Search Results - "Cairns, John"

The International Decision Support Initiative Reference Case for Economic Evaluation: An Aid to Thought by Wilkinson, Thomas, MSc, Sculpher, Mark J., PhD, Claxton, Karl, PhD, Revill, Paul, MSc, Briggs, Andrew, DPhil, Cairns, John A., MPhil, Teerawattananon, Yot, PhD, Asfaw, Elias, MSc, Lopert, Ruth, MD, MMedSc, Culyer, Anthony J., BA, Hon DEcon, Walker, Damian G., PhD

“…Abstract Background Policymakers in high-, low-, and middle-income countries alike face challenging choices about resource allocation in health. Economic…”
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Exploring uncertainty and use of real-world data in the National Institute for Health and Care Excellence single technology appraisals of targeted cancer therapy by Kang, Jiyeon, Cairns, John

“…Dealing with uncertainty is one of the critical topics in health technology assessment. The greater decision uncertainty in appraisals, the less clear the…”
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Do cancer biomarkers make targeted therapies cost-effective? A systematic review in metastatic colorectal cancer by Seo, Mikyung Kelly, Cairns, John

“…Recent advances in targeted therapies have raised expectations that the clinical application of biomarkers would improve patient's health outcomes and…”
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2014 Focused Update of the Canadian Cardiovascular Society Guidelines for the Management of Atrial Fibrillation by Verma, Atul, MD, Cairns, John A., MD, Mitchell, L. Brent, MD, Macle, Laurent, MD, Stiell, Ian G., MD, Gladstone, David, MD, McMurtry, Michael Sean, MD, Connolly, Stuart, MD, Cox, Jafna L., MD, Dorian, Paul, MD, Ivers, Noah, MD, Leblanc, Kori, PharmD, Nattel, Stanley, MD, Healey, Jeff S., MD

“…Abstract Atrial fibrillation (AF) is an extremely common clinical problem with an important population morbidity and mortality burden. The management of AF is…”
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How are we evaluating the cost-effectiveness of companion biomarkers for targeted cancer therapies? A systematic review by Seo, Mikyung Kelly, Cairns, John

“…Abstract Background Despite the increasing economic assessment of biomarker-guided therapies, no clear agreement exists whether existing methods are sufficient…”
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The 2020 Canadian Cardiovascular Society/Canadian Heart Rhythm Society Comprehensive Guidelines for the Management of Atrial Fibrillation by Andrade, Jason G., Aguilar, Martin, Atzema, Clare, Bell, Alan, Cairns, John A., Cheung, Christopher C., Cox, Jafna L., Dorian, Paul, Gladstone, David J., Healey, Jeff S., Khairy, Paul, Leblanc, Kori, McMurtry, M. Sean, Mitchell, L. Brent, Nair, Girish M., Nattel, Stanley, Parkash, Ratika, Pilote, Louise, Sandhu, Roopinder K., Sarrazin, Jean-François, Sharma, Mukul, Skanes, Allan C., Talajic, Mario, Tsang, Teresa S.M., Verma, Atul, Verma, Subodh, Whitlock, Richard, Wyse, D. George, Macle, Laurent

“…The Canadian Cardiovascular Society (CCS) atrial fibrillation (AF) guidelines program was developed to aid clinicians in the management of these complex…”
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A systematic literature review of health state utility values in head and neck cancer by Meregaglia, Michela, Cairns, John

“…Health state utility values (HSUVs) are essential parameters in model-based economic evaluations. This study systematically identifies HSUVs in head and neck…”
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Cross-sectional analysis of use of real-world data in single technology appraisals of oncological medicine by the National Institute for Health and Care Excellence in 2011–2021 by Kang, Jiyeon, Cairns, John

“…ObjectivesThis study aims to identify how real-world data (RWD) have been used in single technology appraisals (STAs) of cancer drugs by the National Institute…”
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Complete Revascularization with Multivessel PCI for Myocardial Infarction by Mehta, Shamir R, Wood, David A, Storey, Robert F, Mehran, Roxana, Bainey, Kevin R, Nguyen, Helen, Meeks, Brandi, Di Pasquale, Giuseppe, López-Sendón, Jose, Faxon, David P, Mauri, Laura, Rao, Sunil V, Feldman, Laurent, Steg, P. Gabriel, Avezum, Álvaro, Sheth, Tej, Pinilla-Echeverri, Natalia, Moreno, Raul, Campo, Gianluca, Wrigley, Benjamin, Kedev, Sasko, Sutton, Andrew, Oliver, Richard, Rodés-Cabau, Josep, Stanković, Goran, Welsh, Robert, Lavi, Shahar, Cantor, Warren J, Wang, Jia, Nakamya, Juliet, Bangdiwala, Shrikant I, Cairns, John A

“…Patients with ST-segment elevation MI and multivessel coronary disease who had undergone successful culprit-lesion PCI were assigned to a strategy of either…”
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Trends in Prescribing Oral Anticoagulants in Canada, 2008–2014 by Weitz, Jeffrey I., MD, Semchuk, William, MSc, PharmD, Turpie, Alexander G.G., MD, Fisher, William D., MD, Kong, Cindy, BRE, Ciaccia, Antonio, MSc, Cairns, John A., MD

“…Abstract Purpose The non–vitamin K antagonist oral anticoagulants (NOACs), dabigatran, rivaroxaban, and apixaban, provide several advantages over vitamin K…”
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Protocol for data extraction: how real-world data have been used in the National Institute for Health and Care Excellence appraisals of cancer therapy by Kang, Jiyeon, Cairns, John

“…IntroductionDue to the limitations of relying on randomised controlled trials, the potential benefits of real-world data (RWD) in enriching evidence for health…”
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Thrombus Aspiration in ST-Segment–Elevation Myocardial Infarction: An Individual Patient Meta-Analysis: Thrombectomy Trialists Collaboration by Jolly, Sanjit S., James, Stefan, Džavík, Vladimír, Cairns, John A., Mahmoud, Karim D., Zijlstra, Felix, Yusuf, Salim, Olivecrona, Goran K., Renlund, Henrik, Gao, Peggy, Lagerqvist, Bo, Alazzoni, Ashraf, Kedev, Sasko, Stankovic, Goran, Meeks, Brandi, Frøbert, Ole

“…BACKGROUND:Thrombus aspiration during percutaneous coronary intervention (PCI) for the treatment of ST-segment–elevation myocardial infarction (STEMI) has been…”
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Focused 2012 Update of the Canadian Cardiovascular Society Atrial Fibrillation Guidelines: Recommendations for Stroke Prevention and Rate/Rhythm Control by Skanes, Allan C., MD, FRCPC, Healey, Jeff S., MD, MSc, FRCPC, Cairns, John A., MD, FRCPC, Dorian, Paul, MD, FRCPC, Gillis, Anne M., MD, FRCPC, McMurtry, M. Sean, MD, PhD, FRCPC, Mitchell, L. Brent, MD, FRCPC, Verma, Atul, MD, FRCPC, Nattel, Stanley, MD, FRCPC

“…Abstract The Canadian Cardiovascular Society (CCS) published the complete set of 2010 Atrial Fibrillation (AF) Guidelines in the January, 2011 issue of the…”
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Evidence Quality and Health Technology Assessment Outcomes in Reappraisals of Drugs for Rare Diseases in Germany by Wiedmann, Lea A., Cairns, John A., Nolte, Ellen

“…Evidence on reappraisals of health technologies in Germany is limited, and for rare disease treatments (RDTs), the Federal Joint Committee follows different…”
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Contemporary Atrial Fibrillation Management – A comparison of the current AHA/ACC/HRS, CCS, and ESC guidelines by Andrade, Jason G., MD, Macle, Laurent, MD, Nattel, Stanley, MD, Verma, Atul, MD, Cairns, John, MD

“…Abstract This article compares and contrasts the current recommendations, and highlights the important differences, in the American College of Cardiology…”
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Quality of life among women with symptomatic, screen-detected, and interval breast cancer, and for women without breast cancer: a retrospective cross-sectional study from Norway by Moshina, Nataliia, Falk, Ragnhild S., Botteri, Edoardo, Larsen, Marthe, Akslen, Lars A., Cairns, John A., Hofvind, Solveig

“…Purpose Breast cancers detected at screening need less aggressive treatment compared to breast cancers detected due to symptoms. The evidence on the quality of…”
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The cost-effectiveness of smoking cessation support delivered by mobile phone text messaging: Txt2stop by Guerriero, Carla, Cairns, John, Roberts, Ian, Rodgers, Anthony, Whittaker, Robyn, Free, Caroline

“…Background The txt2stop trial has shown that mobilephone-based smoking cessation support doubles biochemically validated quitting at 6 months. This study…”
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2016 Focused Update of the Canadian Cardiovascular Society Guidelines for the Management of Atrial Fibrillation by Macle, Laurent, MD, Cairns, John, MD, Leblanc, Kori, PharmD, Tsang, Teresa, MD, Skanes, Allan, MD, Cox, Jafna L., MD, Healey, Jeff S., MD, Bell, Alan, MD, Pilote, Louise, MD, Andrade, Jason G., MD, Mitchell, L. Brent, MD, Atzema, Clare, MD, Gladstone, David, MD, Sharma, Mike, MD, Verma, Subodh, MD, Connolly, Stuart, MD, Dorian, Paul, MD, Parkash, Ratika, MD, Talajic, Mario, MD, Nattel, Stanley, MD, Verma, Atul, MD

“…Abstract The Canadian Cardiovascular Society (CCS) Atrial Fibrillation (AF) Guidelines Committee provides periodic reviews of new data to produce focused…”
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The search for the ideal atrial fibrillation stroke risk prediction schema: is ATRIA a contender? by Cairns, John A

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Somatic Stem Cells and the Kinetics of Mutagenesis and Carcinogenesis by Cairns, John

“…There is now strong experimental evidence that epithelial stem cells arrange their sister chromatids at mitosis such that the same template DNA strands stay…”
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