Search Results - "Caldwell, L Elizabeth"

Suppression of p53 Function in Normal Human Mammary Epithelial Cells Increases Sensitivity to Extracellular Matrix-Induced Apoptosis by Seewaldt, Victoria L., Mrózek, Krzysztof, Sigle, Randy, Dietze, Eric C., Heine, Kevin, Hockenbery, David M., Hobbs, Katherine B., Caldwell, L. Elizabeth

“…Little is known about the fate of normal human mammary epithelial cells (HMECs) that lose p53 function in the context of extracellular matrix (ECM)-derived…”
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Retinoids and retinoic acid receptors regulate growth arrest and apoptosis in human mammary epithelial cells and modulate expression of CBP/p300 by Dietze, Eric C., Caldwell, L. Elizabeth, Marcom, Kelly, Collins, Steven J., Yee, Lisa, Swisshelm, Karen, Hobbs, Katherine B., Bean, Gregory R., Seewaldt, Victoria L.

“…Retinoids and retinoic acid receptors (RARs) are important mediators of normal epithelial cell homeostasis. To assess the role of retinoids and RARs in…”
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Tamoxifen but Not 4-Hydroxytamoxifen Initiates Apoptosis in p53(−) Normal Human Mammary Epithelial Cells by Inducing Mitochondrial Depolarization by Dietze, Eric C., Caldwell, L. Elizabeth, Grupin, Svetlana L., Mancini, Mariangela, Seewaldt, Victoria L.

“…Despite the widespread clinical use of tamoxifen as a breast cancer prevention agent, the molecular mechanism of tamoxifen chemoprevention is poorly…”
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CREB-binding protein regulates apoptosis and growth of HMECs grown in reconstituted ECM via laminin-5 by Dietze, Eric C, Bowie, Michelle L, Mrózek, Krzysztof, Caldwell, L Elizabeth, Neal, Cassandra, Marjoram, Robin J, Troch, Michelle M, Bean, Gregory R, Yokoyama, Kazunari K, Ibarra, Catherine A, Seewaldt, Victoria L

“…Interactions between normal mammary epithelial cells and extracellular matrix (ECM) are important for mammary gland homeostasis. Loss of interactions between…”
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Dysregulated expression of cyclin D1 in normal human mammary epithelial cells inhibits all-trans-retinoic acid-mediated G0/G1-phase arrest and differentiation in vitro by Seewaldt, V L, Kim, J H, Parker, M B, Dietze, E C, Srinivasan, K V, Caldwell, L E

“…Overexpression of cyclin D1 protein is observed in the majority of breast cancers, suggesting that dysregulated expression of cyclin D1 might be a critical…”
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Human papillomavirus type 16 E6 inactivation of p53 in normal human mammary epithelial cells promotes tamoxifen-mediated apoptosis by SEEWALDT, Victoria L, MROZEK, Krzysztof, DIETZE, Eric C, PARKER, Molly, CALDWELL, L. Elizabeth

“…Aberrant p53 expression is frequently observed in mammary epithelial cells obtained from women at high risk for developing breast cancer and is a predictor for…”
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Inhibition of retinoic acid receptor function in normal human mammary epithelial cells results in increased cellular proliferation and inhibits the formation of a polarized epithelium in vitro by Seewaldt, V L, Caldwell, L E, Johnson, B S, Swisshelm, K, Collins, S J, Tsai, S

“…The expression of retinoic acid receptor-beta (RAR beta) mRNA is absent or down-regulated in a majority of breast cancers, suggesting that loss of retinoic…”
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