Search Results - "Calhoun, Jacob"

Orthogonal pre-use and post-use efficiency testing for single-use anion exchange chromatography by Hester, Jonathan F., Lu, Xinran, Calhoun, Jacob D., Hochstein, Rebecca A., Olson, Eric J.

“…•A pre-use test characterizes integrity and capacity of single-use AEX devices.•In situ pre- and post-use testing identifies both mechanical and chemical…”
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Lenvatinib Plus Anti-PD-1 Combination Therapy for Advanced Cancers: Defining Mechanisms of Resistance in an Inducible Transgenic Model of Thyroid Cancer by Bertol, Bruna C, Bales, Elise S, Calhoun, Jacob D, Mayberry, Alanna, Ledezma, Melissa L, Sams, Sharon B, Orlicky, David J, Donadi, Eduardo A, Haugen, Bryan R, French, Jena D

“…Combination therapy with lenvatinib plus programmed death-1 (PD-1) immune checkpoint blockades (ICBs) is under investigation in many solid tumors, including…”
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Role of epidermal growth factor receptor inhibitor-induced interferon pathway signaling in the head and neck squamous cell carcinoma therapeutic response by Korpela, Sean P, Hinz, Trista K, Oweida, Ayman, Kim, Jihye, Calhoun, Jacob, Ferris, Robert, Nemenoff, Raphael A, Karam, Sana D, Clambey, Eric T, Heasley, Lynn E

“…Epidermal growth factor receptor (EGFR) is frequently amplified or overexpressed in head and neck squamous cell carcinoma (HNSCC) and is a clinically validated…”
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A tyrosine kinase inhibitor-induced interferon response positively associates with clinical response in EGFR-mutant lung cancer by Gurule, Natalia J., McCoach, Caroline E., Hinz, Trista K., Merrick, Daniel T., Van Bokhoven, Adriaan, Kim, Jihye, Patil, Tejas, Calhoun, Jacob, Nemenoff, Raphael A., Tan, Aik Choon, Doebele, Robert C., Heasley, Lynn E.

“…Tyrosine kinase inhibitors (TKIs) targeting EGFR-mutant lung cancers promote a range of tumor regression responses to yield variable residual disease, a likely…”
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IMMU-20. EVALUATION OF CAR T CELLS IN EPENDYMOMA by Nellan, Anandani, Donson, Andrew, Calhoun, Jacob, Griesinger, Andrea, Fry, Terry, Foreman, Nicholas

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EPEN-26. Chemokine receptor blockade reverses CCL2 mediated immunosuppression and restores CAR-T cell function in posterior fossa ependymoma by Cole, Allison P, Donson, Andrew M, Pierce, Angela M, Grimaldo, Enrique, Calhoun, Jacob D, Griesinger, Andrea M, Sublett, Caroline, Kaplan, Rosandra N, Fry, Terry J, Foreman, Nicholas K, Nellan, Anandani

“…Trastuzumab-based HER2 CAR-T constructs have demonstrated preclinical efficacy in medulloblastoma and are being evaluated for use in children and young adults…”
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Functional RNAi Screens Define Distinct Protein Kinase Vulnerabilities in EGFR-Dependent HNSCC Cell Lines by Hinz, Trista K, Kleczko, Emily K, Singleton, Katherine R, Calhoun, Jacob, Marek, Lindsay A, Kim, Jihye, Tan, Aik Choon, Heasley, Lynn E

“…The inhibitory epidermal growth factor receptor (EGFR) antibody, cetuximab, is an approved therapy for head and neck squamous cell carcinoma (HNSCC). Despite…”
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Experimental Results from the 1.2 ma, 2.2 m Diameter Linear Transformer Driver at Sandia National Labs by Douglass, J. D., Hutsel, B. T., Leckbee, J. J., Stoltzfus, B. S., Wisher, M. L., Savage, M. E., Stygar, W. A., Breden, E. W., Calhoun, J. D., Cuneo, M. E., Jaramillo, D. M., Johns, O. M., Jones, M. C., Lucero, D. J., Moore, J. K., Sceiford, M. E., Kiefer, M. L., Mulville, T. D., Sullivan, M. A., Hohlfelder, R. J.

“…Herein we describe the design, simulation and performance of a 118-GW linear transformer driver (LTD) cavity at Sandia National Laboratories. The cavity…”
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Disarming Reconstruction by Calhoun, J Jacob

“…LOUISIANA PLANTERS EMBRACE U.S. MILITARY INTERVENTION TO CORRAL SWEEPING SOCIAL CHANGES IN THEIR PARISH THE RECONSTRUCTION ACTS of 1867 entirely upended…”
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