Search Results - "Calcagno, Mario L"

CNS GNPDA2 Does Not Control Appetite, but Regulates Glucose Homeostasis by Gutierrez-Aguilar, Ruth, Grayson, Bernadette E, Kim, Dong-Hoon, Yalamanchili, Suma, Calcagno, Mario L, Woods, Stephen C, Seeley, Randy J

“…has been associated with human obesity and type-2 diabetes by using a GWAS approach. GNPDA2 is an enzyme involved in the hexosamine biosynthesis pathway, which…”
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The tertiary origin of the allosteric activation of E. coli glucosamine-6-phosphate deaminase studied by sol-gel nanoencapsulation of its T conformer by Zonszein, Sergio, Álvarez-Añorve, Laura I, Vázquez-Núñez, Roberto J, Calcagno, Mario L

“…The role of tertiary conformational changes associated to ligand binding was explored using the allosteric enzyme glucosamine-6-phosphate (GlcN6P) deaminase…”
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Allosteric Regulation of Glucosamine-6-Phosphate Deaminase (NagB) and Growth of Escherichia coli on Glucosamine by Alvarez-Añorve, Laura I, Bustos-Jaimes, Ismael, Calcagno, Mario L, Plumbridge, Jacqueline

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Allosteric kinetics of the isoform 1 of human glucosamine-6-phosphate deaminase by Álvarez-Añorve, Laura I., Alonzo, Diego A., Mora-Lugo, Rodrigo, Lara-González, Samuel, Bustos-Jaimes, Ismael, Plumbridge, Jacqueline, Calcagno, Mario L.

“…The human genome contains two genes encoding for two isoforms of the enzyme glucosamine-6-phosphate deaminase (GNPDA, EC 3.5.99.6). Isoform 1 has been purified…”
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Why Does Escherichia coli Grow More Slowly on Glucosamine than on N-Acetylglucosamine? Effects of Enzyme Levels and Allosteric Activation of GlcN6P Deaminase (NagB) on Growth Rates by ALVAREZ-ANORVE, Laura I, CALCAGNO, Mario L, PLUMBRIDGE, Jacqueline

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Substrate binding in the allosteric site mimics homotropic cooperativity in the SIS‐fold glucosamine‐6‐phosphate deaminases by Marcos‐Viquez, Jorge, Rodríguez‐Hernández, Annia, Álvarez‐Añorve, Laura I., Medina‐García, Andrea, Plumbridge, Jacqueline, Calcagno, Mario L., Rodríguez‐Romero, Adela, Bustos‐Jaimes, Ismael

“…Glucosamine‐6‐phosphate (GlcN6P) deaminases from Escherichia coli (EcNagBI) and Shewanella denitrificans (SdNagBII) are special examples of what constitute…”
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Allosteric Activation of Escherichia coli Glucosamine-6-Phosphate Deaminase (NagB) In Vivo Justified by Intracellular Amino Sugar Metabolite Concentrations by Álvarez-Añorve, Laura I, Gaugué, Isabelle, Link, Hannes, Marcos-Viquez, Jorge, Díaz-Jiménez, Dana M, Zonszein, Sergio, Bustos-Jaimes, Ismael, Schmitz-Afonso, Isabelle, Calcagno, Mario L, Plumbridge, Jacqueline

“…We have investigated the impact of growth on glucosamine (GlcN) and N-acetylglucosamine (GlcNAc) on cellular metabolism by quantifying glycolytic metabolites…”
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Kinetic studies of Gly28:Ser mutant form of Bacillus pumilus lipase: changes in k(cat) and thermal dependence by Bustos-Jaimes, Ismael, Mora-Lugo, Rodrigo, Calcagno, Mario L, Farrés, Amelia

“…Lipases are useful catalysts for a wide variety of industrial purposes. Herein we report the stability and thermal dependence of the activity of wild-type…”
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Kinetic studies of Gly28:Ser mutant form of Bacillus pumilus lipase: Changes in kcat and thermal dependence by Bustos-Jaimes, Ismael, Mora-Lugo, Rodrigo, Calcagno, Mario L., Farrés, Amelia

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Specialization of the paralogue LYS21 determines lysine biosynthesis under respiratory metabolism in Saccharomyces cerevisiae by Quezada, Hector, Aranda, Cristina, DeLuna, Alexander, Hernandez, Hugo, Calcagno, Mario L, Marin-Hernandez, Alvaro, Gonzalez, Alicia

“…1 Departamento de Genética Molecular, Instituto de Fisiología Celular, Universidad Nacional Autónoma de México, Apartado Postal 70-242, México DF 04510, México…”
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Structural Analysis of N-acetylglucosamine-6-phosphate Deacetylase Apoenzyme from Escherichia coli by Ferreira, Frederico M., Mendoza-Hernandez, Guillermo, Castañeda-Bueno, Maria, Aparicio, Ricardo, Fischer, Hannes, Calcagno, Mario L., Oliva, Glaucius

“…We report the crystal structure of the apoenzyme of N-acetylglucosamine-6-phosphate (GlcNAc6P) deacetylase from Escherichia coli ( EcNAGPase) and the…”
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On the functional role of Arg172 in substrate binding and allosteric transition in Escherichia coli glucosamine-6-phosphate deaminase by Lucumí-Moreno, Armando, Calcagno, Mario L.

“…Glucosamine-6-phosphate deaminase from Escherichia coli (EC 3.5.99.6) is an allosteric enzyme, activated by N-acetylglucosamine 6-phosphate, which converts…”
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Asymmetric allosteric activation of Escherichia coli glucosamine-6-phosphate deaminase produced by replacements of Tyr 121 by Altamirano, Myriam M, Plumbridge, Jacqueline A, Horjales, Eduardo, Calcagno, Mario L

“…Tyrosine 121, a residue located in a alpha-helical polypeptide segment of glucosamine 6-phosphate deaminase from Escherichia coli, has recently been proposed…”
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Evidence for Two Different Mechanisms Triggering the Change in Quaternary Structure of the Allosteric Enzyme, Glucosamine-6-Phosphate Deaminase by Bustos-Jaimes, Ismael, Ramírez-Costa, Montserrat, De Anda-Aguilar, Lorena, Hinojosa-Ocaña, Pilar, Calcagno, Mario L

“…The generation and propagation of conformational changes associated with ligand binding in the allosteric enzyme glucosamine-6-phosphate deaminase (GlcN6P…”
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On the Role of the Conformational Flexibility of the Active-site Lid on the Allosteric Kinetics of Glucosamine-6-phosphate Deaminase by Bustos-Jaimes, Ismael, Sosa-Peinado, Alejandro, Rudiño-Piñera, Enrique, Horjales, Eduardo, Calcagno, Mario L.

“…The active site of glucosamine-6-phosphate deaminase from Escherichia coli (GlcN6P deaminase, EC 3.5.99.6) has a complex lid formed by two antiparallel…”
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Inversion of the allosteric response of Escherichia coli glucosamine-6-P deaminase to N-acetylglucosamine 6-P, by single amino acid replacements by Cisneros, David A., Montero-Morán, Gabriela M., Lara-González, Samuel, Calcagno, Mario L.

“…Amino acid replacements in the active site of glucosamine-6-P deaminase from Escherichia coli (GlcN6P deaminase, EC 3.5.99.6) involving the residues D141 and…”
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The allosteric transition of glucosamine-6-phosphate deaminase: the structure of the T state at 2.3 Å resolution by Horjales, Eduardo, Altamirano, Myriam M, Calcagno, Mario L, Garratt, Richard C, Oliva, Glaucius

“…Background: The allosteric hexameric enzyme glucosamine-6-phosphate deaminase from Escherichia coli catalyses the regulatory step of N-acetylglucosamine…”
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On the Multiple Functional Roles of the Active Site Histidine in Catalysis and Allosteric Regulation of Escherichia coli Glucosamine 6-Phosphate Deaminase by Montero-Morán, Gabriela M, Lara-González, Samuel, Álvarez-Añorve, Laura I, Plumbridge, Jacqueline A, Calcagno, Mario L

“…The active site of glucosamine-6-phosphate deaminase (EC 3.5.99.6, formerly 5.3.1.10) from Escherichia coli was first characterized on the basis of the…”
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Structure and catalytic mechanism of glucosamine 6-phosphate deaminase from Escherichia coli at 2.1 å resolution by Oliva, Glaucius, Fontes, Marcos RM, Garratt, Richard C, Altamirano, Myriam M, Calcagno, Mario L, Horjales, Eduardo

“…Background: Glucosamine 6-phosphate deaminase from Escherichia coli is an allosteric hexameric enzyme which catalyzes the reversible conversion of D…”
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Tyr254 Hydroxyl Group Acts as a Two-Way Switch Mechanism in the Coupling of Heterotropic and Homotropic Effects in Escherichia coli Glucosamine-6-phosphate Deaminase by Montero-Morán, Gabriela M, Horjales, Eduardo, Calcagno, Mario L, Altamirano, Myriam M

“…The involvement of tyrosine residues in the allosteric function of the enzyme glucosamine 6-phosphate deaminase from Escherichia coli was first proposed on the…”
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