Search Results - "Calcagno, Elisa"

Synaptic and memory dysfunction induced by tau oligomers is rescued by up-regulation of the nitric oxide cascade by Acquarone, Erica, Argyrousi, Elentina K, van den Berg, Manon, Gulisano, Walter, Fà, Mauro, Staniszewski, Agnieszka, Calcagno, Elisa, Zuccarello, Elisa, D'Adamio, Luciano, Deng, Shi-Xian, Puzzo, Daniela, Arancio, Ottavio, Fiorito, Jole

“…Soluble aggregates of oligomeric forms of tau protein (oTau) have been associated with impairment of synaptic plasticity and memory in Alzheimer's disease…”
Get full text

Memory-enhancing effects of GEBR-32a, a new PDE4D inhibitor holding promise for the treatment of Alzheimer’s disease by Ricciarelli, Roberta, Brullo, Chiara, Prickaerts, Jos, Arancio, Ottavio, Villa, Carla, Rebosio, Claudia, Calcagno, Elisa, Balbi, Matilde, van Hagen, Britt T. J., Argyrousi, Elentina K., Zhang, Hong, Pronzato, Maria Adelaide, Bruno, Olga, Fedele, Ernesto

“…Memory loss characterizes several neurodegenerative disorders, including Alzheimer’s disease (AD). Inhibition of type 4 phosphodiesterase (PDE4) and elevation…”
Get full text

Correction: Synaptic and memory dysfunction induced by tau oligomers is rescued by up-regulation of the nitric oxide cascade by Acquarone, Erica, Argyrousi, Elentina K, van den Berg, Manon, Gulisano, Walter, Fà, Mauro, Staniszewski, Agnieszka, Calcagno, Elisa, Zuccarello, Elisa, D'Adamio, Luciano, Deng, Shi-Xian, Puzzo, Daniela, Arancio, Ottavio, Fiorito, Jole

Get full text

Development of novel phosphodiesterase 5 inhibitors for the therapy of Alzheimer’s disease by Zuccarello, Elisa, Acquarone, Erica, Calcagno, Elisa, Argyrousi, Elentina K., Deng, Shi-Xian, Landry, Donald W., Arancio, Ottavio, Fiorito, Jole

“…[Display omitted] Nitric oxide (NO) is a gaseous molecule that plays a multifactorial role in several cellular processes. In the central nervous system, the NO…”
Get full text

Amyloid-β Peptide Is Needed for cGMP-Induced Long-Term Potentiation and Memory by Palmeri, Agostino, Ricciarelli, Roberta, Gulisano, Walter, Rivera, Daniela, Rebosio, Claudia, Calcagno, Elisa, Tropea, Maria Rosaria, Conti, Silvia, Das, Utpal, Roy, Subhojit, Pronzato, Maria Adelaide, Arancio, Ottavio, Fedele, Ernesto, Puzzo, Daniela

“…High levels of amyloid-β peptide (Aβ) have been related to Alzheimer's disease pathogenesis. However, in the healthy brain, low physiologically relevant…”
Get full text

Tau is not necessary for amyloid-β-induced synaptic and memory impairments by Puzzo, Daniela, Argyrousi, Elentina K, Staniszewski, Agnieszka, Zhang, Hong, Calcagno, Elisa, Zuccarello, Elisa, Acquarone, Erica, Fa', Mauro, Li Puma, Domenica D, Grassi, Claudio, D'Adamio, Luciano, Kanaan, Nicholas M, Fraser, Paul E, Arancio, Ottavio

“…The amyloid hypothesis posits that the amyloid-beta (Aβ) protein precedes and requires microtubule-associated protein tau in a sort of trigger-bullet mechanism…”
Get full text

Histone Acetyltransferase (HAT) Activator, YF2, Modulates the p53:BCL6 Axis and Antigen Presentation in Diffuse Large B-Cell Lymphomas by Estrella, Brian, Liu, Yuxuan, Ricker, Edd C, Pazos, Manuel A, Fiorito, Jole, Zuccarello, Elisa, Calcagno, Elisa, Honig, Barry, Arancio, Ottavio, Amengual, Jennifer E.

“…A hallmark of DLBCL is epigenetic derangements characterized by monoallelic mutations in histone acetyltransferases (HATs); EP300 (p300) and CREBBP (CBP). The…”
Get full text

PDE5 inhibitors against synaptic and cognitive impairment in Alzheimer’s disease and related dementia by Arancio, Ottavio, Zuccarello, Elisa, Fiorito, Jole, Acquarone, Erica, Argyrousi, Elentina, Staniszewski, Agnieszka, Calcagno, Elisa, Puzzo, Daniela, Deng, Shi‐Xian, Landry, Donald

“…Background Gene transcription mechanisms leading to synaptic plasticity and memory formation, including phosphorylation of the transcription factor CREB, are…”
Get full text

Investigating the amyloid-beta enhancing effect of cGMP in neuro2a cells by Calcagno, Elisa, Caudano, Francesca, Passalacqua, Mario, Pronzato, Maria A., Fedele, Ernesto, Ricciarelli, Roberta

“…•Increased levels of cGMP boost the production of amyloid-beta peptides.•A mechanism for the amyloidogenic effect of cGMP is proposed.•The mechanism relies on…”
Get full text

Strategy for Overcoming Crebbp and EP300 Mutations in Lymphoma: Development of First-in-Class HAT Activators by Liu, Yuxuan, Fiorito, Jole, Gonzalez, Yulissa, Estrella, Brian, Calcagno, Elisa, Zuccarello, Elisa, Hwang, Howook, Honig, Barry, Deng, Shixian, Landry, Donald, O'Connor, Owen A., Arancio, Ottavio, Amengual, Jennifer E

“…Epigenetic dysregulation is a hallmark of germinal center derived B cell lymphomas. In particular, the monoallelic mutations in histone acetyltransferases…”
Get full text

Tau is not necessary for amyloid-β–induced synaptic and memory impairments by Puzzo, Daniela, Argyrousi, Elentina K, Staniszewski, Agnieszka, Zhang, Hong, Calcagno, Elisa, Zuccarello, Elisa, Acquarone, Erica, Fa, Mauro, Puma, Domenica D Li, Grassi, Claudio, D'Adamio, Luciano, Kanaan, Nicholas M, Fraser, Paul E, Arancio, Ottavio

“…The amyloid hypothesis posits that the amyloid-beta (Aß) protein precedes and requires microtubule-associated protein tau in a sort of trigger-bullet mechanism…”
Get full text

Tau is not necessary for amyloid-[beta]-induced synaptic and memory impairments by Puzzo, Daniela, Argyrousi, Elentina K, Staniszewski, Agnieszka, Zhang, Hong, Calcagno, Elisa, Zuccarello, Elisa, Acquarone, Erica, Fa', Mauro, Puma, Domenica D. Li, Grassi, Claudio, D'Adamio, Luciano, Kanaan, Nicholas M, Fraser, Paul E, Arancio, Ottavio

“…The amyloid hypothesis posits that the amyloid-beta (A[beta]) protein precedes and requires microtubule-associated protein tau in a sort of trigger-bullet…”
Get full text

Development of First-in-Class Histone Acetyltransferase (HAT) Activators for Precision Targeting of Epigenetic Derangements in Lymphoma by Liu, Yuxuan, Fiorito, Jole, Gonzalez, Yulissa, Zuccarello, Elisa, Calcagno, Elisa, Mazzeo, Adolfo, Abshiru, Nebiyu Ali, Camarillo, Jeannie, Kelleher, Neil L, Qiao, Changhong, Nandakumar, Renu, Serge, Cremers, Deng, Shixian, Landry, Donald, O'Connor, Owen A., Arancio, Ottavio, Amengual, Jennifer E

“…Monoalleleic inactivating mutations in histone acetyltransferase (HAT) enzymes promote lymphomagenesis in germinal center derived B-cell lymphomas, follicular…”
Get full text