Search Results - "Caldwell, G A"
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Mitochondrial dysfunction, oxidative stress, and neurodegeneration elicited by a bacterial metabolite in a C. elegans Parkinson’s model
Published in Cell death & disease (01-01-2014)“…Genetic and idiopathic forms of Parkinson’s disease (PD) are characterized by loss of dopamine (DA) neurons and typically the formation of protein inclusions…”
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Differential neuroprotective effects of 14-3-3 proteins in models of Parkinson's disease
Published in Cell death & disease (01-01-2010)“…14-3-3 proteins are important negative regulators of cell death pathways. Recent studies have revealed alterations in 14-3-3s in Parkinson's disease (PD) and…”
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3
Suppression of polyglutamine-induced protein aggregation in Caenorhabditis elegans by torsin proteins
Published in Human molecular genetics (01-02-2003)“…Torsion dystonia is an autosomal dominant movement disorder characterized by involuntary, repetitive muscle contractions and twisted postures. The most severe…”
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Caenorhabditis elegans RAC1/ced-10 mutants as a new animal model to study very early stages of Parkinson’s disease
Published in Progress in neurobiology (01-03-2024)“…Patients with Parkinson’s disease (PD) display non-motor symptoms arising prior to the appearance of motor signs and before a clear diagnosis. Motor and…”
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A bacterial metabolite induces glutathione-tractable proteostatic damage, proteasomal disturbances, and PINK1-dependent autophagy in C. elegans
Published in Cell death & disease (01-10-2015)“…Gene-by-environment interactions are thought to underlie the majority of idiopathic cases of neurodegenerative disease. Recently, we reported that an…”
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Fungal lipopeptide mating pheromones: a model system for the study of protein prenylation
Published in Microbiological reviews (01-09-1995)“…In a variety of fungal species, mating between haploid cells is initiated by the action of peptide pheromones. The identification and characterization of…”
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7
Candida albicans gene encoding resistance to benomyl and methotrexate is a multidrug resistance gene
Published in Antimicrobial Agents and Chemotherapy (01-04-1994)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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8
Genetic Interactions Affecting Touch Sensitivity in Caenorhabditis elegans
Published in Proceedings of the National Academy of Sciences - PNAS (25-06-1996)“…At least 13 genes (mec-1, mec-2, mec-4-10, mec-12, mec-14, mec-15, and mec-18) are needed for the response to gentle touch by 6 touch receptor neurons in the…”
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Significance of C-terminal cysteine modifications to the biological activity of the Saccharomyces cerevisiae a-factor mating pheromone
Published in Molecular and Cellular Biology (01-07-1991)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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MEC-2 Is Recruited to the Putative Mechanosensory Complex in C. elegans Touch Receptor Neurons through Its Stomatin-like Domain
Published in Current biology (09-11-2004)“…Background: The response to gentle body touch in C. elegans requires a degenerin channel complex containing four proteins (MEC-2, MEC-4, MEC-6, and MEC-10)…”
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Consequences of altered isoprenylation targets on a-factor export and bioactivity
Published in Proceedings of the National Academy of Sciences - PNAS (15-02-1994)“…Cysteine-containing amino acid sequences (CAAX, CC, and CXC; C is cysteine, A is any aliphatic amino acid, and X is any amino acid) are targets for the…”
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12
Molecular determinants of bioactivity of the Saccharomyces cerevisiae lipopeptide mating pheromone
Published in The Journal of biological chemistry (05-08-1994)“…The a-factor of Saccharomyces cerevisiae (YIIKGVF-WDPAC(Farnesyl)-OCH3) is a peptide pheromone in which post-translational modification with a farnesyl…”
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13
Total synthesis of the lipopeptide a-mating factor of Saccharomyces cerevisiae
Published in Biochemical and biophysical research communications (14-07-1989)“…The a-mating factor of Saccharomyces cerevisiae was synthesized using both solution phase and solid phase strategies. Structure of the final peptide was…”
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14
Use of by-product gypsum to alleviate soil acidity
Published in Soil Science Society of America journal (01-07-1985)“…By‐product gypsum has been accumulating in large mounds in southern Louisiana for over 25 yr and little has been utilized. The objective of this study was to…”
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15
Response of determinate soybean cultivars to low pH soils
Published in Plant and soil (01-04-1991)“…The main purpose of this study was to identify soybean cultivars which maintained high yields on acid soil. A secondary purpose was to determine what nutrient…”
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16
Identification of a hyperactive mating pheromone of Saccharomyces cerevisiae
Published in Biochemical and biophysical research communications (30-12-1993)“…The yeast mating pheromone a-factor is a farnesylated peptide [YIIKGVFWDPAC(Farnesyl)-OCH3] involved in the signal transduction cascade which leads to sexual…”
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17
Evolutionarily conserved nuclear migration genes required for early embryonic development in Caenorhabditis elegans
Published in Development genes and evolution (01-09-2001)“…The nudF and nudC genes of the fungus Aspergillus nidulans encode proteins that are members of two evolutionarily conserved families. In A. nidulans these…”
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Synthesis and inhibitory activity on platelet aggregation of 13'-aza and other omega-chain modified BW245C analogues
Published in Archiv der Pharmazie (Weinheim) (1994)“…BW245C analogues which have 15'-keto, -oximino, -sulphinyl, -sulphonyl, -methyl, -1-adamantyl, 14'-hydroxy, 16'-hydroxy, 13'-14'-NH=CH, -NH-CH2, or -NH-CO…”
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Effects of natural and artificially induced reduction on soil solution phosphorus in rice soils
Published in Plant and soil (01-09-1987)“…The effect of natural and artificial reduction on P extractability from soils used for rice production and the relation of these values to response to…”
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Synthesis and platelet aggregation inhibiting activity of acid side-chain modified hydantoin prostaglandin analogues
Published in Archiv der Pharmazie (Weinheim) (1993)“…A series of hydantoin prostaglandin analogues, in which the hexamethylene moiety of the acid side chain was replaced by other spacing groups possessing either…”
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