Search Results - "Cain, Brian M."

Transport characterization of membranes for immunoisolation by Dionne, Keith E., Cain, Brian M., Li, Rebecca H., Bell, William J., Doherty, Edward j., Rein, David H., Lysaght, Michael J., Gentile, Frank T.

“…This study relates to the diffusive transport characterization of hollow fibre membranes used in implantable bio-hybrid organs and other immunoisolatory…”
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Production, Purification, and Characterization of Recombinant Prohormone Convertase 5 from Baculovirus-Infected Insect Cells by Cain, Brian M, Vishnuvardhan, Daesety, Wang, Wenge, Foulon, Thierry, Cadel, Sandrine, Cohen, Paul, Beinfeld, Margery C

“…The discovery of the prohormone convertase (PC) family of enzymes has provided several good candidates (PC1, PC2, and PC5) for the enzymes responsible for the…”
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Distribution and colocalization of cholecystokinin with the prohormone convertase enzymes PC1, PC2, and PC5 in rat brain by Cain, Brian M., Connolly, Kelly, Blum, Alissa, Vishnuvardham, Daesety, Marchand, James E., Beinfeld, Margery C.

“…During posttranslational processing to generate CCK 8, pro‐cholecystokinin (CCK) undergoes endoproteolytic cleavage at three sites. Several studies using…”
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Cholecystokinin (CCK) Levels Are Greatly Reduced in the Brains But Not the Duodenums of Cpefat/Cpefat Mice: A Regional Difference in the Involvement of Carboxypeptidase E (Cpe) in Pro-CCK Processing by Cain, Brian M, Wang, Wenge, Beinfeld, Margery C

“…In order to assess the possible role of carboxypeptidase E (Cpe) in pro-CCK processing, tissues from the Cpefat/Cpefat mice were analyzed for CCK content and…”
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Cholecystokinin (CCK) levels are greatly reduced in the brains but not the duodenums of Cpe(fat)/Cpe(fat) mice: a regional difference in the involvement of carboxypeptidase E (Cpe) in pro-CCK processing by Cain, B M, Wang, W, Beinfeld, M C

“…In order to assess the possible role of carboxypeptidase E (Cpe) in pro-CCK processing, tissues from the Cpe(fat)/Cpe(fat) mice were analyzed for CCK content…”
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Neuronal cell lines expressing PC5, but not PC1 or PC2, process Pro-CCK into glycine-extended CCK 12 and 22 by Cain, Brian M., Vishnuvardhan, Daesety, Beinfeld, Margery C.

“…Endocrine tumor cells in culture and in vitro cleavage assays have shown that PC1 and PC2 are capable of processing pro-CCK into smaller, intermediate and…”
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Adult carboxypeptidase E-deficient fat/fat mice have a near-total depletion of brain CCK 8 accompanied by a massive accumulation of glycine and arginine extended CCK: identification of CCK 8 Gly as the immediate precursor of CCK 8 in rodent brain by Wang, W, Cain, B M, Beinfeld, M C

“…Cholecystokinin (CCK) amide concentrations were reduced over 85% in all the major brain regions of carboxypeptidase E (Cpe)(fat)/Cpe(fat) mice in comparison to…”
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The Physiologic Basis for Anticytokine Clinical Trials in the Treatment of Sepsis 1 by Cain MD, Brian S, Meldrum MD, Daniel R, Harken MD, FACS, Alden H, McIntyre Jr, MD, FACS, Robert C

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Adult carboxypeptidase E-deficient fat/fat mice have a near-total depletion of brain CCK 8 accompanied by a massive accumulation of glycine and arginine extended CCK by Wang, Wenge, Cain, Brian M, Beinfeld Margery C Dr

“…Cholecystokinin (CCK) amide concentrations were reduced over 85% in all the major brain regions of carboxypeptidase E (Cpe)fat/Cpefat mice in comparison to…”
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