Search Results - "Caldini, Riccardo"
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Low doses of 3-aminobenzamide, a poly(ADP-ribose) polymerase inhibitor, stimulate angiogenesis by regulating expression of urokinase type plasminogen activator and matrix metalloprotease 2
Published in Vascular cell (19-05-2011)“…Poly(ADP-Ribose) polymerase (PARP) activity has been demonstrated fundamental in many cellular processes, including DNA repair, cell proliferation and…”
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2
Poly(ADP-ribosyl)ation, a molecular switch of transcription, shows an attractive relationship with urokinase expression
Published in Thrombosis and haemostasis (01-02-2005)“…Poly(ADP-ribosyl)ation is a posttranslational modification of proteins that consists in the transfer of ADP-ribose units from NAD+ onto protein acceptors to…”
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3
Differentiating and Apoptotic Dose-Dependent Effects in (−)-α-Bisabolol-Treated Human Endothelial Cells
Published in Journal of natural products (Washington, D.C.) (23-04-2010)“…The effect on angiogenesis of (−)-α-bisabolol [(−)-6-methyl-2-(4-methyl-3-cyclohexen-1-yl)-5-hepten-2-ol] (1), a widely distributed plant sesquiterpene…”
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4
Inhibition of PARP activity by PJ-34 leads to growth impairment and cell death associated with aberrant mitotic pattern and nucleolar actin accumulation in M14 melanoma cell line
Published in Journal of cellular physiology (01-02-2010)“…The capability of PARP activity inhibitors to prevent DNA damage recovery suggested the use of these drugs as chemo‐ and radio‐sensitisers for cancer therapy…”
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5
Oxidative DNA damage repair and parp 1 and parp 2 expression in Epstein-Barr virus-immortalized B lymphocyte cells from young subjects, old subjects, and centenarians
Published in Rejuvenation research (01-06-2007)“…Oxidative DNA damage has been implicated in the aging process and in some of its features such as telomere shortening and replicative senescence…”
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6
FGF2-mediated upregulation of urokinase-type plasminogen activator expression requires a MAP-kinase dependent activation of poly(ADP-ribose) polymerase
Published in Journal of cellular physiology (01-01-2005)“…Poly(ADP‐ribosyl)ation is a post‐translational modification of protein occurring in the nucleus by poly(ADP‐ribose) polymerase enzyme activity. The main role…”
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7
Comparative levels of DNA breaks and sensitivity to oxidative stress in aged and senescent human fibroblasts: a distinctive pattern for centenarians
Published in Biogerontology (Dordrecht) (01-01-2003)“…Basal and H(2)O(2)-induced DNA breaks as well as DNA repair activity and efficacy of the antioxygenic system were determined in human dermal fibroblasts…”
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8
Urokinase-dependent angiogenesis in vitro and diacylglycerol production are blocked by antisense oligonucleotides against the urokinase receptor
Published in Laboratory investigation (01-09-1998)“…The plasminogen activator system is known to play a crucial role in the angiogenesis process by modulating the adhesive properties of endothelial cells to the…”
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9
Premature induction of aging in sublethally H2O2-treated young MRC5 fibroblasts correlates with increased glutathione peroxidase levels and resistance to DNA breakage
Published in Mechanisms of ageing and development (15-09-1998)“…Human MRC5 fibroblasts, at different passages in cultures, were used as an in vitro model to assess variations and/or induction of aging parameters under basal…”
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10
Heparin binding peptides co-purify with glycosaminoglycans from human plasma
Published in FEBS letters (10-12-1999)“…Glycosaminoglycans (GAGs) are complexed with plasma proteins and proteolysis of plasma reduced the protein–GAG ratio about 140-fold. After dialysis, analysis…”
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11
Production of second messengers following chemotactic and mitogenic urokinase-receptor interaction in human fibroblasts and mouse fibroblasts transfected with human urokinase receptor
Published in Experimental cell research (01-08-1994)“…We studied urokinase-type plasminogen activator (u-PA)-dependent chemotaxis and DNA synthesis in both human fibroblasts and LB6 mouse fibroblasts transfected…”
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12
Induction, Effects, and Quantification of Sublethal Oxidative Stress by Hydrogen Peroxide on Cultured Human Fibroblasts
Published in Experimental cell research (01-02-1995)“…Conditions to induce and parameters to evaluate sublethal oxidative stress of cultured human fibroblasts have been investigated in the attempt to identify…”
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13
Premature induction of aging in sublethally H 2O 2-treated young MRC5 fibroblasts correlates with increased glutathione peroxidase levels and resistance to DNA breakage
Published in Mechanisms of ageing and development (1998)“…Human MRC5 fibroblasts, at different passages in cultures, were used as an in vitro model to assess variations and/or induction of aging parameters under basal…”
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14
Interaction of Urokinase-Type Plasminogen Activator with Its Receptor Rapidly Induces Activation of Glucose Transporters
Published in Biochemistry (Easton) (18-03-1997)“…The interaction of urokinase-type plasminogen activator (u-PA) or of u-PA amino-terminal fragment (u-PA-ATF) with the cell surface receptor (u-PAR) was found…”
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15
Role of Specific Membrane Receptors in Urokinase-Dependent Migration of Human Keratinocytes
Published in Journal of investigative dermatology (01-03-1990)“…On the basis of both 125I-labeled plasminogen activator binding analysis and transmission electron microscopy studies of the interaction of a plasminogen…”
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16
Changes in pyridine and adenine nucleotide levels in Friend erythroleukaemia cells during growth and differentiation
Published in Journal of cellular physiology (01-04-1992)“…Pyridine and adenine nucleotide levels were measured in Friend erythroleukaemia cells (FELC) stimulated to growth and induced to differentiate by hexamethylene…”
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17
Plasminogen activators and tiaprofenic acid in inflammation. A preliminary study
Published in Drugs (New York, N.Y.) (1988)“…Treatment with tiaprofenic acid appreciably reduced the level of plasminogen activators in the medium of 3T3-Balb mouse fibroblasts, as revealed by both a…”
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18
Metabolic aspects of cell cycle regulation in normal and cancer cells
Published in Toxicologic pathology (1984)“…Several studies are reviewed dealing with the mechanisms which regulate the cell cycle progression in normal and cancer cells. Using Yoshida AH 130 ascites…”
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