Search Results - "Cali, Anna M G"

Effects of a Weight Management Program on Body Composition and Metabolic Parameters in Overweight Children: A Randomized Controlled Trial by Savoye, Mary, Shaw, Melissa, Dziura, James, Tamborlane, William V, Rose, Paulina, Guandalini, Cindy, Goldberg-Gell, Rachel, Burgert, Tania S, Cali, Anna M. G, Weiss, Ram, Caprio, Sonia

“…CONTEXT Pediatric obesity has escalated to epidemic proportions, leading to an array of comorbidities, including type 2 diabetes in youth. Since most…”
Get full text

Metabolic Abnormalities Underlying the Different Prediabetic Phenotypes in Obese Adolescents by Cali', Anna M. G., Bonadonna, Riccardo C., Trombetta, Maddalena, Weiss, Ram, Caprio, Sonia

“…Objective: The aim of this study was to define the metabolic abnormalities underlying the prediabetic status of isolated impaired fasting glucose (IFG),…”
Get full text

Glucose dysregulation and hepatic steatosis in obese adolescents: Is there a link? by Cali, Anna M.G., De Oliveira, Ana Mayra, Kim, Hyeonjin, Chen, Shu, Reyes‐Mugica, Miguel, Escalera, Sandra, Dziura, James, Taksali, Sara E., Kursawe, Romy, Shaw, Melissa, Savoye, Mary, Pierpont, Bridget, Constable, R. Todd, Caprio, Sonia

“…Fatty liver is increasingly common in obese adolescents. We determined its association with glucose dysregulation in 118 (37M/81F) obese adolescents of similar…”
Get full text

Obesity in Children and Adolescents by Cali, Anna M. G., Caprio, Sonia

“…Context: Although the prevalence rates of childhood obesity have seemingly been stable over the past few years, far too many children and adolescents are still…”
Get full text

More Similarities Than Differences Testing Insulin Glargine 300 Units/mL Versus Insulin Degludec 100 Units/mL in Insulin-Naive Type 2 Diabetes: The Randomized Head-to-Head BRIGHT Trial by Rosenstock, Julio, Cheng, Alice, Ritzel, Robert, Bosnyak, Zsolt, Devisme, Christine, Cali, Anna M G, Sieber, Jochen, Stella, Peter, Wang, Xiangling, Frías, Juan P, Roussel, Ronan, Bolli, Geremia B

“…To compare insulin glargine 300 units/mL (Gla-300) versus insulin degludec 100 units/mL (IDeg-100) in this first head-to-head randomized controlled trial…”
Get full text

High Visceral and Low Abdominal Subcutaneous Fat Stores in the Obese Adolescent : A Determinant of an Adverse Metabolic Phenotype by TAKSALI, Sara E, CAPRIO, Sonia, SHAW, Melissa, SEYAL, Aisha A, WEISS, Ram, DZIURA, James, DUFOUR, Sylvie, CALI, Anna M. G, GOODMAN, T. Robin, PAPADEMETRIS, Xenophon, BURGERT, Tania S, PIERPONT, Bridget M, SAVOYE, Mary

“…To explore whether an imbalance between the visceral and subcutaneous fat depots and a corresponding dysregulation of the adipokine milieu is associated with…”
Get full text

Cellularity and Adipogenic Profile of the Abdominal Subcutaneous Adipose Tissue From Obese Adolescents: Association With Insulin Resistance and Hepatic Steatosis by KURSAWE, Romy, ESZLINGER, Markus, CUSHMAN, Samuel W, SHERMAN, Arthur, CAPRIO, Sonia, NARAYAN, Deepak, LIU, Teresa, BAZUINE, Merlijn, CALI, Anna M. G, D'ADAMO, Ebe, SHAW, Melissa, PIERPONT, Bridget, SHULMAN, Gerald I

“…We explored whether the distribution of adipose cell size, the estimated total number of adipose cells, and the expression of adipogenic genes in subcutaneous…”
Get full text

The Diabetes Unmet Need with Basal Insulin Evaluation (DUNE) study in type 2 diabetes: Achieving HbA1c targets with basal insulin in a real‐world setting by Meneghini, Luigi F., Mauricio, Didac, Orsi, Emanuela, Lalic, Nebojsa M., Cali, Anna M.G., Westerbacka, Jukka, Stella, Peter, Candelas, DEA, Christophe, Pilorget, Valerie, Perfetti, Riccardo, Khunti, Kamlesh

“…Aims To describe in a real‐world setting the achievement of physician‐selected individualized HbA1c targets in individuals with type 2 diabetes, newly or…”
Get full text

Primary Defects in β-Cell Function Further Exacerbated by Worsening of Insulin Resistance Mark the Development of Impaired Glucose Tolerance in Obese Adolescents by Cali, Anna M.G, Man, Chiara Dalla, Cobelli, Claudio, Dziura, James, Seyal, Aisha, Shaw, Melissa, Allen, Karin, Chen, Shu, Caprio, Sonia

“…OBJECTIVE:--Impaired glucose tolerance (IGT) is a pre-diabetic state of increasing prevalence among obese adolescents. The purpose of this study was to…”
Get full text

Low Blood Glucose Index and Hypoglycaemia Risk: Insulin Glargine 300 U/mL Versus Insulin Glargine 100 U/mL in Type 2 Diabetes by Kovatchev, Boris, Meng, Zhaoling, Cali, Anna M. G., Perfetti, Riccardo, Breton, Marc D.

“…Introduction We examined differences in hypoglycaemia risk between insulin glargine 300 U/mL (Gla-300) and insulin glargine 100 U/mL (Gla-100) in individuals…”
Get full text

Adiponectin in Childhood and Adolescent Obesity and Its Association with Inflammatory Markers and Components of the Metabolic Syndrome by Winer, Jeffrey C., Zern, Tosca L., Taksali, Sara E., Dziura, James, Cali, Anna M. G., Wollschlager, Margaret, Seyal, Aisha A., Weiss, Ram, Burgert, Tania S., Caprio, Sonia

“…Context: Adiponectin levels are lower in obese children and adolescents, whereas markers of inflammation and proinflammatory cytokines are higher…”
Get full text

Variants in ARHGEF11, a Candidate Gene for the Linkage to Type 2 Diabetes on Chromosome 1q, Are Nominally Associated With Insulin Resistance and Type 2 Diabetes in Pima Indians by LIJUN MA, HANSON, Robert L, QUE, Lorem N, CALI, Anna M. G, MAO FU, MACK, Janel L, INFANTE, Aniello M, KOBES, Sayuko, SHULDINER, Alan R, BALER, Leslie J

“…Variants in ARHGEF11 , a Candidate Gene for the Linkage to Type 2 Diabetes on Chromosome 1q, Are Nominally Associated With Insulin Resistance and Type 2…”
Get full text

Ectopic fat deposition and the metabolic syndrome in obese children and adolescents by Cali, Anna M G, Caprio, Sonia

“…We examined the impact of varying degrees of obesity on the prevalence of the metabolic syndrome and its relation to ectopic fat deposition in a large,…”
Get more information

Central Role of Fatty Liver in the Pathogenesis of Insulin Resistance in Obese Adolescents by D'Adamo, Ebe, Cali, Anna M.G, Weiss, Ram, Santoro, Nicola, Pierpont, Bridget, Northrup, Veronika, Caprio, Sonia

“…OBJECTIVE: We evaluated the role of fatty liver in the alteration of insulin sensitivity and β-cell function in two groups of obese adolescents, differing in…”
Get full text

Interethnic differences in muscle, liver and abdominal fat partitioning in obese adolescents by Liska, David, Dufour, Sylvie, Zern, Tosca L, Taksali, Sara, Calí, Anna M G, Dziura, James, Shulman, Gerald I, Pierpont, Bridget M, Caprio, Sonia

“…The prevalence of insulin resistance and type 2 diabetes (T2D) in obese youth is rapidly increasing, especially in Hispanics and African Americans compared to…”
Get full text

A pragmatic randomized clinical trial of insulin glargine 300 U/mL vs first‐generation basal insulin analogues in insulin‐naïve adults with type 2 diabetes: 6‐month outcomes of the ACHIEVE Control study by Meneghini, Luigi F., Sullivan, Sean D., Oster, Gerry, Busch, Robert, Cali, Anna M. G., Dauchy, Arnaud, Gill, Jasvinder, Bailey, Timothy S.

“…Aims To compare the safety and efficacy of insulin glargine 300 U/mL (Gla‐300) versus first‐generation standard‐of‐care basal insulin analogues (SOC‐BI;…”
Get full text

Rare variants in single-minded 1 (SIM1) are associated with severe obesity by Ramachandrappa, Shwetha, Raimondo, Anne, Cali, Anna M G, Keogh, Julia M, Henning, Elana, Saeed, Sadia, Thompson, Amanda, Garg, Sumedha, Bochukova, Elena G, Brage, Soren, Trowse, Victoria, Wheeler, Eleanor, Sullivan, Adrienne E, Dattani, Mehul, Clayton, Peter E, Datta, Vipan, Datta, Vippan, Bruning, John B, Wareham, Nick J, O'Rahilly, Stephen, Peet, Daniel J, Barroso, Ines, Whitelaw, Murray L, Farooqi, I Sadaf

“…Single-minded 1 (SIM1) is a basic helix-loop-helix transcription factor involved in the development and function of the paraventricular nucleus of the…”
Get full text

Real-world outcomes of treatment with insulin glargine 300 U/mL versus standard-of-care in people with uncontrolled type 2 diabetes mellitus by Freemantle, Nick, Mauricio, Didac, Giaccari, Andrea, Bailey, Timothy, Roussel, Ronan, Franco, Denise, Berthou, Baptiste, Pilorget, Valerie, Westerbacka, Jukka, Bosnyak, Zsolt, Bonnemaire, Mireille, Cali, Anna M. G., Nguyên-Pascal, My-Liên, Penfornis, Alfred, Perez-Maraver, Manuel, Seufert, Jochen, Sullivan, Sean D., Wilding, John, Wysham, Carol, Davies, Melanie

“…To compare real-world outcomes with newer (insulin glargine 300 U/mL; Gla-300) versus standard of care (SoC) basal insulins (BIs) in the REACH (insulin-naïve;…”
Get full text

Glycaemic control and hypoglycaemia benefits with insulin glargine 300 U/mL extend to people with type 2 diabetes and mild‐to‐moderate renal impairment by Javier Escalada, F., Halimi, Serge, Senior, Peter A., Bonnemaire, Mireille, Cali, Anna M. G., Melas‐Melt, Lydie, Karalliedde, Janaka, Ritzel, Robert A.

“…Aim To investigate the impact of renal function on the safety and efficacy of insulin glargine 300 U/mL (Gla‐300) and insulin glargine 100 U/mL (Gla‐100)…”
Get full text

A post‐hoc pooled analysis to evaluate the risk of hypoglycaemia with insulin glargine 300 U/mL (Gla‐300) versus 100 U/mL (Gla‐100) over wider nocturnal windows in individuals with type 2 diabetes on a basal‐only insulin regimen by Bolli, Geremia B., Wysham, Carol, Fisher, Miles, Chevalier, Soazig, Cali, Anna M. G., Leroy, Bruno, Riddle, Matthew C.

“…The EDITION trials in type 2 diabetes demonstrated comparable glycaemic control with less nocturnal and anytime (24‐hour) hypoglycaemia for insulin glargine…”
Get full text