Search Results - "Calas, Andre"

Respiratory failure triggered by cholinesterase inhibitors may involve activation of a reflex sensory pathway by acetylcholine spillover by Nervo, Aurélie, Calas, André-Guilhem, Nachon, Florian, Krejci, Eric

“…[Display omitted] •Inhibition of cholinesterase by organophosphate poisoning strongly impacts respiration patterns.•Long pauses after inspiration are mainly…”
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Immunomodulatory influence of bone marrow-derived mesenchymal stem cells on neuroinflammation in astrocyte cultures by Schäfer, Sabrina, Calas, André-Guilhem, Vergouts, Maxime, Hermans, Emmanuel

“…Abstract The therapeutic benefits associated with mesenchymal stem cells (MSCs) largely result from their immunomodulatory and neurotrophic properties. In this…”
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Early ALS-type gait abnormalities in AMP-dependent protein kinase-deficient mice suggest a role for this metabolic sensor in early stages of the disease by Vergouts, Maxime, Marinangeli, Claudia, Ingelbrecht, Caroline, Genard, Geraldine, Schakman, Olivier, Sternotte, Anthony, Calas, André-Guilhem, Hermans, Emmanuel

“…Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by the selective loss of motoneurons. While the principal cause of the disease…”
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A New Class of Bi- and Trifunctional Sugar Oximes as Antidotes against Organophosphorus Poisoning by Da Silva, Ophélie, Probst, Nicolas, Landry, Christophe, Hanak, Anne-Sophie, Warnault, Pierre, Coisne, Caroline, Calas, André-Guilhem, Gosselet, Fabien, Courageux, Charlotte, Gastellier, Anne-Julie, Trancart, Marilène, Baati, Rachid, Dehouck, Marie-Pierre, Jean, Ludovic, Nachon, Florian, Renard, Pierre-Yves, Dias, José

“…Recent events demonstrated that organophosphorus nerve agents are a serious threat for civilian and military populations. The current therapy includes a…”
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No-observed-adverse-effect-level (NOAEL) assessment as an optimized dose of cholinesterase reactivators for the treatment of exposure to warfare nerve agents in mice by Trancart, Marilène, Hanak, Anne-Sophie, Dambrune, Chloé, Madi, Méliati, Voros, Camille, Baati, Rachid, Calas, André-Guilhem

“…Despite the international convention on the prohibition of chemical weapons ratified in 1997, the threat of conflicts and terrorist attacks involving such…”
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How does organophosphorus chemical warfare agent exposure affect respiratory physiology in mice? by Trancart, Marilène, Botta, Antoine, Le Coz, Christine, Guatto, Nathalie, Calas, André-Guilhem, Hanak, Anne-Sophie

“…In the absence of appropriate medical care, exposure to organophosphorus nerve agents, such as VX, can lead to respiratory failure, and potentially death by…”
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Excessive tubulin polyglutamylation causes neurodegeneration and perturbs neuronal transport by Magiera, Maria M, Bodakuntla, Satish, Žiak, Jakub, Lacomme, Sabrina, Marques Sousa, Patricia, Leboucher, Sophie, Hausrat, Torben J, Bosc, Christophe, Andrieux, Annie, Kneussel, Matthias, Landry, Marc, Calas, André, Balastik, Martin, Janke, Carsten

“…Posttranslational modifications of tubulin are emerging regulators of microtubule functions. We have shown earlier that upregulated polyglutamylation is linked…”
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Selenoprotein T is a novel OST subunit that regulates UPR signaling and hormone secretion by Hamieh, Abdallah, Cartier, Dorthe, Abid, Houssni, Calas, André, Burel, Carole, Bucharles, Christine, Jehan, Cedric, Grumolato, Luca, Landry, Marc, Lerouge, Patrice, Anouar, Youssef, Lihrmann, Isabelle

“…Selenoprotein T (SelT) is a recently characterized thioredoxin‐like protein whose expression is very high during development, but is confined to endocrine…”
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Bidirectional integrative regulation of Cav1.2 calcium channel by microRNA miR-103: role in pain by Favereaux, Alexandre, Thoumine, Olivier, Bouali-Benazzouz, Rabia, Roques, Virginie, Papon, Marie-Amélie, Salam, Sherine Abdel, Drutel, Guillaume, Léger, Claire, Calas, André, Nagy, Frédéric, Landry, Marc

“…Chronic pain states are characterized by long‐term sensitization of spinal cord neurons that relay nociceptive information to the brain. Among the mechanisms…”
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An Antidote Screening System for Organophosphorus Poisoning Using Zebrafish Larvae by Dubrana, Leslie E, Knoll-Gellida, Anja, Bourcier, Laure M, Mercé, Théo, Pedemay, Sandra, Nachon, Florian, Calas, André-Guilhem, Baati, Rachid, Soares, Magalie, Babin, Patrick J

“…Organophosphorus (OP) cholinesterase inhibitors, which include insecticides and chemical warfare nerve agents, are very potent neurotoxicants. Given that the…”
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An easy method for the determination of active concentrations of cholinesterase reactivators in blood samples: Application to the efficacy assessment of non quaternary reactivators compared to HI-6 and pralidoxime in VX-poisoned mice by Calas, André-Guilhem, Dias, José, Rousseau, Catherine, Arboléas, Mélanie, Touvrey-Loiodice, Mélanie, Mercey, Guillaume, Jean, Ludovic, Renard, Pierre-Yves, Nachon, Florian

“…Organophosphorus nerve agents, like VX, are highly toxic due to their strong inhibition potency against acetylcholinesterase (AChE). AChE inhibited by VX can…”
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Characterization of seizures induced by acute exposure to an organophosphate herbicide, glufosinate-ammonium by Calas, André-Guilhem, Perche, Olivier, Richard, Olivier, Perche, Astrid, Pâris, Arnaud, Lauga, Fabien, Herzine, Ameziane, Palomo, Jennifer, Ardourel, Marie-Yvonne, Menuet, Arnaud, Mortaud, Stéphane, Pichon, Jacques, Montécot-Dubourg, Céline

“…Glufosinate-ammonium (GLA), the active component of a widely used herbicide, induces convulsions in rodents and humans. In mouse, intraperitoneal treatment…”
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Noradrenergic regulation of galanin expression in the supraoptic nucleus in the rat hypothalamus. An ex vivo study by Melnikova, Victoria I., Raison, Danièle, Hardin-Pouzet, Hélène, Ugrumov, Mikhail V., Calas, Andre, Grange-Messent, Valerie

“…Galanin is coexpressed with vasopressin and oxytocin in magnocellular neurons of the rat neuroendocrine hypothalamus. Various physiological stimuli, such as…”
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Efficacy Assessment of an Uncharged Reactivator of NOP-Inhibited Acetylcholinesterase Based on Tetrahydroacridine Pyridine-Aldoxime Hybrid in Mouse Compared to Pralidoxime by Calas, André-Guilhem, Hanak, Anne-Sophie, Jaffré, Nina, Nervo, Aurélie, Dias, José, Rousseau, Catherine, Courageux, Charlotte, Brazzolotto, Xavier, Villa, Pascal, Obrecht, Adeline, Goossens, Jean-François, Landry, Christophe, Hachani, Johan, Gosselet, Fabien, Dehouck, Marie-Pierre, Yerri, Jagadeesh, Kliachyna, Maria, Baati, Rachid, Nachon, Florian

“…(1) Background: Human exposure to organophosphorus compounds employed as pesticides or as chemical warfare agents induces deleterious effects due to…”
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A secretagogin locus of the mammalian hypothalamus controls stress hormone release by Romanov, Roman A, Alpár, Alán, Zhang, Ming-Dong, Zeisel, Amit, Calas, André, Landry, Marc, Fuszard, Matthew, Shirran, Sally L, Schnell, Robert, Dobolyi, Árpád, Oláh, Márk, Spence, Lauren, Mulder, Jan, Martens, Henrik, Palkovits, Miklós, Uhlen, Mathias, Sitte, Harald H, Botting, Catherine H, Wagner, Ludwig, Linnarsson, Sten, Hökfelt, Tomas, Harkany, Tibor

“…A hierarchical hormonal cascade along the hypothalamic‐pituitary‐adrenal axis orchestrates bodily responses to stress. Although corticotropin‐releasing hormone…”
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The Suprachiasmatic Nucleus of the Dromedary Camel ( Camelus dromedarius ): Cytoarchitecture and Neurochemical Anatomy by El Allali, Khalid, Achaâban, Mohamed R, Piro, Mohammed, Ouassat, Mohammed, Challet, Etienne, Errami, Mohammed, Lakhdar-Ghazal, Nouria, Calas, André, Pévet, Paul

“…In mammals, biological rhythms are driven by a master circadian clock located in the suprachiasmatic nucleus (SCN) of the hypothalamus. Recently, we have…”
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Occurrence of Two Distinct Urotensin II-Related Peptides in Zebrafish Provides New Insight into the Evolutionary History of the Urotensin II Gene Family by Parmentier, Caroline, Hameury, Emilie, Dubessy, Christophe, Quan, Feng B, Habert, Damien, Calas, André, Vaudry, Hubert, Lihrmann, Isabelle, Tostivint, Hervé

“…The UII gene family possesses four distinct paralogs that arose during two rounds of tetraploidization: urotensin II, urotensin II-related peptide (URP) and…”
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Comparative Genomics Provides Evidence for Close Evolutionary Relationships between the Urotensin II and Somatostatin Gene Families by Tostivint, Hervé, Joly, Lucille, Lihrmann, Isabelle, Parmentier, Caroline, Lebon, Alexis, Morisson, Mireille, Calas, André, Ekker, Marc, Vaudry, Hubert

“…Although urotensin II (UII) and somatostatin 1 (SS1) exhibit some structural similarities, their precursors do not show any appreciable sequence identity and,…”
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Chronic exposure to glufosinate-ammonium induces spatial memory impairments, hippocampal MRI modifications and glutamine synthetase activation in mice by Calas, André-Guilhem, Richard, Olivier, Même, Sandra, Beloeil, Jean-Claude, Doan, Bich-Thuy, Gefflaut, Thierry, Même, William, Crusio, Wim E., Pichon, Jacques, Montécot, Céline

“…Glufosinate-ammonium (GLA), the active compound of a worldwide-used herbicide, acts by inhibiting the plant glutamine synthetase (GS) leading to a lethal…”
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MRI Characterization of Structural Mouse Brain Changes in Response to Chronic Exposure to the Glufosinate Ammonium Herbicide by Meme, Sandra, Calas, André-Guilhem, Montécot, Céline, Richard, Oliver, Gautier, Hélène, Gefflaut, Thierry, Doan, Bich Thuy, Même, William, Pichon, Jacques, Beloeil, Jean-Claude

“…Glufosinate ammonium (GLA) is the active component of herbicides widely used in agriculture, truck farming, or public domains. GLA acts by inhibiting the plant…”
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