Search Results - "Calcagnile, A."

The role of CSA in the response to oxidative DNA damage in human cells by D'ERRICO, M, PARLANTI, E, ORIOLI, D, FROSINA, G, ZAMBRUNO, G, DIZDAROGLU, M, STEFANINI, M, DOGLIOTTI, E, TESON, M, DEGAN, P, LEMMA, T, CALCAGNILE, A, IAVARONE, I, JARUGA, P, ROPOLO, M, PEDRINI, A. M

“…Cockayne syndrome (CS) is a rare genetic disease characterized by severe growth, mental retardation and pronounced cachexia. CS is most frequently due to…”
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Extended evaluation of the efficacy of a proactive forced oscillation technique-based auto-CPAP algorithm by Herkenrath, S. D., Treml, M., Anduleit, N., Richter, K., Pietzke-Calcagnile, A., Schwaibold, M., Schäfer, R., Alshut, R., Grimm, A., Hagmeyer, L., Randerath, W. J.

“…Purpose Previous studies revealed substantially varying therapy efficacy of automatic continuous positive airway pressure (APAP) devices in the treatment of…”
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Apoptosis and efficient repair of DNA damage protect human keratinocytes against UVB by D'Errico, M, Teson, M, Calcagnile, A, Proietti De Santis, L, Nikaido, O, Botta, E, Zambruno, G, Stefanini, M, Dogliotti, E

“…Cell Death and Differentiation (2003) 10, 754-756. doi:10.1038/sj.cdd.4401224…”
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p53 mutations and chromosome instability in basal cell carcinomas developed at an early or late age by D'ERRICO, M, CALCAGNILE, A. S, CORONA, R, FUCCI, M, ANNESSI, G, BALIVA, G, TOSTI, M. E, PASQUINI, P, DOGLIOTTI, E

“…Tumor DNA from 45 primary basal cell carcinoma (BCC) biopsies was screened for p53 gene mutations, chromosome 9 allele loss, and microsatellite instability…”
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Characterization of the ultraviolet B and X-ray response of primary cultured epidermal cells from patients with disseminated superficial actinic porokeratosis by D'Errico, M., Teson, M., Calcagnile, A., Corona, R., Didona, B., Meschini, R., Zambruno, G., Dogliotti, E.

“…Summary Background  Disseminated superficial actinic porokeratosis (DSAP) is the most common porokeratosis and is characterized by multiple keratotic lesions…”
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Misincorporation Rate and Type on the Leading and Lagging Strands of UV-Damaged DNA by Calcagnile, A., Basic-Zaninovic, T., Palombo, F., Dogliotti, E.

“…We have examined the fidelity of replication of the leading and lagging strands of UV-irradiated DNA by using an EBV-derived shuttle vector system which…”
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Genome-wide expression profile of sporadic gastric cancers with microsatellite instability by D’Errico, Mariarosaria, Rinaldis, Emanuele de, Blasi, Monica F, Viti, Valentina, Falchetti, Mario, Calcagnile, Angelo, Sera, Francesco, Saieva, Calogero, Ottini, Laura, Palli, Domenico, Palombo, Fabio, Giuliani, Alessandro, Dogliotti, Eugenia

“…Abstract Gastric cancers with mismatch repair (MMR) inactivation are characterised by microsatellite instability (MSI). In this study, the transcriptional…”
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N-methyl-N-nitrosourea-induced mutations in human cells. Effects of the transcriptional activity of the target gene by Palombo, F, Kohfeldt, E, Calcagnile, A, Nehls, P, Dogliotti, E

“…In this study we addressed the question as to whether the mutagenesis by methylating agents is affected by the transcriptional activity of the damaged gene. An…”
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Cell type and DNA damage specific response of human skin cells to environmental agents by D'Errico, Mariarosaria, Lemma, Tiziana, Calcagnile, Angelo, Proietti De Santis, Luca, Dogliotti, Eugenia

“…The epidermis has evolved to provide a barrier against the environment, which is essential for survival. This barrier is constituted and continuously…”
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Methoxyamine modification of abasic sites protects CHO cells from the cytotoxic and mutagenic effects of oxygen alkylation by Fortini, P, Rosa, S, Zijno, A, Calcagnile, A, Bignami, M, Dogliotti, E

“…The biological effects of the interaction of methoxyamine (MX) with apurinic/apyrimidinic (AP) sites produced in CHO cells by treatment with alkylating agents…”
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Molecular analysis of mutations induced by chemical carcinogens in mammalian cells. II. The use of recombinant DNA vectors by Basic-Zaninovic, T, Palombo, F, Calcagnile, A S, Dogliotti, E

“…One approach to molecular and mechanistic studies of mutagenesis in mammalian cells is to introduce a mutational target gene into the cells as part of a…”
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Quantitative relationship between ethylated DNA bases and gene mutation at two loci in CHO cells by Fortini, P, Calcagnile, A, Di Muccio, A, Bignami, M, Dogliotti, E

“…In a previous study we showed that the formation of O6-ethylguanine (O6-EtGua) in the DNA of CHO cells in culture correlated with mutations induced by…”
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Differential role of transcription-coupled repair in UVB-induced response of human fibroblasts and keratinocytes by D'Errico, Mariarosaria, Teson, Massimo, Calcagnile, Angelo, Nardo, Tiziana, De Luca, Naomi, Lazzari, Chiara, Soddu, Silvia, Zambruno, Giovanna, Stefanini, Miria, Dogliotti, Eugenia

“…Most solar radiation-induced skin cancers arise in keratinocytes. In the human epidermis, protection against cancer is thought to be mediated mainly by…”
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Induction kinetics of mutations at two genetic loci, DNA damage and repair in CHO cells after different exposure times to N-ethyl-N-nitrosourea by Dogliotti, E, Vitelli, A, Terlizzese, M, Di Muccio, A, Calcagnile, A, Saffiotti, U, Bignami, M

“…Ouabain resistance (ouar) and 6-thioguanine resistance (6-TGr) mutation frequencies were measured in Chinese hamster ovary cells after treatment with…”
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Molecular approaches to the study of chemical mutagenesis by Palombo, F, Calcagnile, A, Dogliotti, E

“…The use of shuttle vectors has been applied in recent years to develop a better understanding of the molecular mechanisms of mutagenesis in mammalian cells…”
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Cytotoxicity, mutations and SCEs induced by methylating agents are reduced in CHO cells expressing an active mammalian O6-methylguanine-DNA methyltransferase gene by Bignami, M, Terlizzese, M, Zijno, A, Calcagnile, A, Frosina, G, Abbondandolo, A, Dogliotti, E

“…Alkylation at the O6 position of guanine leading to miscoding during DNA replication has been shown to correlate with mutagenesis both in bacteria and…”
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Strand bias of ultraviolet light-induced mutations in a transcriptionally active gene in human cells by Basic-Zaninovic, T, Meschini, R, Calcagnile, A S, Palombo, F, D'Errico, M, Proietti-De Sanctis, L, Dogliotti, D, Proitti-De Sactis, L

“…Ultraviolet (UV)-induced repair and mutational spectra were analyzed in an inducible marker gene, the metallothionein-l/guamine-xanthine phosphoribosyl…”
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The origin of DNA single strand breaks induced by ethylating agents in mammalian cells by Vitelli, A, Di Muccio, A, Calcagnile, A, Zapponi, G A, Bignami, M, Dogliotti, E

“…Chinese hamster ovary (CHO) cells were treated with two ethylating agents, N-ethyl-N-nitrosourea (ENU) and diethylsulfate (DES), and the kinetics of DNA single…”
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Uv mutation signature in tumor suppressor genes involved in skin carcinogenesis in xeroderma pigmentosum patients by D'ERRICO, M, CALCAGNILE, A, DOGLIOTTI, E, CANZONA, F, DIDONA, B, POSTERARO, P, CAVALIERI, R, CORONA, R, VORECHOVSKY, I, NARDO, T, STEFANINI, M

“…Molecular analysis of p53 and patched (PTCH), two candidate tumor suppressor genes for non-melanocytic skin cancer, was performed in skin tumors from six…”
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Factors That Influence the DNA Repair Capacity of Normal and Skin Cancer-affected Individuals by D'ERRICO, M, CALCAGNILE, A, IAVARONE, I, SERA, F, BALIVA, G, CHINNI, L. M, CORONA, R, PASQUINI, P, DOGLIOTTI, E

“…DNA repair capacity (DRC) was studied in 49 patients affected by basal cell carcinoma (BCC) and 68 cancer-free controls belonging to a larger case-control…”
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