Search Results - "Cali, J J"
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A direct capture method for purification and detection of viral nucleic acid enables epidemiological surveillance of SARS-CoV-2
Published in The Science of the total environment (15-11-2021)“…Studies have demonstrated that SARS-CoV-2 RNA can be detected in the feces of infected individuals. This finding spurred investigation into using…”
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Monitoring phosphorylation and acetylation of CRISPR-mediated HiBiT-tagged endogenous proteins
Published in Scientific reports (25-01-2024)“…Intracellular pathways transduce signals through changes in post-translational modifications (PTMs) of effector proteins. Among the approaches used to monitor…”
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3
Keeping weight off: Mindfulness-Based Stress Reduction alters amygdala functional connectivity during weight loss maintenance in a randomized control trial
Published in PloS one (11-01-2021)“…Obesity is associated with significant comorbidities and financial costs. While behavioral interventions produce clinically meaningful weight loss, weight loss…”
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4
Micropatterning biomineralization with immobilized mother of pearl proteins
Published in Scientific reports (25-01-2021)“…In response to the drawbacks of autograft donor-site morbidity and bone morphogenetic protein type 2 (BMP2) carcinogenesis and ectopic bone formation, there…”
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5
Validation of a HTS-amenable assay to detect drug-induced mitochondrial toxicity in the absence and presence of cell death
Published in Toxicology in vitro (01-09-2013)“…•Assess drug-induced mitochondrial dysfunction and cell death simultaneously.•Identify mitochondrial toxicity and multifactorial toxicity after only 2h.•The…”
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6
Type VIII adenylyl cyclase in rat beta cells: coincidence signal detector/generator for glucose and GLP-1
Published in Diabetologia (01-10-2003)“…The secretory function of pancreatic beta cells is synergistically stimulated by two signalling pathways which mediate the effects of nutrients and hormones…”
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7
Cell-based, bioluminescent assay for monitoring the interaction between PCSK9 and the LDL receptor
Published in Journal of lipid research (01-08-2017)“…Monitoring the expression of cell-surface receptors, their interaction with extracellular ligands, and their fate upon ligand binding is important for…”
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8
Altered cytotoxicity of ROS-inducing compounds by sodium pyruvate in cell culture medium depends on the location of ROS generation
Published in SpringerPlus (17-06-2015)“…Induction of oxidative stress by drugs and other xenobiotics is an important mechanism of cytotoxicity. However, in vitro studies on the relationship between…”
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9
Type VIII adenylyl cyclase. A Ca2+/calmodulin-stimulated enzyme expressed in discrete regions of rat brain
Published in The Journal of biological chemistry (22-04-1994)“…A cDNA that encodes type VIII adenylyl cyclase has been isolated from two rat brain libraries. The open reading frame encodes a 1248-amino acid protein…”
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10
Partial Decay of Thiamine Signal Transduction Pathway Alters Growth Properties of Candida glabrata
Published in PloS one (25-03-2016)“…The phosphorylated form of thiamine (Vitamin B1), thiamine pyrophosphate (TPP) is essential for the metabolism of amino acids and carbohydrates in all…”
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11
A million-year record of fire in sub-Saharan Africa
Published in Nature (London) (20-08-1998)“…Biomass burning today constitutes approximately one-third of annual anthropogenic CO2 emissions, and there is a sound theoretical base for expecting…”
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12
Proluciferin Acetals as Bioluminogenic Substrates for Cytochrome P450 Activity and Probes for CYP3A Inhibition
Published in Drug metabolism and disposition (01-12-2011)“…Cytochrome P450 (P450) assays use probe substrates to interrogate the influence of new chemical entities toward P450 enzymes. We report the synthesis and study…”
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13
N-Alkylated 6′-Aminoluciferins Are Bioluminescent Substrates for Ultra-Glo and QuantiLum Luciferase: New Potential Scaffolds for Bioluminescent Assays
Published in Biochemistry (Easton) (30-09-2008)“…A set of 6′-alkylated aminoluciferins are shown to be bioluminescent substrates for Ultra-Glo and QuantiLum luciferases. These studies demonstrate that both…”
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14
Altered neural networks and cognition in a hereditary colon cancer
Published in IBRO neuroscience reports (01-12-2021)“…Familial Adenomatous Polyposis (FAP) is an autosomal dominant disorder caused by mutation of the APC gene presenting with numerous colorectal adenomatous…”
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ASSESSING THE RELIABILITY AND THE ACCURACY OF ATTITUDE EXTRACTED FROM VISUAL ODOMETRY FOR LIDAR DATA GEOREFERENCING
Published in International archives of the photogrammetry, remote sensing and spatial information sciences. (01-01-2017)“…Airborne LiDAR systems require the use of Direct Georeferencing (DG) in order to compute the coordinates of the surveyed point in the mapping frame. An UAV…”
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Mutations in the bile acid biosynthetic enzyme sterol 27-hydroxylase underlie cerebrotendinous xanthomatosis
Published in The Journal of biological chemistry (25-04-1991)“…The sterol storage disorder cerebrotendinous xanthomatosis (CTX) is characterized by abnormal deposition of cholesterol and cholestanol in multiple tissues…”
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Molecular imaging of cytochrome P450 activity in mice
Published in Pharmacological research (01-05-2012)“…Detailed knowledge of drug metabolism is relevant information provided by preclinical drug development research. Oxidative enzymes such as those belonging to…”
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The utility of semi-automating multiplexed assays for ADME/Tox applications
Published in Combinatorial chemistry & high throughput screening (01-09-2011)“…ADME-Tox testing examines the effects of an organism, tissue or cell on a compound, as well as the effects that the compound has on an organism, tissue or…”
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INTEGRATION OF A STRAPDOWN GRAVIMETER SYSTEM IN AN AUTONOMOUS UNDERWATER VEHICLE
Published in International archives of the photogrammetry, remote sensing and spatial information sciences. (09-04-2015)“…We present a new mobile instrument for measuring dynamically the gravity vector and its gradients in underwater environment, named GRAVIMOB. Our instrument is…”
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Journal Article Conference Proceeding -
20
A bioluminescent assay for the sensitive detection of proteases
Published in BioTechniques (01-08-2011)“…A bioluminescent general protease assay was developed using a combination of five luminogenic peptide substrates. The peptide-conjugated luciferin substrates…”
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