Search Results - "Caldwell, Kevin K."

Prenatal alcohol exposure alters mRNA expression for stress peptides, glucocorticoid receptor function and immune factors in acutely stressed neonatal brain by Ruffaner-Hanson, Chaselyn D, Fernandez-Oropeza, Annette K, Sun, Melody S, Caldwell, Kevin K, Allan, Andrea M, Savage, Daniel D, Valenzuela, C Fernando, Noor, Shahani, Milligan, Erin D

“…The amygdala, hippocampus and hypothalamus are critical stress regulatory areas that undergo functional maturation for stress responding initially established…”
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Prenatal alcohol exposure modifies glucocorticoid receptor subcellular distribution in the medial prefrontal cortex and impairs frontal cortex-dependent learning by Allan, Andrea M, Goggin, Samantha L, Caldwell, Kevin K

“…Prenatal alcohol exposure (PAE) has been shown to impair learning, memory and executive functioning in children. Perseveration, or the failure to respond…”
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A novel method for the normalization of ChIP-qPCR data by Solomon, Elizabeth R, Caldwell, Kevin K, Allan, Andrea M

“…ChIP-qPCR permits the study of protein and chromatin interactions. The general technique can apply to the study of the interactions of protein with RNA, and…”
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Prenatal alcohol exposure results in brain region- and sex-specific changes in circHomer1 expression in adult mouse brain by Papageorgiou, Grigorios, Amoah, Stephen K, Pierotti, Caroline, Otero, Madison, Eckel, Sophie, Coffey, Kacie, Allan, Andrea M, Caldwell, Kevin K, Mellios, Nikolaos

“…Circular RNAs (circRNAs) are a novel category of covalently-closed non-coding RNAs mainly derived from the back-splicing of exons or introns of protein-coding…”
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Prenatal Alcohol Exposure Results in Sex-Specific Alterations in Circular RNA Expression in the Developing Mouse Brain by Paudel, Praveen, Pierotti, Caroline, Lozano, Evelyn, Amoah, Stephen K, Gardiner, Amy S, Caldwell, Kevin K, Allan, Andrea M, Mellios, Nikolaos

“…Fetal alcohol spectrum disorders (FASD) are heterogeneous disorders associated with alcohol exposure to the developing fetus that are characterized by a range…”
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Sex-Dependent Effects of the Histone Deacetylase Inhibitor, Sodium Valproate, on Reversal Learning After Developmental Arsenic Exposure by Tyler, Christina R Steadman, Smoake, Jane J W, Solomon, Elizabeth R, Villicana, Estrella, Caldwell, Kevin K, Allan, Andrea M

“…Several studies have demonstrated that exposure to arsenic in drinking water adversely affects brain development and cognitive function in adulthood. While the…”
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Hippocampal N-Methyl-d-Aspartate Receptor Subunit Expression Profiles in a Mouse Model of Prenatal Alcohol Exposure by Samudio-Ruiz, Sabrina L., Allan, Andrea M., Sheema, Sheema, Caldwell, Kevin K.

“…Background:  Although several reports have been published showing prenatal ethanol exposure is associated with alterations in N‐methyl‐d‐aspartate (NMDA)…”
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Dynamic regulation of corticostriatal glutamatergic synaptic expression during reversal learning in male mice by Chandrasekaran, Jayapriya, Caldwell, Kevin K., Brigman, Jonathan L.

“…•Glutamatergic NMDA and AMPA receptor subunit expression is dynamically expressed across touchscreen visual discrimination reversal learning in the cortical…”
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A Mouse Model of Prenatal Ethanol Exposure Using a Voluntary Drinking Paradigm by Allan, Andrea M., Chynoweth, Julie, Tyler, Lani A., Caldwell, Kevin K.

“…Background: The incidence of fetal alcohol spectrum disorders is estimated to be as high as 1 in 100 births. Efforts to better understand the basis of prenatal…”
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MicroRNA‐150‐5p is upregulated in the brain microvasculature during prenatal alcohol exposure and inhibits the angiogenic factor Vezf1 by Perales, Gabriela, Westenskow, Marissa, Gutierrez, Roxana, Caldwell, Kevin K., Allan, Andrea M., Gardiner, Amy S.

“…Background Fetal alcohol spectrum disorders (FASD) occur in children who were exposed to alcohol in utero and are manifested in a wide range of neurocognitive…”
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A Limited Access Mouse Model of Prenatal Alcohol Exposure that Produces Long-Lasting Deficits in Hippocampal-Dependent Learning and Memory by Brady, Megan L., Allan, Andrea M., Caldwell, Kevin K.

“…Background:  It has been estimated that approximately 12% of women consume alcohol at some time during their pregnancy, and as many as 5% of children born in…”
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Developmental arsenic exposure is associated with sex differences in the epigenetic regulation of stress genes in the adult mouse frontal cortex by Solomon, Elizabeth R., Caldwell, Kevin K., Allan, Andrea M.

“…Previously, we reported sex-dependent changes to global histone modifications and impairment of executive function in adult mice exposed to moderate levels of…”
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Identification of Myotubularin as the Lipid Phosphatase Catalytic Subunit Associated with the 3-Phosphatase Adapter Protein, 3-PAP by Nandurkar, Harshal H., Layton, Meredith, Laporte, Jocelyn, Selan, Carly, Corcoran, Lisa, Caldwell, Kevin K., Mochizuki, Yasuhiro, Majerus, Philip W., Mitchell, Christina A.

“…Myotubularin is a dual-specific phosphatase that dephosphorylates phosphatidylinositol 3-phosphate and phosphatidylinositol (3,5)-bisphosphate. Mutations in…”
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Aging Exacerbates Neuroinflammatory Outcomes Induced by Acute Ozone Exposure by Tyler, Christina R, Noor, Shahani, Young, Tamara L, Rivero, Valeria, Sanchez, Bethany, Lucas, Selita, Caldwell, Kevin K, Milligan, Erin D, Campen, Matthew J

“…Abstract The role of environmental stressors, particularly exposure to air pollution, in the development of neurodegenerative disease remains underappreciated…”
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The maternal-placental-fetal interface: Adaptations of the HPA axis and immune mediators following maternal stress and prenatal alcohol exposure by Ruffaner-Hanson, Chaselyn, Noor, Shahani, Sun, Melody S., Solomon, Elizabeth, Marquez, Lidia Enriquez, Rodriguez, Dominique E., Allan, Andrea M., Caldwell, Kevin K., Bakhireva, Ludmila N., Milligan, Erin D.

“…This review addresses underlying physiological, cellular, and molecular factors that alter the developing fetal brain stress circuits and responses of the…”
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Prenatal alcohol exposure alters p35, CDK5 and GSK3β in the medial frontal cortex and hippocampus of adolescent mice by Goggin, Samantha L, Caldwell, Kevin K, Cunningham, Lee Anna, Allan, Andrea M

“…Fetal alcohol spectrum disorders (FASDs) are the number one cause of preventable mental retardation. An estimated 2-5% of children are diagnosed as having a…”
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Moderate prenatal alcohol exposure reduces plasticity and alters NMDA receptor subunit composition in the dentate gyrus by Brady, Megan L, Diaz, Marvin R, Iuso, Anthony, Everett, Julie C, Valenzuela, C Fernando, Caldwell, Kevin K

“…Although it is well documented that heavy consumption of alcohol during pregnancy impairs brain development, it remains controversial whether moderate…”
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Arsenic exposure during embryonic development alters the expression of the long noncoding RNA growth arrest specific-5 (Gas5) in a sex-dependent manner by Caldwell, Kevin K., Hafez, Alexander, Solomon, Elizabeth, Cunningham, Matthew, Allan, Andrea M.

“…Our previous studies suggest that prenatal arsenic exposure (50ppb) modifies epigenetic control of the programming of the glucocorticoid receptor (GR)…”
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Prenatal Ethanol Exposure Reduces mGluR5 Receptor Number and Function in the Dentate Gyrus of Adult Offspring by Galindo, Rafael, Frausto, Shanti, Wolff, Christina, Caldwell, Kevin K., Perrone-Bizzozero, Nora I., Savage, Daniel D.

“…Background: Previous studies in our laboratory indicated that metabotropic glutamate receptor (mGluR)‐stimulated phosphoinositide hydrolysis is markedly…”
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Prenatal Alcohol Exposure Is Associated with Altered Subcellular Distribution of Glucocorticoid and Mineralocorticoid Receptors in the Adolescent Mouse Hippocampal Formation by Caldwell, Kevin K., Goggin, Samantha L., Tyler, Christina R., Allan, Andrea M.

“…Background Accumulating evidence indicates that several of the long‐term consequences of prenatal alcohol exposure (PAE) are the result of changes in the…”
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