Search Results - "Caldwell, M. A."

Clusterin secreted by astrocytes enhances neuronal differentiation from human neural precursor cells by Cordero-Llana, O, Scott, S A, Maslen, S L, Anderson, J M, Boyle, J, Chowhdury, R-R, Tyers, P, Barker, R A, Kelly, C M, Rosser, A E, Stephens, E, Chandran, S, Caldwell, M A

“…Neuronal differentiation from expanded human ventral mesencephalic neural precursor cells (NPCs) is very limited. Astrocytes are known to secrete neurotrophic…”
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Human Neural Precursor Cells Express Low Levels of Telomerase in Vitro and Show Diminishing Cell Proliferation with Extensive Axonal Outgrowth following Transplantation by Ostenfeld, Thor, Caldwell, Maeve A., Prowse, Karen R., Linskens, Maarten H., Jauniaux, Eric, Svendsen, Clive N.

“…Worldwideattention is presently focused on proliferating populations of neural precursor cells as an in vitro source of tissue for neural transplantation and…”
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A new method for the rapid and long term growth of human neural precursor cells by Svendsen, Clive N, ter Borg, Melanie G, Armstrong, Richard J.E, Rosser, Anne E, Chandran, S, Ostenfeld, Thor, Caldwell, Maeve A

“…A reliable source of human neural tissue would be of immense practical value to both neuroscientists and clinical neural transplantation trials. In this study,…”
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Astrocytes promote neurogenesis from oligodendrocyte precursor cells by Gaughwin, P. M., Caldwell, M. A., Anderson, J. M., Schwiening, C. J., Fawcett, J. W., Compston, D. A. S., Chandran, S.

“…The oligodendrocyte precursor cell (OPC) has until recently been regarded as a lineage‐restricted precursor cell. Considerable interest has been generated by…”
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Long-Term Survival of Human Central Nervous System Progenitor Cells Transplanted into a Rat Model of Parkinson's Disease by Svendsen, Clive N., Caldwell, Maeve A., Shen, Jinkun, ter Borg, Melanie G., Rosser, Anne E., Tyers, Pam, Karmiol, Soverin, Dunnett, Stephen B.

“…Progenitor cells were isolated from the developing human central nervous system (CNS), induced to divide using a combination of epidermal growth factor and…”
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Crystallization times of Ge–Te phase change materials as a function of composition by Raoux, S., Cheng, H.-Y., Caldwell, M. A., Wong, H.-S. P.

“…The crystallization times of Ge–Te phase change materials with variable Ge concentrations (29.5–72.4 at. %) were studied. A very strong dependence of the…”
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Twist-1 regulates the miR-199a/214 cluster during development by Lee, Youn-Bok, Bantounas, Ioannis, Lee, Do-Young, Phylactou, Leonidas, Caldwell, Maeve A, Uney, James B

“…MicroRNAs are known to regulate developmental processes but their mechanism of regulation remains largely uncharacterized. We show the transcription factor…”
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Signalling of DNA damage and cytokines across cell barriers exposed to nanoparticles depends on barrier thickness by Sood, A., Salih, S., Roh, D., Lacharme-Lora, L., Parry, M., Hardiman, B., Keehan, R., Grummer, R., Winterhager, E., Gokhale, P. J., Andrews, P. W., Abbott, C., Forbes, K., Westwood, M., Aplin, J. D., Ingham, E., Papageorgiou, I., Berry, M., Liu, J., Dick, A. D., Garland, R. J., Williams, N., Singh, R., Simon, A. K., Lewis, M., Ham, J., Roger, L., Baird, D. M., Crompton, L. A., Caldwell, M. A., Swalwell, H., Birch-Machin, M., Lopez-Castejon, G., Randall, A., Lin, H., Suleiman, M-S., Evans, W. H., Newson, R., Case, C. P.

“…The use of nanoparticles in medicine is ever increasing, and it is important to understand their targeted and non-targeted effects. We have previously shown…”
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Improving the survival of human CNS precursor-derived neurons after transplantation by Le Belle, J.E., Caldwell, M.A., Svendsen, C.N.

“…We have examined the effects of predifferentiation and energy substrate deprivation on long‐term expanded human neural precursor cells (HNPCs). The…”
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Heparin, but Not Other Proteoglycans Potentiates the Mitogenic Effects of FGF-2 on Mesencephalic Precursor Cells by Caldwell, Maeve A., Svendsen, Clive N.

“…There is increasing evidence that the proteoglycan heparin plays a critical role in the regulation of the activity of FGF-2 by either interacting with its…”
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Cross-regulation of Connexin43 and β-catenin influences differentiation of human neural progenitor cells by Rinaldi, F, Hartfield, E M, Crompton, L A, Badger, J L, Glover, C P, Kelly, C M, Rosser, A E, Uney, J B, Caldwell, M A

“…Connexin43 (Cx43) is the most widely and abundantly expressed gap junction (GJ) protein and it is strongly associated with the regulation of cell cycle…”
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Stem cells and neurological disease by Barker, R A, Jain, M, Armstrong, R J E, Caldwell, M A

“…Table 1 Essential properties of stem cells for use in clinical transplantation Disease Principle function required of stem cells Cell replacement Parkinson's…”
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Neural stem cells in the developing central nervous system: implications for cell therapy through transplantation by Svendsen, C N, Caldwell, M A

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Growth factors regulate the survival and fate of cells derived from human neurospheres by Caldwell, Maeve A, He, Xiaoling, Wilkie, Neil, Pollack, Scott, Marshall, George, Wafford, Keith A, Svendsen, Clive N

“…Cells isolated from the embryonic, neonatal, and adult rodent central nervous system divide in response to epidermal growth factor (EGF) and fibroblast growth…”
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Comparison of standard and derived 12-lead electrocardiograms for diagnosis of coronary angioplasty-induced myocardial ischemia by Drew, Barbara J., Adams, Mary G., Pelter, Michele M., Wung, Shu-Fen, Caldwell, Mary A.

“…To determine whether a derived 12-lead electrocardiogram (ECG) would demonstrate typical ST-segment changes of ischemia during percutaneous transluminal…”
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Mouse epidermal growth factor-responsive neural precursor cells increase the survival and functional capacity of embryonic rat dopamine neurons in vitro by Ostenfeld, Thor, Horn, Per, Aardal, Celine, Ørpen, Ingvild, Caldwell, Maeve A, Svendsen, Clive N

“…WE have grown expanded populations of epidermal growth factor (EGF)-responsive mouse striatal precursor cells and subsequently co-cultured these with primary…”
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Prehospital delay time in acute myocardial infarction: An exploratory study on relation to hospital outcomes and cost by Caldwell, Mary A., Sivarajan Froelicher, Erika, Drew, Barbara J.

“…Background Short prehospital delay is associated with improved outcomes in myocardial infarction, but the impact on cost has not been tested. Shortening delay…”
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The dopamine agonists lisuride and piribedil protect against behavioural and histological changes following 4-vessel occlusion in the rat by Caldwell, M A, Reymann, J M, Bentue-Ferrer, D, Allain, H, Leonard, B E

“…The 4-vessel occlusion model of ischaemia in the rat was used to assess the effects of two dopaminergic agonists, lisuride and piribedil, on some behavioural…”
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Chest pain is an unreliable measure of ischemia in men and women during PTCA by Caldwell, Mary A., Pelter, Michele M., Drew, Barbara J.

“…To investigate the differences between men and women in ischemia-induced pain, the amount of St-segment deviation (the “St deviation score”), and the relation…”
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Direct demonstration that increased phosphorylation of 3-hydroxy-3-methylglutaryl-CoA reductase does not increase its rate of degradation in isolated rat hepatocytes by ZAMMIT, V. A, CALDWELL, A. M

“…Increased phosphorylation of 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) reductase has been suggested to target the protein towards an increased rate of…”
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