Search Results - "Calabresi, PA"

IL-6 induces regionally selective spinal cord injury in patients with the neuroinflammatory disorder transverse myelitis by Kaplin, Adam I, Deshpande, Deepa M, Scott, Erick, Krishnan, Chitra, Carmen, Jessica S, Shats, Irina, Martinez, Tara, Drummond, Jennifer, Dike, Sonny, Pletnikov, Mikhail, Keswani, Sanjay C, Moran, Timothy H, Pardo, Carlos A, Calabresi, Peter A, Kerr, Douglas A

“…Transverse myelitis (TM) is an immune-mediated spinal cord disorder associated with inflammation, demyelination, and axonal damage. We investigated the soluble…”
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Quality control for retinal OCT in multiple sclerosis: validation of the OSCAR-IB criteria by Schippling, S, Balk, LJ, Costello, F, Albrecht, P, Balcer, L, Calabresi, PA, Frederiksen, JL, Frohman, E, Green, AJ, Klistorner, A, Outteryck, O, Paul, F, Plant, GT, Traber, G, Vermersch, P, Villoslada, P, Wolf, S, Petzold, A

“…Background: Retinal optical coherence tomography (OCT) permits quantification of retinal layer atrophy relevant to assessment of neurodegeneration in multiple…”
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The genetic diversity of multiple sclerosis risk among Hispanic and African American populations living in the United States by Beecham, AH, Amezcua, L, Chinea, A, Manrique, CP, Rubi, C, Isobe, N, Lund, BT, Santaniello, A, Beecham, GW, Burchard, EG, Comabella, M, Patsopoulos, N, Fitzgerald, K, Calabresi, PA, De Jager, P, Conti, DV, Delgado, SR, Oksenberg, JR, McCauley, JL

“…Background: Substantial progress has been made toward unraveling the genetic architecture of multiple sclerosis (MS) within populations of European ancestry,…”
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Vitamin D status and effect of low-dose cholecalciferol and high-dose ergocalciferol supplementation in multiple sclerosis by Hiremath, GS, Cettomai, D, Baynes, M, Ratchford, JN, Newsome, S, Harrison, D, Kerr, D, Greenberg, BM, Calabresi, PA

“…Background Vitamin D is important for bone health and immune regulation, and has been shown to be low in multiple sclerosis (MS). We sought to determine the…”
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Pegylated interferon beta-1a for relapsing-remitting multiple sclerosis (ADVANCE): a randomised, phase 3, double-blind study by Calabresi, Peter A, Prof, Kieseier, Bernd C, MD, Arnold, Douglas L, Prof, Balcer, Laura J, Prof, Boyko, Alexey, Prof, Pelletier, Jean, MD, Liu, Shifang, PhD, Zhu, Ying, PhD, Seddighzadeh, Ali, MD, Hung, Serena, MD, Deykin, Aaron, MD

“…Summary Background Subcutaneous pegylated interferon (peginterferon) beta-1a is being developed for treatment of relapsing multiple sclerosis, with less…”
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Diagnosis and management of multiple sclerosis by Calabresi, Peter A

“…Multiple sclerosis, an idiopathic inflammatory disease of the central nervous system, is characterized pathologically by demyelination and subsequent axonal…”
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Intensity warping for multisite MRI harmonization by Wrobel, J., Martin, M.L., Bakshi, R., Calabresi, P.A., Elliot, M., Roalf, D., Gur, R.C., Gur, R.E., Henry, R.G., Nair, G., Oh, J., Papinutto, N., Pelletier, D., Reich, D.S., Rooney, W.D., Satterthwaite, T.D., Stern, W., Prabhakaran, K., Sicotte, N.L., Shinohara, R.T., Goldsmith, J.

“…In multisite neuroimaging studies there is often unwanted technical variation across scanners and sites. These “scanner effects” can hinder detection of…”
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Therapeutic Application of Monoclonal Antibodies in Multiple Sclerosis by Orthmann‐Murphy, JL, Calabresi, PA

“…Multiple sclerosis (MS) is a heterogeneous inflammatory demyelinating disorder of the central nervous system (CNS). People with MS typically have a relapsing…”
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Choroid plexus volume differentiates MS from its mimics by Levit, Elle, Ren, Zheng, Gonzenbach, Virgilio, Azevedo, Christina J, Calabresi, Peter A, Cree, Bruce AC, Freeman, Leorah, Longbrake, Erin E, Oh, Jiwon, Schindler, Matthew K, Sicotte, Nancy L, Reich, Daniel S, Ontaneda, Daniel, Sati, Pascal, Cao, Quy, Shinohara, Russell T, Solomon, Andrew J

“…This study aimed to determine whether choroid plexus volume (CPV) could differentiate multiple sclerosis (MS) from its mimics. A secondary analysis of two…”
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The voltage-gated Kv1.3 K+ channel in effector memory T cells as new target for MS by Wulff, Heike, Calabresi, Peter A., Allie, Rameeza, Yun, Sung, Pennington, Michael, Beeton, Christine, Chandy, K. George

“…Through a combination of fluorescence microscopy and patch-clamp analysis we have identified a striking alteration in K + channel expression in terminally…”
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Guidance for use of neurofilament light chain as a cerebrospinal fluid and blood biomarker in multiple sclerosis management by Freedman, Mark S., Gnanapavan, Sharmilee, Booth, Ronald A., Calabresi, Peter A., Khalil, Michael, Kuhle, Jens, Lycke, Jan, Olsson, Tomas

“…Neurofilament light chain (NfL) is a long-awaited blood biomarker that can provide clinically useful information about prognosis and therapeutic efficacy in…”
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Relation of visual function to retinal nerve fiber layer thickness in multiple sclerosis by Fisher, Jennifer B, Jacobs, Dina A, Markowitz, Clyde E, Galetta, Steven L, Volpe, Nicholas J, Nano-Schiavi, M Ligia, Baier, Monika L, Frohman, Elliot M, Winslow, Heather, Frohman, Teresa C, Calabresi, Peter A, Maguire, Maureen G, Cutter, Gary R, Balcer, Laura J

“…To examine the relation of visual function to retinal nerve fiber layer (RNFL) thickness as a structural biomarker for axonal loss in multiple sclerosis (MS),…”
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MRI of the corpus callosum in multiple sclerosis: association with disability by Ozturk, A., Smith, SA, Gordon-Lipkin, EM, Harrison, DM, Shiee, N., Pham, DL, Caffo, BS, Calabresi, PA, Reich, DS

“…Inflammatory demyelination and axon damage in the corpus callosum are prominent features of multiple sclerosis (MS) and may partially account for impaired…”
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Spotlight on Trans-Synaptic Degeneration in the Visual Pathway in Multiple Sclerosis by Filippatou, Angeliki G, Calabresi, Peter A, Saidha, Shiv, Murphy, Olwen C

“…A putative mechanism of neurodegeneration in multiple sclerosis (MS) is trans-synaptic degeneration (TSD), whereby injury to a neuron leads to degeneration of…”
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Targeting effector memory T cells with a selective peptide inhibitor of Kv1.3 channels for therapy of autoimmune diseases by Beeton, Christine, Pennington, Michael W, Wulff, Heike, Singh, Satendra, Nugent, Daniel, Crossley, George, Khaytin, Ilya, Calabresi, Peter A, Chen, Chao-Yin, Gutman, George A, Chandy, K George

“…The voltage-gated Kv1.3 K(+) channel is a novel target for immunomodulation of autoreactive effector memory T (T(EM)) cells that play a major role in the…”
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Idiopathic transverse myelitis : Corticosteroids, plasma exchange, or cyclophosphamide by GREENBERG, B. M, THOMAS, K. P, KRISHNAN, C, KAPLIN, A. I, CALABRESI, P. A, KERR, D. A

“…Transverse myelitis is a focal disorder of the spinal cord in which an immune-mediated process results in neural injury. In this large retrospective study, we…”
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Association of Vitamin D Polygenic Risk Scores and Disease Outcome in People With Multiple Sclerosis by Vasileiou, Eleni S., Hu, Chen, Bernstein, Charles N., Lublin, Fred, Wolinsky, Jerry S., Cutter, Gary R., Sotirchos, Elias S., Kowalec, Kaarina, Salter, Amber, Saidha, Shiv, Mowry, Ellen M., Calabresi, Peter A., Marrie, Ruth Ann, Fitzgerald, Kathryn C.

“…BACKGROUND AND OBJECTIVESObservational studies suggest low levels of 25-hydroxyvitamin D (25[OH]D) may be associated with increased disease activity in people…”
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The Voltage-Gated Potassium Channel Kv1.3 Is Highly Expressed on Inflammatory Infiltrates in Multiple Sclerosis Brain by Rus, Horea, Pardo, Carlos A., Hu, Lina, Darrah, Erika, Cudrici, Cornelia, Niculescu, Teodora, Niculescu, Florin, Mullen, Katharine M., Allie, Rameeza, Guo, Liping, Wulff, Heike, Beeton, Christine, Susan I. V. Judge, Kerr, Douglas A., Knaus, Hans-Gunther, Chandy, K. George, Calabresi, Peter A., Latorre, Ramon

“…Multiple Sclerosis (MS) is characterized by central nervous system perivenular and parenchymal mononuclear cell infiltrates consisting of activated T cells and…”
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Cleavage of cystatin C in the cerebrospinal fluid of patients with multiple sclerosis by Irani, David N., Anderson, Caroline, Gundry, Rebekah, Cotter, Robert, Moore, Stacy, Kerr, Douglas A., McArthur, Justin C., Sacktor, Ned, Pardo, Carlos A., Jones, Melina, Calabresi, Peter A., Nath, Avindra

“…Objective The diagnosis of multiple sclerosis (MS) can be challenging because of the lack of a specific diagnostic test. Recent advances in proteomics,…”
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Considerations in the treatment of relapsing-remitting multiple sclerosis by Calabresi, Peter A

“…Disease-modifying drugs are available in the United States for the treatment of relapsing-remitting multiple sclerosis (RRMS), including interferon (IFN)…”
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