Search Results - "Cajigas, Ivelisse"

Evf2 (Dlx6as) lncRNA regulates ultraconserved enhancer methylation and the differential transcriptional control of adjacent genes by Berghoff, Emily G, Clark, Mary F, Chen, Sean, Cajigas, Ivelisse, Leib, David E, Kohtz, Jhumku D

“…Several lines of evidence suggest that long non-coding RNA (lncRNA)-dependent mechanisms regulate transcription and CpG DNA methylation. Whereas CpG island…”
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The Evf2 Ultraconserved Enhancer lncRNA Functionally and Spatially Organizes Megabase Distant Genes in the Developing Forebrain by Cajigas, Ivelisse, Chakraborty, Abhijit, Swyter, Kelsey R., Luo, Hao, Bastidas, Monique, Nigro, Maximilliano, Morris, Elizabeth R., Chen, Sean, VanGompel, Michael J.W., Leib, David, Kohtz, Sara J., Martina, Marco, Koh, Sooky, Ay, Ferhat, Kohtz, Jhumku D.

“…Gene regulation requires selective targeting of DNA regulatory enhancers over megabase distances. Here we show that Evf2, a cloud-forming Dlx5/6 ultraconserved…”
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Epigenetic Transcriptional Memory of GAL Genes Depends on Growth in Glucose and the Tup1 Transcription Factor in Saccharomyces cerevisiae by Sood, Varun, Cajigas, Ivelisse, D'Urso, Agustina, Light, William H, Brickner, Jason H

“…Previously expressed inducible genes can remain poised for faster reactivation for multiple cell divisions, a conserved phenomenon called epigenetic…”
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H2A.Z-mediated localization of genes at the nuclear periphery confers epigenetic memory of previous transcriptional state by Brickner, Donna Garvey, Cajigas, Ivelisse, Fondufe-Mittendorf, Yvonne, Ahmed, Sara, Lee, Pei-Chih, Widom, Jonathan, Brickner, Jason H

“…Many genes are recruited to the nuclear periphery upon transcriptional activation. The mechanism and functional significance of this recruitment is unclear. We…”
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Sox2- Evf2 lncRNA-mediated mechanisms of chromosome topological control in developing forebrain by Cajigas, Ivelisse, Chakraborty, Abhijit, Lynam, Madison, Swyter, Kelsey R, Bastidas, Monique, Collens, Linden, Luo, Hao, Ay, Ferhat, Kohtz, Jhumku D

“…The long non-coding RNA directs ultraconserved enhancer( )-intrachromosomal interactions, regulating genes across a 27 Mb region on chromosome 6 in mouse…”
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Evf2 lncRNA/BRG1/DLX1 interactions reveal RNA-dependent inhibition of chromatin remodeling by Cajigas, Ivelisse, Leib, David E, Cochrane, Jesse, Luo, Hao, Swyter, Kelsey R, Chen, Sean, Clark, Brian S, Thompson, James, Yates, 3rd, John R, Kingston, Robert E, Kohtz, Jhumku D

“…Transcription-regulating long non-coding RNAs (lncRNAs) have the potential to control the site-specific expression of thousands of target genes. Previously, we…”
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DNA zip codes control an ancient mechanism for gene targeting to the nuclear periphery by Cajigas, Ivelisse, Brickner, Jason H, Brickner, Donna G, Light, William H, Froyshteter, Alexander B, Ahmed, Sara, McDonough, Michele, Volpe, Tom

“…In budding yeast, many inducible genes translocate to the nuclear periphery when activated. Sequence motifs have now been identified in promoters, which target…”
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The Evf2 enhancer long noncoding RNA regulates enhancer interactions across megabase distances by Kohtz, Jhumku, Cajigas, Ivelisse, Chakraborty, Abhijit, Bastidas, Monique, Swyter, Kelsey S., Kohtz, Sara J., Ay, Ferhat

“…A major question in genome biology is how genes are selectively targeted and regulated over megabase (Mb) distances in the genome. In this work, we show that…”
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The Evf2 enhancer lncRNA links chromosomal interactions and interneuron diversity by Kohtz, Jhumku, Cajigas, Ivelisse, Swyter, Kelsey R, Bastidas, Monique, Chakraborty, Abhijit, Morris, Elizabeth, Ay, Ferhat

“…Understanding how genes are selectively regulated during development is a major goal in biology. While DNA enhancers selectively regulate genes at a distance,…”
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SHH E176/E177-Zn2+ conformation is required for signaling at endogenous sites by Himmelstein, Diana S., Cajigas, Ivelisse, Bi, Chunming, Clark, Brian S., Van Der Voort, Grant, Kohtz, Jhumku D.

“…Sonic hedgehog (SHH) is a master developmental regulator. In 1995, the SHH crystal structure predicted that SHH-E176 (human)/E177 (mouse) regulates signaling…”
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The Evf2 ultraconserved enhancer lncRNA functionally and spatially organizes multi-megabase distant genes in developing forebrain by Cajigas, Ivelisse, Chakraborty, Abhijit, Swyter, Kelsey R., Luo, Hao, Bastidas, Monique, Nigro, Maximilliano, Morris, Elizabeth R., Chen, Sean, VanGompel, Michael J. W., Leib, David, Kohtz, Sara J., Martina, Marco, Koh, Sooky, Ay, Ferhat, Kohtz, Jhumku D.

“…Gene regulation requires selective targeting of DNA regulatory enhancers over megabase (Mb) distances. Here, we show that Evf2 , a cloud-forming Dlx5/6…”
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Evf2 lncRNA /BRG1/DLX1 interactions reveal RNA-dependent chromatin remodeling inhibition by Cajigas, Ivelisse, Leib, David E., Cochrane, Jesse, Luo, Hao, Swyter, Kelsey, Chen, Sean, Clark, Brian S., Thompson, James, Yates, John R., Kingston, Robert E., Kohtz, Jhumku D.

“…Transcription-regulating long non-coding RNAs (lncRNAs) have the potential to control site-specific gene expression of thousands of targets. Previously, we…”
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Histone H2B ubiquitylation and H3 lysine 4 methylation prevent ectopic silencing of euchromatic loci important for the cellular response to heat by Leung, Amy, Cajigas, Ivelisse, Jia, Peilin, Ezhkova, Elena, Brickner, Jason H, Zhao, Zhongming, Geng, Fuqiang, Tansey, William P

“…In Saccharomyces cerevisiae, ubiquitylation of histone H2B signals methylation of histone H3 at lysine residues 4 (K4) and 79. These modifications occur at…”
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SHH E176/E177-Zn 2+ conformation is required for signaling at endogenous sites by Himmelstein, Diana S, Cajigas, Ivelisse, Bi, Chunming, Clark, Brian S, Van Der Voort, Grant, Kohtz, Jhumku D

“…Sonic hedgehog (SHH) is a master developmental regulator. In 1995, the SHH crystal structure predicted that SHH-E176 (human)/E177 (mouse) regulates signaling…”
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Erratum: DNA zip codes control an ancient mechanism for gene targeting to the nuclear periphery by Ahmed, Sara, Brickner, Donna G., Light, William H., Cajigas, Ivelisse, McDonough, Michele, Froyshteter, Alexander B., Volpe, Tom, Brickner, Jason H.

“…Nature Cell Biol. 12, 111–118 (2010); published online 24 January 2010; corrected after print, 27 January 2010 In the version of this Article initially…”
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Alternative Splicing Suggests Extended Function of PEX26 in Peroxisome Biogenesis by Weller, Sabine, Cajigas, Ivelisse, Morrell, James, Obie, Cassandra, Steel, Gary, Gould, Stephen J., Valle, David

“…Matsumoto and colleagues recently identified PEX26 as the gene responsible for complementation group 8 of the peroxisome biogenesis disorders and showed that…”
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Multiple Independent Inputs Modulate Epigenetic GAL Gene Transcriptional Memory by Cajigas, Ivelisse

“…Yeast cells “remember”previous expression of certain genes, priming them for faster reactivation for generations after they have been repressed. GAL genes that…”
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DNA zip codes control an ancient mechanism for gene targeting to the nuclear periphery by Ahmed, Sara, Brickner, Donna G, Light, William H, Cajigas, Ivelisse, McDonough, Michele, Froyshteter, Alexander B, Volpe, Tom, Brickner, Jason H

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Optimization of Spider Silk Glands for the Elicited Production of a Tissue‐Specific Fibroin Product by Marrero, Brenda Marie, Cajigas, Ivelisse, Cajigas, Xiomara, Medina, Shadia, Llavona, Marcos, Alameda, Annette, Ortiz, Nicole, Candelas, Graciela C.

“…Through simple manipulations, we have been able to virtually abolish the production of a fibroin by a pair of spider glands, and subsequently elicit the…”
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Multiple Independent Inputs Modulate Epigenetic GAL Gene Transcriptional Memory by Cajigas, Ivelisse

“…Yeast cells "remember"previous expression of certain genes, priming them for faster reactivation for generations after they have been repressed. GAL genes that…”
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