Search Results - "Calis, Unsal"

New (arylalkyl)azole derivatives showing anticonvulsant effects could have VGSC and/or GABAAR affinity according to molecular modeling studies by Sari, Suat, Karakurt, Arzu, Uslu, Harun, Kaynak, F. Betül, Çalış, Ünsal, Dalkara, Sevim

“…(Arylalkyl)azoles (AAAs) emerged as a novel class of antiepileptic agents with the invention of nafimidone and denzimol. Several AAA derivatives with potent…”
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Design, synthesis and in vivo/in vitro screening of novel chlorokojic acid derivatives by Karakaya, Gülşah, Aytemir, Mutlu Dilsiz, Özçelik, Berrin, Calış, Ünsal

“…A series of novel Mannich bases of chlorokojic acid (2-chloromethyl-5-hydroxy-4H-pyran-4-one) were synthesized and their biological activities were…”
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Synthesis and Evaluation of Anticonvulsant and Antimicrobial Activities of 3-Hydroxy-6-methyl-2-substituted 4H-Pyran-4-one Derivatives by Aytemir, Mutlu Dilsiz, Çaliş, Ünsal, Özalp, Meral

“…In this study, thirteen 3‐hydroxy‐6‐methyl‐2‐substituted 4H‐pyran‐4‐one derivatives were synthesized for the evaluation of their potential anticonvulsant…”
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Anticonvulsant and Neurotoxicity Evaluation of Some Novel Kojic Acids and Allomaltol Derivatives by Aytemir, Mutlu Dilsiz, Çalış, Ünsal

“…A series of new 3‐hydroxy‐6‐hydroxymethyl/methyl‐2‐substituted 4H‐pyran‐4‐ones were synthesized and prepared by the reaction of kojic acid or allomaltol with…”
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Synthesis, anticonvulsant and antimicrobial activities of some new [1-(2-naphthyl)-2-(pyrazol-1-yl)ethanone]oxime ethers by Özdemir, Zeynep, Karakurt, Arzu, Çali, Ünsal, Günal, Selami, Işik, Şamil, Şahin, Z Sibel, Dalkara, Sevim

“…In this study, 12 new oxime ether derivatives, which were expected to show anticonvulsant and antimicrobial activities, were synthesized. Oxime ether…”
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Synthesis of some novel 1-(2-naphthyl)-2-(imidazol-1-yl)ethanone oxime ester derivatives and evaluation of their anticonvulsant activity by Karakurt, Arzu, Alagöz, Mehmet A., Sayoğlu, Burcu, Çalış, Ünsal, Dalkara, Sevim

“…Twenty-three new oxime ester derivatives of nafimidone were synthesized with the prospect of potential anticonvulsant activities. MES and ScM tests were…”
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Synthesis and studies on antidepressant and anticonvulsant activities of some 3-(2-furyl)-pyrazoline derivatives by Özdemir, Zuhal, Kandilci, H. Burak, Gümüşel, Bülent, Çalış, Ünsal, Bilgin, A. Altan

“…Twelve 1-phenyl-, 1-thiocarbamoyl- and 1- N-substituted thiocarbamoyl-3-(2-furyl)-5-phenyl/(2-furyl)-2-pyrazoline derivatives were synthesized. The chemical…”
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Synthesis and anticonvulsant evaluation of some novel (thio)semicarbazone derivatives of arylalkylimidazole by Çaliş, Ünsal, SeptioğluEbubekir, Septioğlu, Aytemir, Mutlu Dilsiz

“…Abstract A number of novel 2-(1 H -imidazole-1-yl)-1-aryl-substituted ethane-1-one N-substi-tuted phenyl(thio)semicarbazones (1-14) were synthesized to test…”
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Synthesis and anticonvulsant activity of some N-(benzoyl)glycinanilide derivatives by Soyer, Zeynep, Akgul, Ozlem, Tarikogullari, Ayse H., Calis, Unsal

“…Glycine is a major inhibitory neurotransmitter and recent studies have shown that certain lipophilic glycine derivatives demonstrate anticonvulsant activity in…”
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Synthesis and Studies on Antidepressant and Anticonvulsant Activities of Some 3-(2-Thienyl)pyrazoline Derivatives by Ozdemir, Zuhal, Kandilci, H. Burak, Gumusel, Bulent, Calis, Unsal, Bilgin, A. Altan

“…In this study, the synthesis of twelve 3‐(2‐thienyl)pyrazoline derivatives are described. The structures of all compounds were confirmed by UV, IR, 1H‐NMR,…”
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2-[6-(3-Chlorophenyl)-2,4-dioxoperhydropyrimidin-3-yl]ethyl morpholine-4-carbodithioate by KÖYSAL, Yavuz, ISIK, Samil, SEPTIOGLU, Ebubekir, CALIS, Ünsal

“…In the title compound, C 17 H 20 ClN 3 O 3 S 2 , the hexahydropyrimidine ring is puckered, the total puckering amplitude Q T being 0.41 (1) Å. The morpholine…”
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Synthesis and anticonvulsant activity of new kojic acid derivatives by Aytemir, Mutlu Dilsiz, Septioğlu, Ebubekir, Çaliş, Ünsal

“…Abstract A series of new 3-hydroxy-6-hydroxy-methyl-2-substituted 4 H -pyran-4-one derivatives were synthesized as potential anticonvulsant compounds. Mannich…”
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Synthesis of and Pharmacological Studies on the Antidepressant and Anticonvulsant Activities of Some 1,3,5-Trisubstituted Pyrazolines by Ruhoğlu, Ozan, Özdemir, Zuhal, Çaliş, Ünsal, Gümüşel, Bülent, Bilgin, Abdullah Altan

“…Summary Eighteen 1-phenyl-, 1-thiocarbamoyl-and 1-N-substitutedthiocarbamoyl-3-phenyl-5-heteroaryl-2-pyrazoline derivatives were synthesized and tested for…”
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Synthesis and Anticonvulsant Activity of Some New Hexahydropyrimidine-2,4-dione Derivatives by Septioğlu, Ebubekir, Aytemir, Mutlu Dilsiz, Çalış, Ünsal

“…Summary In this study, twelve new hexahydropyrimidine-2,4-dione derivatives were synthesized and screened for their anticonvulsant activities. All the…”
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Synthesis and Anticonvulsant Activity of Some New Dioxolane Derivatives by Özkanlı, Fügen, Güney, Ahu, Çalış, Ünsal, Uzbay, Tayfun

“…Summary In this study, ten 2-acetylnaphthalene derivatives with a dioxolane structure were synthesized and screened for their anticonvulsant activities…”
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Synthesis and Antimicrobial Activity Evaluation of Some New Adamantane Derivatives by Ünsal, Çalısş, Yarıma, Mine, Köksala, Mericç, Özalpb, Meral

“…Summary In this study, some new Schiff bases were synthesized as antimicrobial agents using benzaldehyde derivatives and 1-or 2-aminoadamantane. The structures…”
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Evaluation of Anticonvulsant Activities of Bis(3-aryl-3-oxo-propyl)ethylamine Hydrochlorides and 4-Aryl-3-arylcarbo-nyl-1-ethyl-4-piperidinol Hydrochlorides by Gul, Halise Inci, Calis, Unsal, Ozturk, Zeynep, Tutar, Emre, Calikiran, Leyla

“…Abstract Bis-Mannich bases, bis(3-aryl-3-oxo-propyljethylamlne hydrochlorides 1-4, and their corresponding structural and non-classical isomers,…”
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Evaluation of anticonvulsant activities of bis (3 -aryl -3 -oxo -propyl )ethylamine hydrochlorides and 4-aryl-3-arylcarbonyl -1-ethyl -4 -piperidinol hydrochlorides by HALISE INCI GULL, CALLS, Unsal, OZTURK, Zevnep, TUTAR, Emre, CALIKIRAN, Levla

“…Bis-Mannich bases, bis(3-aryl-3-oxopropyl)ethylamine hydrochlorides 1-4, and their corresponding structural and non-classical isomers,…”
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Synthesis of Some Mono-Mannich Bases and Corresponding Azine Derivatives and Evaluation of their Anticonvulsant Activity by Gul, Halise Inci, Calis, Unsal, Vepsalainen, Jouko

“…Summary Mono-Mannich bases, 3-amino-1-aryl-1-propanone hydrochlorides (Ig1-Ig4), and their corresponding azine derivatives,…”
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Evaluation of the Analgesic and Anti-inflammatory Activities of Some Thiazolo[4,5-d]pyrimidines by Balkan, Ayla, Gören, Zafer, Urgun, Hüsne, Çalιş, Ünsal, Çakar, A. Nur, Atilla, Pergin, Uzbay, Tayfun

“…Summary Some thiazolo[4,5-d]pyrimidine-7(6H)-one derivatives were evaluated in vivo for their analgesic and anti-inflammatory activities. The results were…”
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