Search Results - "Cairns, M.J."

S.08.04 MicroRNA in schizophrenia and developmental disorders by Cairns, M.J

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Genome-wide mRNA and miRNA analysis of peripheral blood mononuclear cells (PBMC) reveals different miRNAs regulating HIV/HCV co-infection by Gupta, P, Liu, B, Wu, J.Q, Soriano, V, Vispo, E, Carroll, A.P, Goldie, B.J, Cairns, M.J, Saksena, N.K

“…Abstract Co-infection with human immunodeficiency virus (HIV) and hepatitis C virus (HCV) is common due to shared transmission routes. The genomic basis of…”
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Circular RNAs are temporospatially regulated throughout development and ageing in the rat by Mahmoudi, E., Cairns, M. J.

“…Circular RNAs (circRNAs) are covalently closed structural isoforms of linear mRNA which have been observed across a broad range of species and tissues. Here,…”
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Schizophrenia is associated with an increase in cortical microRNA biogenesis by Beveridge, N J, Gardiner, E, Carroll, A P, Tooney, P A, Cairns, M J

“…MicroRNA expression profiling and quantitative reverse transcription-PCR analysis of the superior temporal gyrus and the dorsolateral prefrontal cortex…”
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Imprinted DLK1-DIO3 region of 14q32 defines a schizophrenia-associated miRNA signature in peripheral blood mononuclear cells by Gardiner, E, Beveridge, N J, Wu, J Q, Carr, V, Scott, R J, Tooney, P A, Cairns, M J

“…MicroRNAs (miRNAs) regulate gene expression at the post-transcriptional level and are important for coordinating nervous system development and neuronal…”
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The long non-coding RNA Gomafu is acutely regulated in response to neuronal activation and involved in schizophrenia-associated alternative splicing by Barry, G, Briggs, J A, Vanichkina, D P, Poth, E M, Beveridge, N J, Ratnu, V S, Nayler, S P, Nones, K, Hu, J, Bredy, T W, Nakagawa, S, Rigo, F, Taft, R J, Cairns, M J, Blackshaw, S, Wolvetang, E J, Mattick, J S

“…Schizophrenia (SZ) is a complex disease characterized by impaired neuronal functioning. Although defective alternative splicing has been linked to SZ, the…”
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Genome-wide supported variant MIR137 and severe negative symptoms predict membership of an impaired cognitive subtype of schizophrenia by Green, M J, Cairns, M J, Wu, J, Dragovic, M, Jablensky, A, Tooney, P A, Scott, R J, Carr, V J

“…Progress in determining the aetiology of schizophrenia (Sz) has arguably been limited by a poorly defined phenotype. We sought to delineate empirically derived…”
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Genome-wide supported variant MIR137 and severe negative symptoms predict membership of an impaired cognitive subtype of schizophrenia by Green, M.J, Cairns, M.J, Wu, J, Dragovic, M, Jablensky, A, Tooney, P.A, Scott, R.J, Carr, V.J

“…Progress in determining the aetiology of schizophrenia (Sz) has arguably been limited by a poorly defined phenotype. We sought to delineate empirically derived…”
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Target site selection for an RNA-cleaving catalytic DNA by Sun, Lun-Quan, Cairns, Murray J, Hopkins, Toni M, Witherington, Craig, Wang, Li

“…A small catalytic DNA, known as the 10-23 DNA enzyme or deoxyribozyme, has been shown to efficiently hydrolyze RNA at purine-pyrimidine (R-Y) junctions in…”
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Physiological and pathophysiological influences on thirst by McKinley, M.J., Cairns, M.J., Denton, D.A., Egan, G., Mathai, M.L., Uschakov, A., Wade, J.D., Weisinger, R.S., Oldfield, B.J.

“…Thirst motivates animals to seek fluid and drink it. It is regulated by the central nervous system and arises from neural and chemical signals from the…”
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Catalytic DNA: a novel tool for gene suppression by Cairns, M J, Saravolac, E G, Sun, L Q

“…RNA, as an intermediate in the production of every gene encoded protein and the genetic material of many pathogenic viruses, presents an attractive target for…”
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