Search Results - "Calero, A."
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Bioactivity and antibacterial properties of calcium- and silver-doped coatings on 3D printed titanium scaffolds
Published in Surface & coatings technology (15-09-2021)“…One of the major problems faced by metallic implants is the high probability of bacterial infections, with significant consequences for the patient. In this…”
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Splicing reprogramming of TRAIL/DISC-components sensitizes lung cancer cells to TRAIL-mediated apoptosis
Published in Cell death & disease (17-03-2021)“…Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) selective killing of cancer cells underlines its anticancer potential. However, poor…”
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Home-Based Trimodal Prehabilitation in Patients with Peritoneal Carcinomatosis Undergoing Cytoreductive Surgery: Effect on Functional Walking Capacity and Skeletal Muscle Mass
Published in Annals of surgical oncology (01-10-2024)“…Background Patients with peritoneal carcinomatosis often suffer from loss of skeletal muscle mass and require extensive surgery. Multimodal prehabilitation may…”
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Type of TP53 mutation influences oncogenic potential and spectrum of associated K‐ras mutations in lung‐specific transgenic mice
Published in International journal of cancer (01-11-2019)“…TP53 and K‐ras mutations are two of the major genetic alterations in human nonsmall cell lung cancers. The association between these two genes during lung…”
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Multi-Institutional Phase II Study of Selumetinib in Patients With Metastatic Biliary Cancers
Published in Journal of clinical oncology (10-06-2011)“…Biliary cancers (BCs) carry a poor prognosis, but targeting the RAS/RAF/mitogen-activated protein kinase kinase (MEK)/extracellular signal-related kinase (ERK)…”
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Randomized Phase II Trial of Erlotinib Alone or With Carboplatin and Paclitaxel in Patients Who Were Never or Light Former Smokers With Advanced Lung Adenocarcinoma: CALGB 30406 Trial
Published in Journal of clinical oncology (10-06-2012)“…Erlotinib is clinically effective in patients with non-small-cell lung cancer (NSCLC) who have adenocarcinoma, are never or limited former smokers, or have…”
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Randomized Phase 2 Trial of the Oncolytic Virus Pelareorep (Reolysin) in Upfront Treatment of Metastatic Pancreatic Adenocarcinoma
Published in Molecular therapy (01-06-2016)“…Pelareorep causes oncolysis in tumor cells with activated Ras. We hypothesized that pelareorep would have efficacy and immunomodulatory activity in metastatic…”
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A 2-center review of histopathology of variants of upper urinary tract urothelial carcinoma and their impact on clinical outcomes
Published in Urologic oncology (01-10-2024)“…•After pathological review variant histology is present in a third of UTUC.•Variant histology in UTUC as a high rate of concomitant CIS (71%).•Presence of…”
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Phase II Clinical Trial of Sorafenib in Metastatic Medullary Thyroid Cancer
Published in Journal of clinical oncology (10-05-2010)“…Mutations in the RET proto-oncogene and vascular endothelial growth factor receptor (VEGFR) activity are critical in the pathogenesis of medullary thyroid…”
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Oncolytic reovirus in combination with chemotherapy in metastatic or recurrent non–small cell lung cancer patients with KRAS‐activated tumors
Published in Cancer (15-03-2016)“…BACKGROUND The type 3 Dearing reovirus (Reolysin) is a naturally occurring virus that preferentially infects and causes oncolysis in tumor cells with a…”
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EML4‐ALK Rearrangement and Its Therapeutic Implications in Inflammatory Myofibroblastic Tumors
Published in The oncologist (Dayton, Ohio) (01-10-2018)“…With the advent of precision medicine, medical oncology is undergoing a transcendental change. These molecular studies have allowed us to learn about potential…”
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Myofascial Pain Syndrome: A Nociceptive Condition Comorbid with Neuropathic or Nociplastic Pain
Published in Life (Basel, Switzerland) (01-03-2023)“…Myofascial pain syndrome is featured by the presence of myofascial trigger points (TrPs). Whether TrPs are primary or secondary phenomena or if they relate to…”
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Probiotics to prevent necrotising enterocolitis and nosocomial infection in very low birth weight preterm infants
Published in British journal of nutrition (14-04-2017)“…The aim of the study was to determine whether routine probiotic supplementation (RPS) with Lactobacillus rhamnosus GG (LGG) or Lactobacillus acidophilus…”
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Irinotecan: mechanisms of tumor resistance and novel strategies for modulating its activity
Published in Annals of oncology (01-12-2002)“…Camptothecins are broad-spectrum anticancer drugs that specifically target DNA topoisomerase I (Topo I). The formation of a cleavable drug–Topo I–DNA complex…”
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The oncogenic potential of a mutant TP53 gene explored in two spontaneous lung cancer mice models
Published in BMC cancer (08-08-2020)“…Lung cancer is the number one cancer killer worldwide. A major drawback in the lung cancer treatment field is the lack of realistic mouse models that replicate…”
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Race and Ethnicity in Cancer Therapy: What Have We Learned?
Published in Clinical pharmacology and therapeutics (01-04-2014)“…Racial and ethnic disparities in the pathogenesis of common malignancies and outcomes from treatment remain a major health concern. Factors attributed to these…”
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Phase I study of 5-aza-2′-deoxycytidine in combination with valproic acid in non-small-cell lung cancer
Published in Cancer chemotherapy and pharmacology (2013)“…Purpose Non-small-cell lung cancer (NSCLC) accounts for the majority of lung cancer and is the most common cause of cancer death in industrialized countries…”
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MiRNA-200C expression in Fanconi anemia pathway functionally deficient lung cancers
Published in Scientific reports (24-02-2021)“…The Fanconi Anemia (FA) pathway is essential for human cells to maintain genomic integrity following DNA damage. This pathway is involved in repairing damaged…”
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Optimized Design and Implementation of Digital Lock-In for Planetary Exploration Sensors
Published in IEEE sensors journal (01-12-2022)“…Exploring life conditions on the near-Earth planets and satellites before carrying out human missions is an important task for Space Agencies. For that…”
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