Search Results - "Calamante, Gabriela"
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Improving the MVA vaccine potential by deleting the viral gene coding for the IL-18 binding protein
Published in PloS one (22-02-2012)“…Modified Vaccinia Ankara (MVA) is an attenuated strain of Vaccinia virus (VACV) currently employed in many clinical trials against HIV/AIDS and other diseases…”
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IL-12 DNA Displays Efficient Adjuvant Effects Improving Immunogenicity of Ag85A in DNA Prime/MVA Boost Immunizations
Published in Frontiers in cellular and infection microbiology (23-09-2020)“…( ) infection is one of the leading causes of death worldwide. The Modified Vaccinia Ankara (MVA) vaccine vector expressing the mycobacterial antigen 85A…”
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Deletion of A44L, A46R and C12L Vaccinia Virus Genes from the MVA Genome Improved the Vector Immunogenicity by Modifying the Innate Immune Response Generating Enhanced and Optimized Specific T-Cell Responses
Published in Viruses (23-05-2016)“…MVA is an attenuated vector that still retains immunomodulatory genes. We have previously reported its optimization after deleting the C12L gene, coding for…”
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Recombinant canarypox virus expressing the VP2 protein of infectious bursal disease virus induces protection in vaccinated SPF chickens
Published in Virologica Sinica (01-06-2016)“…Dear Editor,Infectious bursal disease virus(IBDV)causes infectious bursal disease,a highly contagious immunosuppressive disease that affects young chickens and…”
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Effect of the US3 protein of bovine herpesvirus 5 on the actin cytoskeleton and apoptosis
Published in Veterinary microbiology (15-12-2011)“…The US3 protein is a unique protein kinase only present in the Alphaherpesvirinae subfamily of the herpesviruses. Studies performed with several…”
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Evaluation of modified vaccinia virus Ankara expressing VP2 protein of infectious bursal disease virus as an immunogen in chickens
Published in Journal of veterinary science (Suwŏn-si, Korea) (01-06-2012)“…A recombinant modified vaccinia Ankara (MVA) virus expressing mature viral protein 2 (VP2) of the infectious bursal disease virus (IBDV) was constructed to…”
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MVAΔ008 viral vector encoding the model protein OVA induces improved immune response against the heterologous antigen and equal levels of protection in a mice tumor model than the conventional MVA
Published in Molecular immunology (01-11-2021)“…•MVAΔ008-OVA induces ex vivo IFN-γ secretion and in vivo cytotoxicity response against OVA.•This response has higher magnitude than the elicited by the…”
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Transgenic Tobacco plants expressing the Potato virus X open reading frame 3 gene develop specific resistance and necrotic ring symptoms after infection with the homologous virus
Published in Molecular plant-microbe interactions (01-11-2001)“…Tobacco plants were transformed with the open reading frame 3 gene from Potato virus X (PVX) coding for the p12 protein. Although the transgenic plants…”
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Superior protection against paratuberculosis by a heterologous prime-boost immunization in a murine model
Published in Vaccine (03-10-2024)“…•MVA85A boost did not improve the immune response induced by 6611 strain + IFA adjuvant.•Priming with 6611 + ISA201 and boosting with MVA85A elicited the…”
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The MVA vector expressing the F protein of bovine respiratory syncytial virus is immunogenic in systemic and mucosal immunization routes
Published in Revista argentina de microbiología (01-04-2024)“…•MVA-F induces BRSV-neutralizing antibodies and in vitro IFN-γ secretion.•This response is higher in a homologous vaccination scheme.•MVA-F administered by the…”
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Comparison of homologous and heterologous prime-boost immunizations combining MVA-vectored and plant-derived VP2 as a strategy against IBDV
Published in Vaccine (03-01-2017)“…Abstract Different immunogens such as subunit, DNA or live viral-vectored vaccines against Infectious Bursal Disease virus (IBDV) have been evaluated in the…”
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Responses of biomarkers of a standardized (Cyprinus carpio) and a native (Pimelodella laticeps) fish species after in situ exposure in a periurban zone of Luján river (Argentina)
Published in Environmental toxicology (01-05-2014)“…The Luján River basin, which is located in the northwest area of the province of Buenos Aires, Argentina, receives different anthropogenic inputs before…”
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Development of Recombinant Canarypox Viruses Expressing Immunogens
Published in Methods in molecular biology (Clifton, N.J.) (2017)“…Canarypox viruses (CNPV) are excellent candidates to develop recombinant vector vaccines due to both their capability to induce protective immune responses and…”
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Identification and molecular characterization of Orf virus in Argentina
Published in Virus genes (01-06-2015)“…Orf virus (ORFV) is the etiological agent of contagious ecthyma (CE), a pustular dermatitis of sheep and goats. Outbreaks of ORFV have been observed in all…”
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Induction of Both Local Immune Response in Mice and Protection in a Rabbit Model by Intranasal Immunization with Modified Vaccinia Ankara Virus Expressing a Secreted Form of Bovine Herpesvirus 1 Glycoprotein D
Published in Viral immunology (01-01-2017)“…In this study, we evaluated the immunogenicity and efficacy of mucosal delivery of a recombinant modified vaccinia Ankara virus (MVA) expressing the secreted…”
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Biomarker responses in caged carp (Cyprinuscarpio) and native collected fish (Leporinus obtusidens) in the Río de la Plata Estuary, Argentina
Published in Environmental toxicology (01-08-2014)“…Punta Lara is located in the Río de la Plata estuary near industrial areas contaminated mainly by organic pollutants. In this work, the responses and status of…”
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Vaccine strategies against Babesia bovis based on prime-boost immunizations in mice with modified vaccinia Ankara vector and recombinant proteins
Published in Vaccine (06-08-2014)“…Highlights • A recombinant MVA vector expressing a multi-antigen of Babesia bovis was obtained. • The MVA was evaluated in prime-boost immunizations with…”
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Vaccine strategies againstBabesia bovisbased on prime-boost immunizations in mice with modified vaccinia Ankara vector and recombinant proteins
Published in Vaccine (06-08-2014)“…In this study, a recombinant modified vaccinia virus Ankara vector expressing a chimeric multi-antigen was obtained and evaluated as a candidate vaccine in…”
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Improved transfection of spleen-derived antigen-presenting cells in culture using TATp-liposomes
Published in Journal of controlled release (20-02-2009)“…Antigen presenting cells (APC) are among the most important cells of the immune system since they link the innate and the adaptative immune responses,…”
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