Search Results - "Caldecourt, M A"

The mechanism of liposome accumulation in infarction by Palmer, T N, Caride, V J, Caldecourt, M A, Twickler, J, Abdullah, V

“…This paper explores the mechanism(s) whereby liposomes accumulate in chronically ischaemic myocardium and intestine. Plasma prepared from venous blood obtained…”
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The role of phosphoenolpyruvate carboxykinase in muscle alanine synthesis by Palmer, T N, Caldecourt, M A, Warner, J P, Sugden, M C

“…3-Mercaptopicolinic acid (3-MPA) is reportedly a specific inhibitor of phosphoenolpyruvate (PEP) carboxykinase and has hitherto been used accordingly to…”
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Is the direct effect of naloxone on liver cell metabolism an artifact? by Caldecourt, M A, Palmer, T N, Steare, S E, Sugden, M C, Watts, D I

“…Proprietary naloxone hydrochloride (Narcan) acts on isolated hepatocytes from 24-h starved rats to increase 14CO2 production from [1-14C]oleate and to reverse…”
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Adrenergic inhibition of branched-chain 2-oxo acid dehydrogenase in rat diaphragm muscle in vitro by Palmer, T N, Caldecourt, M A, Sugden, M C

“…In theory, the complete oxidation to CO2 of amino acids that are metabolized by conversion into tricarboxylic acid-cycle intermediates may proceed via their…”
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Amino acid oxidation and alanine production in rat hemidiaphragm in vitro. Effects of dichloroacetate by Palmer, T N, Caldecourt, M A, Sugden, M C

“…Dichloroacetate (an activator of pyruvate dehydrogenase) stimulates 14CO2 production from [U-14C]glucose, but not from [U-14C]glutamate, [U-14C]aspartate,…”
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Glycolytic origin of alanine formed in rat diaphragm muscle in vitro by Caldecourt, M A, Cox, D J, Sugden, M C, Palmer, T N

“…In quarter-diaphragms from 40 h-starved rats the rate of glycogen mobilization is sufficient to account for the rate of lactate+pyruvate+alanine production. It…”
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Modulation of branched-chain amino acid oxidation in rat hemidiaphragms in vitro by glucose and ketone bodies by Palmer, T N, Caldecourt, M A, Warner, J P, Sugden, M C

“…Branched-chain amino acid metabolism in hemidiaphragms from 40 h-starved rats is influenced by the provision of glucose as co-substrate. Glucose inhibits 14CO2…”
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Liposomal drug delivery in chronic ischaemia by Palmer, T N, Caldecourt, M A, Kingaby, R O

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Impaired muscle glucose metabolism in acute renal failure by Palmer, T N, Caldecourt, M A, Gossain, S, Mangat, S, Sugden, M C

“…Renal failure is associated with peripheral insulin resistance and consequent carbohydrate intolerance. This report investigates carbohydrate metabolism in…”
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Pyruvate kinase and alanine synthesis in skeletal muscle by Palmer, T N, Caldecourt, M A, Slavin, J P

“…L-Phenylalanine is an allosteric inhibitor of M1-type pyruvate kinase. Accordingly, the effects were studied of 20 mM phenylalanine on the metabolism of 5 mM…”
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Inhibition of lipogenesis by vasopressin and angiotensin II in glycogen-depleted hepatocytes by Palmer, T N, Caldecourt, M A, Watts, D I, Sugden, M C

“…Vasopressin and angiotensin II inhibited lipogenesis (measured with 3H2O) in hepatocytes from fed rats. Inhibition was also observed with hepatocytes from fed…”
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Alanine and inter-organ relationships in branched-chain amino and 2-oxo acid metabolism. Review by Palmer, T N, Caldecourt, M A, Snell, K, Sugden, M C

“…Branched-chain amino acid metabolism in skeletal muscle promotes the production of alanine, an important precursor in hepatic gluconeogenesis. There is…”
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Liposome accumulation in chronic ischaemia is dependent on tissue necrosis by Caldecourt, M A, Cole, A W, Kingaby, R O, Palmer, T N

“…Liposomes accumulate is ischaemic rat intestine 24 h after mesenteric occlusion. The accumulation of liposomal components is shown to depend on necrotic or…”
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