mesenchymal stromal cells (MSCs) has been reported to be an effective treatment modality for acute graft-versus-host…”
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Gene-expression and in vitro function of mesenchymal stromal cells are affected in juvenile myelomonocytic leukemia by Calkoen, Friso G J, Vervat, Carly, Eising, Else, Vijfhuizen, Lisanne S, 't Hoen, Peter-Bram A C, van den Heuvel-Eibrink, Marry M, Egeler, R Maarten, van Tol, Maarten J D, Ball, Lynne M

“…An aberrant interaction between hematopoietic stem cells and mesenchymal stromal cells has been linked to disease and shown to contribute to the…”
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The heterogeneous sensitivity of pediatric brain tumors to different oncolytic viruses is predicted by unique gene expression profiles by Vazaios, Konstantinos, Stavrakaki, Εftychia, Vogelezang, Lisette B, Ju, Jie, Waranecki, Piotr, Metselaar, Dennis S, Meel, Michaël H, Kemp, Vera, van den Hoogen, Bernadette G, Hoeben, Rob C, Chiocca, E Antonio, Goins, William F, Stubbs, Andrew, Li, Yunlei, Alonso, Marta M, Calkoen, Friso G, Hulleman, Esther, van der Lugt, Jasper, Lamfers, Martine L M

“…Despite decades of research, the prognosis of high-grade pediatric brain tumors (PBTs) remains dismal; however, recent cases of favorable clinical responses…”
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Mesenchymal Stromal Cell Therapy Is Associated With Increased Adenovirus‐Associated but Not Cytomegalovirus‐Associated Mortality in Children With Severe Acute Graft‐Versus‐Host Disease by Calkoen, Friso G.J., Vervat, Carly, van Halteren, Astrid G.S., Welters, Marij J.P., Veltrop-Duits, Louise A., Lankester, Arjan C., Egeler, R. Maarten, Ball, Lynne M., van Tol, Maarten J.D.

“…This study shows an association between human adenovirus (HAdV) infections occurring after mesenchymal stromal cell (MSC) infusion and decreased survival in…”
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Second‐line treatment for acute graft‐versus‐host disease with mesenchymal stromal cells: A decision model by Thielen, Frederick W., Blommestein, Hedwig M., Oosten, Liesbeth E.M., Calkoen, Friso G., Lankester, Arjan C., Zwaginga, Jaap J., Le Blanc, Katarina, Redondo, Alba, Sánchez‐Guijo, Fermin, Algeri, Mattia, Locatelli, Franco, Fibbe, Wim E., Uyl‐de Groot, Carin A.

“…Objective No standard second‐line treatment exists for acute graft‐versus‐host disease steroid‐refractory (SR‐aGvHD), and long‐term outcomes remain poor…”
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Gastrointestinal Acute Graft-versus-Host Disease in Children: Histology for Diagnosis, Mesenchymal Stromal Cells for Treatment, and Biomarkers for Prediction of Response by Calkoen, Friso G.J, Jol-van der Zijde, Cornelia M, Mearin, M. Luisa, Schweizer, Joachim J, Jansen-Hoogendijk, Anja M, Roelofs, Helene, van Halteren, Astrid G.S, Egeler, R. Maarten, van Tol, Maarten J.D, Ball, Lynne M

“…Abstract Steroid-nonresponsive acute graft-versus-host disease (aGVHD) after hematopoietic stem cell transplantation carries a poor prognosis. Various groups…”
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IMMU-46. MONITORING T-CELL DYNAMICS AND CHECKPOINT EXPRESSION IN THE IMMUNE MICROENVIRONMENT OF PEDIATRIC HIGH GRADE BRAIN TUMORS: THE MIMIC PROGRAM by Meesters-Ensing, Joyce, Carvalheiro, Tiago, Kranendonk, Mariëtte, Van Baarsen, Kirsten, Hoving, Eelco, Calkoen, Friso, van der Lugt, Jasper, Nierkens, Stefan

“…Abstract BACKGROUND Pediatric high grade brain tumors (pHGBT) pose a significant challenge due to limited treatment options and poor prognosis. Understanding…”
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