Search Results - "Calis, Karim"

Antibiotic prophylaxis for elective hysterectomy by Ayeleke, Reuben Olugbenga, Mourad, Selma, Marjoribanks, Jane, Calis, Karim A, Jordan, Vanessa

“…Elective hysterectomy is commonly performed for benign gynaecological conditions. Hysterectomy can be performed abdominally, laparoscopically, or vaginally,…”
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Bone Mineral Density in Young Women With Primary Ovarian Insufficiency: Results of a Three-Year Randomized Controlled Trial of Physiological Transdermal Estradiol and Testosterone Replacement by Popat, Vaishali B, Calis, Karim A, Kalantaridou, Sophia N, Vanderhoof, Vien H, Koziol, Deloris, Troendle, James F, Reynolds, James C, Nelson, Lawrence M

“…Context: Women with primary ovarian insufficiency have significantly lower serum estradiol and T levels compared with regularly menstruating women. They also…”
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Effects of Metformin on Body Weight and Body Composition in Obese Insulin-Resistant Children: A Randomized Clinical Trial by YANOVSKI, Jack A, KRAKOFF, Jonathan, SALAITA, Christine G, MCDUFFIE, Jennifer R, KOZLOSKY, Merel, SEBRING, Nancy G, REYNOLDS, James C, BRADY, Sheila M, CALIS, Karim A

“…Metformin can decrease adiposity and ameliorate obesity-related comorbid conditions, including abnormalities in glucose homeostasis in adolescents, but there…”
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Bone Mineral Density in Estrogen-Deficient Young Women by Popat, Vaishali B., Calis, Karim A., Vanderhoof, Vien H., Cizza, Giovanni, Reynolds, James C., Sebring, Nancy, Troendle, James F., Nelson, Lawrence M.

“…Context: Osteoporosis primarily affects postmenopausal women. However, young women with estrogen deficiency also are at increased risk for low bone density…”
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Enhancing the Scientific Integrity and Safety of Clinical Trials: Recommendations for Data Monitoring Committees by Lewis, Roger J, Calis, Karim A, DeMets, David L

“…Lewis et al talk about the risks of participating in a clinical trial which cannot be predicted with certainty at the time of trial design, especially when…”
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Orthopedic Complications of Overweight in Children and Adolescents by Taylor, Erica D, Theim, Kelly R, Mirch, Margaret C, Ghorbani, Samareh, Tanofsky-Kraff, Marian, Adler-Wailes, Diane C, Brady, Sheila, Reynolds, James C, Calis, Karim A, Yanovski, Jack A

“…Few studies have quantified the prevalence of weight-related orthopedic conditions in otherwise healthy overweight children. The goal of the present…”
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A pharmacokinetic and pharmacodynamic study of delayed- and extended-release hydrocortisone (ChronocortTM) vs. conventional hydrocortisone (CortefTM) in the treatment of congenital adrenal hyperplasia by Verma, Somya, VanRyzin, Carol, Sinaii, Ninet, Kim, Mimi S., Nieman, Lynnette K., Ravindran, Shayna, Calis, Karim A., Arlt, Wiebke, Ross, Richard J., Merke, Deborah P.

“…Summary Objective  Existing glucocorticoid treatment for congenital adrenal hyperplasia (CAH) is suboptimal and nonphysiological. We compared hormonal profiles…”
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Recommendations for data monitoring committees from the Clinical Trials Transformation Initiative by Calis, Karim A, Archdeacon, Patrick, Bain, Raymond, DeMets, David, Donohue, Miriam, Elzarrad, M Khair, Forrest, Annemarie, McEachern, John, Pencina, Michael J, Perlmutter, Jane, Lewis, Roger J

“…Background/aims Use of data monitoring committees to oversee clinical trials was first proposed nearly 50 years ago. Since then, data monitoring committee use…”
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Endothelial Function, But Not Carotid Intima-Media Thickness, Is Affected Early in Menopause and Is Associated with Severity of Hot Flushes by Bechlioulis, Aris, Kalantaridou, Sophia N, Naka, Katerina K, Chatzikyriakidou, Anthoula, Calis, Karim A, Makrigiannakis, Antonis, Papanikolaou, Odysseas, Kaponis, Apostolos, Katsouras, Christos, Georgiou, Ioannis, Chrousos, George P, Michalis, Lampros K

“…Context: The effect of early menopause on indices of vascular function has been little studied. Objective: The objective of the study was to investigate the…”
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Effects of SLC22A1 Polymorphisms on Metformin‐Induced Reductions in Adiposity and Metformin Pharmacokinetics in Obese Children With Insulin Resistance by Sam, Wai Johnn, Roza, Orsolya, Hon, Yuen Yi, Alfaro, Raul M., Calis, Karim A., Reynolds, James C., Yanovski, Jack A.

“…Steady‐state population pharmacokinetics of a noncommercial immediate‐release metformin (hydrochloride) drug product were characterized in 28 severely obese…”
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Technical details influence the diagnostic accuracy of the 1 μg ACTH stimulation test by Wade, Matthew, Baid, Smita, Calis, Karim, Raff, Hershel, Sinaii, Ninet, Nieman, Lynnette

“…ObjectiveTo examine the factors causing inadequate cortisol responses to the 1 μg ACTH stimulation test.DesignRandom test assignment (by age and gender) at…”
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A placebo-controlled trial of simvastatin therapy in Smith-Lemli-Opitz syndrome by Wassif, Christopher A., Kratz, Lisa, Sparks, Susan E., Wheeler, Courtney, Bianconi, Simona, Gropman, Andrea, Calis, Karim A., Kelley, Richard I., Tierney, Elaine, Porter, Forbes D.

“…Smith-Lemli-Opitz syndrome (SLOS) is a multiple malformation/cognitive impairment syndrome characterized by the accumulation of 7-dehydrocholesterol, a…”
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Understanding the functions and operations of data monitoring committees: Survey and focus group findings by Calis, Karim A, Archdeacon, Patrick, Bain, Raymond P, Forrest, Annemarie, Perlmutter, Jane, DeMets, David L

“…Background: The use of data monitoring committees in the conduct of clinical trials has increased and evolved, but there is a lack of published information on…”
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The menstrual cycle: a biological marker of general health in adolescents by Popat, Vaishali B, Prodanov, Tamara, Calis, Karim A, Nelson, Lawrence M

“…Menstruation is the cyclic, orderly sloughing of the uterine lining on account of the interactions of hormones produced by the hypothalamus, pituitary, and…”
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Effect of the insulin sensitizers metformin and pioglitazone on endothelial function in young women with polycystic ovary syndrome: a prospective randomized study by Naka, Katerina K., M.D., Ph.D, Kalantaridou, Sophia N., M.D, Kravariti, Maria, M.D, Bechlioulis, Aris, M.D, Kazakos, Nikolaos, M.D, Calis, Karim A., Pharm.D., M.P.H, Makrigiannakis, Antonis, M.D., Ph.D, Katsouras, Christos S., M.D, Chrousos, George P., M.D, Tsatsoulis, Agathocles, M.D., Ph.D, Michalis, Lampros K., M.D

“…Objective To compare the effect of two different insulin sensitizers, metformin and pioglitazone, on endothelial function in women with polycystic ovary…”
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Data monitoring committees: Promoting best practices to address emerging challenges by Fleming, Thomas R, DeMets, David L, Roe, Matthew T, Wittes, Janet, Calis, Karim A, Vora, Amit N, Meisel, Alan, Bain, Raymond P, Konstam, Marvin A, Pencina, Michael J, Gordon, David J, Mahaffey, Kenneth W, Hennekens, Charles H, Neaton, James D, Pearson, Gail D, Andersson, Tomas LG, Pfeffer, Marc A, Ellenberg, Susan S

“…Background and Purpose: Data monitoring committees are responsible for safeguarding the interests of study participants and assuring the integrity and…”
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Depression in Women with Spontaneous 46, XX Primary Ovarian Insufficiency by Schmidt, Peter J, Luff, Jamie A, Haq, Nazli A, Vanderhoof, Vien H, Koziol, Deloris E, Calis, Karim A, Rubinow, David R, Nelson, Lawrence M

“…Primary ovarian insufficiency (POI) is associated with increased risk for depression, episodes of which frequently occur after the onset of menstrual…”
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A prospective evaluation of antral follicle function in women with 46,XX spontaneous primary ovarian insufficiency by Hubayter, Ziad R., M.D., M.P.H, Popat, Vaishali, M.D., M.P.H, Vanderhoof, Vien H., R.N., M.H.A., C.R.N.P, Ndubizu, Obioma, M.D, Johnson, Diane, R.T., R.D.M.S, Mao, Edie, M.B., R.D.M.S., R.V.T, Calis, Karim A., Pharm.D., M.P.H, Troendle, James F., Ph.D, Nelson, Lawrence M., M.D

“…Objective To assess ovarian follicle function in women with 46,XX spontaneous primary ovarian insufficiency. Design Case–control with nested prospective…”
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Effects of Calcium Supplementation on Body Weight and Adiposity in Overweight and Obese Adults: A Randomized Trial by YANOVSKI, Jack A, PARIKH, Shamik J, YANOFF, Lisa B, DENKINGER, Blakeley I, CALIS, Karim A, REYNOLDS, James C, SEBRING, Nancy G, MCHUGH, Teresa

“…Some data suggest that increasing calcium intake may help prevent weight gain. To test the hypothesis that calcium supplementation can prevent weight gain in…”
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Sexual function in young women with spontaneous 46,XX primary ovarian insufficiency by Kalantaridou, Sophia N., M.D., Ph.D, Vanderhoof, Vien H., C.R.N.P., M.H.A, Calis, Karim A., Pharm.D., M.P.H, Corrigan, Emily C., M.D, Troendle, James F., Ph.D, Nelson, Lawrence M., M.D

“…Objective To assess sexual function in women with spontaneous 46,XX primary ovarian insufficiency after at least 3 months of a standardized hormone replacement…”
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