Search Results - "Calkin, Cynthia V"

Insulin resistance and outcome in bipolar disorder by Calkin, Cynthia V., Ruzickova, Martina, Uher, Rudolf, Hajek, Tomas, Slaney, Claire M., Garnham, Julie S., O'Donovan, M. Claire, Alda, Martin

“…Little is known about the impact of insulin resistance on bipolar disorder. To examine the relationships between insulin resistance, type 2 diabetes and…”
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The relationship between bipolar disorder and type 2 diabetes: more than just co-morbid disorders by Calkin, Cynthia V, Gardner, David M, Ransom, Thomas, Alda, Martin

“…Type 2 diabetes mellitus (T2DM) rates are three times higher in patients with bipolar disorder (BD), compared to the general population. This is a major…”
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Long-term lithium treatment in bipolar disorder: effects on glomerular filtration rate and other metabolic parameters by Tondo, Leonardo, Abramowicz, Maria, Alda, Martin, Bauer, Michael, Bocchetta, Alberto, Bolzani, Lorenza, Calkin, Cynthia V., Chillotti, Caterina, Hidalgo-Mazzei, Diego, Manchia, Mirko, Müller-Oerlinghausen, Bruno, Murru, Andrea, Perugi, Giulio, Pinna, Marco, Quaranta, Giuseppe, Reginaldi, Daniela, Reif, Andreas, Ritter, Philipp, Rybakowski, Janusz K., Saiger, David, Sani, Gabriele, Selle, Valerio, Stamm, Thomas, Vázquez, Gustavo H., Veeh, Julia, Vieta, Eduard, Baldessarini, Ross J.

“…Background Concerns about potential adverse effects of long-term exposure to lithium as a mood-stabilizing treatment notably include altered renal function…”
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Insulin resistance takes center stage: a new paradigm in the progression of bipolar disorder by Calkin, Cynthia V.

“…Bipolar Disorder (BD) is a major psychiatric illness affecting up to 5% of the population. BD can progress over time to a chronic "neuroprogressive" course…”
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Course of bipolar illness worsens after onset of insulin resistance by Cairns, Kathleen, McCarvill, Terrence, Ruzickova, Martina, Calkin, Cynthia V.

“…Cross-sectional studies indicate that comorbid insulin resistance (IR) and type 2 diabetes are associated with a more severe course of bipolar disorder (BD);…”
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Treating Insulin Resistance With Metformin as a Strategy to Improve Clinical Outcomes in Treatment-Resistant Bipolar Depression (the TRIO-BD Study): A Randomized, Quadruple-Masked, Placebo-Controlled Clinical Trial by Calkin, Cynthia V, Chengappa, K N Roy, Cairns, Kathleen, Cookey, Jacob, Gannon, Jessica, Alda, Martin, O'Donovan, Claire, Reardon, Claire, Sanches, Marcos, Růzicková, Martina

“…Therapeutic options are limited for treatment-resistant bipolar depression (TRBD). Insulin resistance (IR) confers increased risk for TRBD. We investigated…”
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Insulin resistance in bipolar disorder: relevance to routine clinical care by Calkin, Cynthia V, Alda, Martin

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Predicting Conversion to Insulin Sensitivity With Metformin: A Promising Tool for Clinicians in Addressing Insulin Resistance and Improving Outcomes in Patients With Treatment Resistant Bipolar Depression by Gannon, Jessica M, Sanchez, Marcos, Lines, Katherine, Cairns, Kathleen, Reardon, Claire, Chengappa, K N Roy, Calkin, Cynthia V

“…Insulin resistance (IR) changes the trajectory of responsive bipolar disorder to a treatment-resistant course. A clinical trial conducted by our group…”
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Early-onset and very-early-onset bipolar disorder: distinct or similar clinical conditions? by Propper, Lukas, Ortiz, Abigail, Slaney, Claire, Garnham, Julie, Ruzickova, Martina, Calkin, Cynthia V, O'Donovan, Claire, Hajek, Tomas, Alda, Martin

“…Objective This study aimed to examine differences in the clinical presentation of very‐early‐onset (VEO) and early‐onset (EO) bipolar disorder (BD) not fully…”
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Repeated Erythromycin/Codeine-Induced Psychotic Mania by MANCHIA, Mirko, ALDA, Martin, CALKIN, Cynthia V

“…Mania is generally associated with bipolar disorder; however, it can be iatrogenic. For instance, antibiotics and corticosteroids can cause manic symptoms…”
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Certain eating disorders may be a neuropsychiatric manifestation of PANDAS: case report by Calkin, Cynthia V, Carandang, Carlo G

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Chronotype and cellular circadian rhythms predict the clinical response to lithium maintenance treatment in patients with bipolar disorder by McCarthy, Michael J, Wei, Heather, Nievergelt, Caroline M, Stautland, Andrea, Maihofer, Adam X, Welsh, David K, Shilling, Paul, Alda, Martin, Alliey-Rodriguez, Ney, Anand, Amit, Andreasson, Ole A, Balaraman, Yokesh, Berrettini, Wade H, Bertram, Holli, Brennand, Kristen J, Calabrese, Joseph R, Calkin, Cynthia V, Claasen, Ana, Conroy, Clara, Coryell, William H, Craig, David W, D'Arcangelo, Nicole, Demodena, Anna, Djurovic, Srdjan, Feeder, Scott, Fisher, Carrie, Frazier, Nicole, Frye, Mark A, Gage, Fred H, Gao, Keming, Garnham, Julie, Gershon, Elliot S, Glazer, Kara, Goes, Fernando, Goto, Toyomi, Harrington, Gloria, Jakobsen, Petter, Kamali, Masoud, Karberg, Elizabeth, Kelly, Marisa, Leckband, Susan G, Lohoff, Falk, McInnis, Melvin G, Mondimore, Francis, Morken, Gunnar, Nurnberger, John I, Obral, Sarah, Oedegaard, Ketil J, Ortiz, Abigail, Ritchey, Megan, Ryan, Kelly, Schinagle, Martha, Schoeyen, Helle, Schwebel, Candice, Shaw, Martha, Shekhtman, Tatyana, Slaney, Claire, Stapp, Emma, Szelinger, Szabolcs, Tarwater, Bruce, Zandi, Peter P, Kelsoe, John R

“…Bipolar disorder (BD) is a serious mood disorder associated with circadian rhythm abnormalities. Risk for BD is genetically encoded and overlaps with systems…”
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Focal adhesion is associated with lithium response in bipolar disorder: evidence from a network-based multi-omics analysis by Niemsiri, Vipavee, Rosenthal, Sara Brin, Nievergelt, Caroline M., Maihofer, Adam X., Marchetto, Maria C., Santos, Renata, Shekhtman, Tatyana, Alliey-Rodriguez, Ney, Anand, Amit, Balaraman, Yokesh, Berrettini, Wade H., Bertram, Holli, Burdick, Katherine E., Calabrese, Joseph R., Calkin, Cynthia V., Conroy, Carla, Coryell, William H., DeModena, Anna, Eyler, Lisa T., Feeder, Scott, Fisher, Carrie, Frazier, Nicole, Frye, Mark A., Gao, Keming, Garnham, Julie, Gershon, Elliot S., Goes, Fernando S., Goto, Toyomi, Harrington, Gloria J., Jakobsen, Petter, Kamali, Masoud, Kelly, Marisa, Leckband, Susan G., Lohoff, Falk W., McCarthy, Michael J., McInnis, Melvin G., Craig, David, Millett, Caitlin E., Mondimore, Francis, Morken, Gunnar, Nurnberger, John I., Donovan, Claire O’, Øedegaard, Ketil J., Ryan, Kelly, Schinagle, Martha, Shilling, Paul D., Slaney, Claire, Stapp, Emma K., Stautland, Andrea, Tarwater, Bruce, Zandi, Peter P., Alda, Martin, Fisch, Kathleen M., Gage, Fred H., Kelsoe, John R.

“…Lithium (Li) is one of the most effective drugs for treating bipolar disorder (BD), however, there is presently no way to predict response to guide treatment…”
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Clinical predictors of non‐response to lithium treatment in the Pharmacogenomics of Bipolar Disorder (PGBD) study by Lin, Yian, Maihofer, Adam X., Stapp, Emma, Ritchey, Megan, Alliey‐Rodriguez, Ney, Anand, Amit, Balaraman, Yokesh, Berrettini, Wade H., Bertram, Holli, Bhattacharjee, Abesh, Calkin, Cynthia V., Conroy, Carla, Coryell, William, D'Arcangelo, Nicole, DeModena, Anna, Biernacka, Joanna M., Fisher, Carrie, Frazier, Nicole, Frye, Mark, Gao, Keming, Garnham, Julie, Gershon, Elliot, Glazer, Kara, Goes, Fernando S., Goto, Toyomi, Karberg, Elizabeth, Harrington, Gloria, Jakobsen, Petter, Kamali, Masoud, Kelly, Marisa, Leckband, Susan G., Lohoff, Falk W., Stautland, Andrea, McCarthy, Michael J., McInnis, Melvin G., Mondimore, Francis, Morken, Gunnar, Nurnberger, John I., Oedegaard, Ketil J., Syrstad, Vigdis Elin Giever, Ryan, Kelly, Schinagle, Martha, Schoeyen, Helle, Andreassen, Ole A., Shaw, Marth, Shilling, Paul D., Slaney, Claire, Tarwater, Bruce, Calabrese, Joseph R., Alda, Martin, Nievergelt, Caroline M., Zandi, Peter P., Kelsoe, John R.

“…Background Lithium is regarded as a first‐line treatment for bipolar disorder (BD), but partial response and non‐response commonly occurs. There exists a need…”
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Correction of depression‐associated circadian rhythm abnormalities is associated with lithium response in bipolar disorder by Federoff, Monica, McCarthy, Michael J., Anand, Amit, Berrettini, Wade H., Bertram, Holli, Bhattacharjee, Abesh, Calkin, Cynthia V., Conroy, Carla, Coryell, William H., D'Arcangelo, Nicole, DeModena, Anna, Fisher, Carrie, Feeder, Scott, Frazier, Nicole, Frye, Mark A., Gao, Keming, Garnham, Julie, Gershon, Elliot S., Alliey‐Rodriguez, Ney, Glazer, Kara, Goes, Fernando, Karberg, Toyomi, Harrington, Gloria, Jakobsen, Petter, Kamali, Masoud, Kelly, Marisa, Leckband, Susan G., Lohoff, Falk, Maihofer, Adam X., McInnis, Melvin G., Mondimore, Francis, Morken, Gunnar, Nurnberger, John I., Oedegaard, Ketil J., Ritchey, Megan, Ryan, Kelly, Schinagle, Martha, Schoeyen, Helle, Schwebel, Candice, Shaw, Martha, Shilling, Paul D., Slaney, Claire, Stautland, Andrea, Tarwater, Bruce, Calabrese, Joseph R., Alda, Martin, Nievergelt, Caroline M., Zandi, Peter P., Kelsoe, John R.

“…Background Bipolar disorder (BD) is characterized by episodes of depression and mania and disrupted circadian rhythms. Lithium is an effective therapy for BD,…”
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The Pharmacogenomics of Bipolar Disorder study (PGBD): identification of genes for lithium response in a prospective sample by Oedegaard, Ketil J, Alda, Martin, Anand, Anit, Andreassen, Ole A, Balaraman, Yokesh, Berrettini, Wade H, Bhattacharjee, Abesh, Brennand, Kristen J, Burdick, Katherine E, Calabrese, Joseph R, Calkin, Cynthia V, Claasen, Ana, Coryell, William H, Craig, David, DeModena, Anna, Frye, Mark, Gage, Fred H, Gao, Keming, Garnham, Julie, Gershon, Elliot, Jakobsen, Petter, Leckband, Susan G, McCarthy, Michael J, McInnis, Melvin G, Maihofer, Adam X, Mertens, Jerome, Morken, Gunnar, Nievergelt, Caroline M, Nurnberger, John, Pham, Son, Schoeyen, Helle, Shekhtman, Tatyana, Shilling, Paul D, Szelinger, Szabolcs, Tarwater, Bruce, Yao, Jun, Zandi, Peter P, Kelsoe, John R

“…Bipolar disorder is a serious and common psychiatric disorder characterized by manic and depressive mood switches and a relapsing and remitting course. The…”
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Insulin resistance and outcome in bipolardisorder by Calkin, Cynthia V, Ruzickova Martina, Uher Rudolf, Hajek, Tomas, Slaney, Claire M, Garnham, Julie S, Claire, O'Donovan M, Martin, Alda

“…BackgroundLittle is known about the impact of insulin resistance on bipolardisorder.AimsTo examine the relationships between insulin resistance, type 2…”
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Assessment of Response to Lithium Maintenance Treatment in Bipolar Disorder: A Consortium on Lithium Genetics by Manchia, Mirko, Adli, Mazda, Akula, Nirmala, Ardau, Raffaella, Aubry, Jean-Michel, Backlund, Lena, Banzato, Claudio EM, Baune, Bernhard T, Bellivier, Frank, Bengesser, Susanne, Biernacka, Joanna M, Brichant-Petitjean, Clara, Bui, Elise, Calkin, Cynthia V, Cheng, Andrew Tai Ann, Chillotti, Caterina, Cichon, Sven, Clark, Scott, Czerski, Piotr M, Dantas, Clarissa, Zompo, Maria Del, DePaulo, J. Raymond, Detera-Wadleigh, Sevilla D, Etain, Bruno, Falkai, Peter, Frisén, Louise, Frye, Mark A, Fullerton, Jan, Gard, Sébastien, Garnham, Julie, Goes, Fernando S, Grof, Paul, Gruber, Oliver, Hashimoto, Ryota, Hauser, Joanna, Heilbronner, Urs, Hoban, Rebecca, Hou, Liping, Jamain, Stéphane, Kahn, Jean-Pierre, Kassem, Layla, Kato, Tadafumi, Kelsoe, John R, Kittel-Schneider, Sarah, Kliwicki, Sebastian, Kuo, Po-Hsiu, Kusumi, Ichiro, Laje, Gonzalo, Lavebratt, Catharina, Leboyer, Marion, Leckband, Susan G, López Jaramillo, Carlos A, Maj, Mario, Malafosse, Alain, Martinsson, Lina, Masui, Takuya, Mitchell, Philip B, Mondimore, Frank, Monteleone, Palmiero, Nallet, Audrey, Neuner, Maria, Novák, Tomás, O'Donovan, Claire, Ösby, Urban, Ozaki, Norio, Perlis, Roy H, Pfennig, Andrea, Potash, James B, Reich-Erkelenz, Daniela, Reif, Andreas, Reininghaus, Eva, Richardson, Sara, Rouleau, Guy A, Rybakowski, Janusz K, Schalling, Martin, Schofield, Peter R, Schubert, Oliver K, Schweizer, Barbara, Seemüller, Florian, Grigoroiu-Serbanescu, Maria, Severino, Giovanni, Seymour, Lisa R, Slaney, Claire, Smoller, Jordan W, Squassina, Alessio, Stamm, Thomas, Steele, Jo, Stopkova, Pavla, Tighe, Sarah K, Tortorella, Alfonso, Turecki, Gustavo, Wray, Naomi R, Wright, Adam, Zandi, Peter P, Zilles, David, Bauer, Michael, Rietschel, Marcella, McMahon, Francis J, Schulze, Thomas G, Alda, Martin

“…Objective The assessment of response to lithium maintenance treatment in bipolar disorder (BD) is complicated by variable length of treatment, unpredictable…”
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