Search Results - "Caldarelli, Ilaria"

Genetic and Epigenetic Control of CDKN1C Expression: Importance in Cell Commitment and Differentiation, Tissue Homeostasis and Human Diseases by Stampone, Emanuela, Caldarelli, Ilaria, Zullo, Alberto, Bencivenga, Debora, Mancini, Francesco Paolo, Della Ragione, Fulvio, Borriello, Adriana

“…The gene encodes the p57 protein which has been identified as the third member of the CIP/Kip family, also including p27 and p21 . In analogy with these…”
Get full text

Resveratrol and cancer treatment: is hormesis a yet unsolved matter? by Borriello, Adriana, Bencivenga, Debora, Caldarelli, Ilaria, Tramontano, Annunziata, Borgia, Alessia, Pirozzi, Anna Virginia Adriana, Oliva, Adriana, Della Ragione, Fulvio

“…Plants produce many low molecular mass natural compounds endowed with biological activity. Among them, resveratrol (3,5,4'-trihydroxystilbene) has been…”
Get more information

The tyrosine kinase inhibitor dasatinib induces a marked adipogenic differentiation of human multipotent mesenchymal stromal cells by Borriello, Adriana, Caldarelli, Ilaria, Basile, Maria Assunta, Bencivenga, Debora, Tramontano, Annunziata, Perrotta, Silverio, Della Ragione, Fulvio, Oliva, Adriana

“…The introduction of specific BCR-ABL inhibitors in chronic myelogenous leukemia therapy has entirely mutated the prognosis of this hematologic cancer from…”
Get full text

Histone Deacetylase Inhibitors Increase p27Kip1 by Affecting Its Ubiquitin-Dependent Degradation through Skp2 Downregulation by Oliva, Adriana, Sinisi, Antonio, Spina, Annamaria, Della Ragione, Fulvio, Sapio, Luigi, Stampone, Emanuela, Speranza, Maria Carmela, Tramontano, Annunziata, Caldarelli, Ilaria, Bencivenga, Debora, Naviglio, Silvio, Borriello, Adriana, Negri, Aide

“…Histone deacetylase inhibitors (HDACIs) represent an intriguing class of pharmacologically active compounds. Currently, some HDACIs are FDA approved for cancer…”
Get full text

p57Kip2 and Cancer: Time for a Critical Appraisal by Borriello, Adriana, Caldarelli, Ilaria, Bencivenga, Debora, Criscuolo, Maria, Cucciolla, Valeria, Tramontano, Annunziata, Oliva, Adriana, Perrotta, Silverio, Della Ragione, Fulvio

“…Abstract p57Kip2 is a cyclin-dependent kinase inhibitor belonging to the Cip/Kip family, which also includes p21Cip1 and p27Kip1. So far, p57Kip2 is the…”
Get full text

p57 Kip2 is a downstream effector of BCR–ABL kinase inhibitors in chronic myelogenous leukemia cells by Borriello, Adriana, Caldarelli, Ilaria, Bencivenga, Debora, Cucciolla, Valeria, Oliva, Adriana, Usala, Emilio, Danise, Paolo, Ronzoni, Luisa, Perrotta, Silverio, Della Ragione, Fulvio

Get full text

Iron overload enhances human mesenchymal stromal cell growth and hampers matrix calcification by Borriello, Adriana, Caldarelli, Ilaria, Speranza, Maria Carmela, Scianguetta, Saverio, Tramontano, Annunziata, Bencivenga, Debora, Stampone, Emanuela, Negri, Aide, Nobili, Bruno, Locatelli, Franco, Perrotta, Silverio, Oliva, Adriana, Della Ragione, Fulvio

“…Iron overload syndromes include a wide range of diseases frequently associated with increased morbidity and mortality. Several organs are affected in patients…”
Get full text

Resveratrol: from basic studies to bedside by Borriello, Adriana, Bencivenga, Debora, Caldarelli, Ilaria, Tramontano, Annunziata, Borgia, Alessia, Zappia, Vincenzo, Della Ragione, Fulvio

“…Plants produce a remarkable amount of low molecular mass natural products endowed with a large array of pivotal biological activities. Among these molecules,…”
Get more information

p57(Kip2) and cancer: time for a critical appraisal by Borriello, Adriana, Caldarelli, Ilaria, Bencivenga, Debora, Criscuolo, Maria, Cucciolla, Valeria, Tramontano, Annunziata, Oliva, Adriana, Perrotta, Silverio, Della Ragione, Fulvio

“…p57(Kip2) is a cyclin-dependent kinase inhibitor belonging to the Cip/Kip family, which also includes p21(Cip1) and p27(Kip1). So far, p57(Kip2) is the…”
Get full text

p27Kip1and human cancers: A reappraisal of a still enigmatic protein by Bencivenga, Debora, Caldarelli, Ilaria, Stampone, Emanuela, Mancini, Francesco Paolo, Balestrieri, Maria Luisa, Fulvio Della Ragione, Borriello, Adriana

“…p27Kip1is a cell cycle regulator firstly identified as a cyclin-dependent kinase inhibitor. For a long time, its function has been associated to cell cycle…”
Get full text

p27 Kip1 and human cancers: A reappraisal of a still enigmatic protein by Bencivenga, Debora, Caldarelli, Ilaria, Stampone, Emanuela, Mancini, Francesco Paolo, Balestrieri, Maria Luisa, Della Ragione, Fulvio, Borriello, Adriana

“…p27 is a cell cycle regulator firstly identified as a cyclin-dependent kinase inhibitor. For a long time, its function has been associated to cell cycle…”
Get full text

p27Kip1 and human cancers: A reappraisal of a still enigmatic protein by Bencivenga, Debora, Caldarelli, Ilaria, Stampone, Emanuela, Mancini, Francesco Paolo, Balestrieri, Maria Luisa, Della Ragione, Fulvio, Borriello, Adriana

“…p27Kip1 is a cell cycle regulator firstly identified as a cyclin-dependent kinase inhibitor. For a long time, its function has been associated to cell cycle…”
Get full text

Tyrosine kinase inhibitors and mesenchymal stromal cells: effects on self-renewal, commitment and functions by Borriello, Adriana, Caldarelli, Ilaria, Bencivenga, Debora, Stampone, Emanuela, Perrotta, Silverio, Oliva, Adriana, Della Ragione, Fulvio

“…The hope of selectively targeting cancer cells by therapy and eradicating definitively malignancies is based on the identification of pathways or metabolisms…”
Get full text

Resveratrol mimics insulin activity in the adipogenic commitment of human bone marrow mesenchymal stromal cells by Caldarelli, Ilaria, Speranza, Maria Carmela, Bencivenga, Debora, Tramontano, Annunziata, Borgia, Alessia, Pirozzi, Anna Virginia Adriana, Perrotta, Silverio, Oliva, Adriana, Della Ragione, Fulvio, Borriello, Adriana

“…Bone marrow mesenchymal stromal cells (BM-MSCs) are multipotent cells capable of differentiating toward osteoblatic and adipocytic phenotypes. BM-MSCs play…”
Get full text

p27Kip1 serine 10 phosphorylation determines its metabolism and interaction with cyclin-dependent kinases by Bencivenga, Debora, Tramontano, Annunziata, Borgia, Alessia, Negri, Aide, Caldarelli, Ilaria, Oliva, Adriana, Perrotta, Silverio, Della Ragione, Fulvio, Borriello, Adriana

“…p27Kip1 is a critical modulator of cell proliferation by controlling assembly, localization and activity of cyclin-dependent kinase (CDK). p27Kip1 also plays…”
Get full text

Histone Deacetylase Inhibitors Increase p27(Kip1) by Affecting Its Ubiquitin-Dependent Degradation through Skp2 Downregulation by Borriello, Adriana, Naviglio, Silvio, Bencivenga, Debora, Caldarelli, Ilaria, Tramontano, Annunziata, Speranza, Maria Carmela, Stampone, Emanuela, Sapio, Luigi, Negri, Aide, Oliva, Adriana, Sinisi, Antonio Agostino, Spina, Annamaria, Della Ragione, Fulvio

“…Histone deacetylase inhibitors (HDACIs) represent an intriguing class of pharmacologically active compounds. Currently, some HDACIs are FDA approved for cancer…”
Get full text

Transferrin‐immune complex disease: A potentially overlooked gammopathy mediated by IgM and IgG by Forni, Gian Luca, Pinto, Valeria, Musso, Marco, Mori, Marco, Girelli, Domenico, Caldarelli, Ilaria, Borriello, Adriana, Ragione, Fulvio Della

“…The combination of marked hypersideremia, hypertransferrinemia, and monoclonal gammopathy of underdetermined significance (MGUS) should alert clinicians to the…”
Get full text

Cystatin B and its EPM1 mutants are polymeric and aggregate prone in vivo by Cipollini, Elena, Riccio, Massimo, Di Giaimo, Rossella, Dal Piaz, Fabrizio, Pulice, Giuseppe, Catania, Sandra, Caldarelli, Ilaria, Dembic, Maja, Santi, Spartaco, Melli, Marialuisa

“…Progressive myoclonus epilepsy type 1 (EPM1) is a neurodegenerative disease correlating with mutations of the cystatin B gene. Cystatin B is described as a…”
Get full text

Histone Deacetylase Inhibitors Increase p27 Kip1 by Affecting Its Ubiquitin‐Dependent Degradation through Skp2 Downregulation by Borriello, Adriana, Naviglio, Silvio, Bencivenga, Debora, Caldarelli, Ilaria, Tramontano, Annunziata, Speranza, Maria Carmela, Stampone, Emanuela, Sapio, Luigi, Negri, Aide, Oliva, Adriana, Sinisi, Antonio Agostino, Spina, Annamaria, Della Ragione, Fulvio

“…Histone deacetylase inhibitors (HDACIs) represent an intriguing class of pharmacologically active compounds. Currently, some HDACIs are FDA approved for cancer…”
Get full text

p57Kip2 is a downstream effector of BCR―ABL kinase inhibitors in chronic myelogenous leukemia cells by BORRIELLO, Adriana, CALDARELLI, Ilaria, BENCIVENGA, Debora, CUCCIOLLA, Valeria, OLIVA, Adriana, USALA, Emilio, DANISE, Paolo, RONZONI, Luisa, PERROTTA, Silverio, RAGIONE, Fulvio Della

“…Chronic myelogenous leukemia (CML) is characterized by the expression of BCR-ABL tyrosine kinase, which results in increased cell proliferation and inhibition…”
Get full text