Search Results - "Caldwell, J"
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Fatigue and its management in the workplace
Published in Neuroscience and biobehavioral reviews (01-01-2019)“…•Fatigue, or workplace sleepiness, is a consequence of modern industrial society.•Excessive sleepiness in the workplace and on highways is a serious safety…”
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Leadership development of individuals with developmental disabilities in the self-advocacy movement
Published in Journal of intellectual disability research (01-11-2010)“…Background Exploring the life stories of leaders in the self‐advocacy movement can expand our knowledge about leadership development of individuals with…”
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Chemical approaches to targeted protein degradation through modulation of the ubiquitin-proteasome pathway
Published in Biochemical journal (15-03-2017)“…Manipulation of the ubiquitin-proteasome system to achieve targeted degradation of proteins within cells using chemical tools and drugs has the potential to…”
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Allogeneic CAR Cell Therapy-More Than a Pipe Dream
Published in Frontiers in immunology (08-01-2021)“…Adoptive cellular immunotherapy using immune cells expressing chimeric antigen receptors (CARs) has shown promise, particularly for the treatment of…”
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Reconfigurable infrared hyperbolic metasurfaces using phase change materials
Published in Nature communications (22-10-2018)“…Metasurfaces control light propagation at the nanoscale for applications in both free-space and surface-confined geometries. However, dynamically changing the…”
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Binding of Released Bim to Mcl-1 is a Mechanism of Intrinsic Resistance to ABT-199 which can be Overcome by Combination with Daunorubicin or Cytarabine in AML Cells
Published in Clinical cancer research (01-09-2016)“…To investigate the molecular mechanism underlying intrinsic resistance to ABT-199. Western blots and real-time RT-PCR were used to determine levels of Mcl-1…”
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The Work Environment of the School Leader in Australia: The Case for Sustained Change in Role and Practice
Published in Education sciences (01-02-2024)“…The questions addressed in this essay are (1) how has the work environment of school leaders changed in the early years of the 21st century, (2) how have these…”
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Panobinostat enhances cytarabine and daunorubicin sensitivities in AML cells through suppressing the expression of BRCA1, CHK1, and Rad51
Published in PloS one (11-11-2013)“…Acute myeloid leukemia (AML) remains a challenging disease to treat and urgently requires new therapies to improve its treatment outcome. In this study, we…”
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An integrated approach for prioritizing pharmaceuticals found in the environment for risk assessment, monitoring and advanced research
Published in Chemosphere (Oxford) (01-11-2014)“…Numerous active pharmaceutical ingredients (APIs), approved prior to enactment of detailed environmental risk assessment (ERA) guidance in the EU in 2006, have…”
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Science‐based Targets for Antibiotics in Receiving Waters from Pharmaceutical Manufacturing Operations
Published in Integrated environmental assessment and management (01-05-2019)“…ABSTRACT In 2016, the United Nations declared the need for urgent action to combat the global threat of antimicrobial resistance (AMR). In support of this…”
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IL-1β in eosinophil-mediated small intestinal homeostasis and IgA production
Published in Mucosal immunology (01-07-2015)“…Eosinophils are multifunctional leukocytes that reside in the gastrointestinal (GI) lamina propria, where their basal function remains largely unexplored. In…”
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The Size Evolution of Galaxies since z~3: Combining SDSS, GEMS, and FIRES
Published in The Astrophysical journal (10-10-2006)Get full text
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Relationship between piperacillin concentrations, clinical factors and piperacillin/tazobactam-associated acute kidney injury
Published in Journal of antimicrobial chemotherapy (01-02-2023)“…Piperacillin/tazobactam, a commonly used antibiotic, is associated with acute kidney injury (AKI). The relationship between piperacillin concentrations and AKI…”
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Improving multi-tasking ability through action videogames
Published in Applied ergonomics (01-03-2013)“…The present study examined whether action videogames can improve multi-tasking in high workload environments. Two groups with no action videogame experience…”
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Ni-Catalyzed Enantioselective Intramolecular Mizoroki–Heck Reaction for the Synthesis of Phenanthridinone Derivatives
Published in Journal of organic chemistry (07-07-2023)“…A Ni-catalyzed enantioselective intramolecular Mizoroki–Heck reaction has been developed to transform symmetrical 1,4-cyclohexadienes with attached aryl…”
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Single-cell transcriptomic analysis of renal allograft rejection reveals insights into intragraft TCR clonality
Published in The Journal of clinical investigation (01-07-2023)“…Bulk analysis of renal allograft biopsies (rBx) identified RNA transcripts associated with acute cellular rejection (ACR); however, these lacked cellular…”
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Direct Electrical Stimulation in Electrocorticographic Brain-Computer Interfaces: Enabling Technologies for Input to Cortex
Published in Frontiers in neuroscience (07-08-2019)“…Electrocorticographic brain computer interfaces (ECoG-BCIs) offer tremendous opportunities for restoring function in individuals suffering from neurological…”
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Use of acute and chronic ecotoxicity data in environmental risk assessment of pharmaceuticals
Published in Environmental toxicology and chemistry (01-05-2016)“…For many older pharmaceuticals, chronic aquatic toxicity data are limited. To assess risk during development, scale‐up, and manufacturing processes, acute data…”
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Disease epidemic and a marine heat wave are associated with the continental-scale collapse of a pivotal predator ( Pycnopodia helianthoides )
Published in Science advances (01-01-2019)“…Multihost infectious disease outbreaks have endangered wildlife, causing extinction of frogs and endemic birds, and widespread declines of bats, corals, and…”
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