Search Results - "Cain, Brian D."

The circadian clock protein Period 1 regulates expression of the renal epithelial sodium channel in mice by Gumz, Michelle L, Stow, Lisa R, Lynch, I Jeanette, Greenlee, Megan M, Rudin, Alicia, Cain, Brian D, Weaver, David R, Wingo, Charles S

“…The mineralocorticoid aldosterone is a major regulator of sodium transport in target epithelia and contributes to the control of blood pressure and cardiac…”
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The Circadian Protein Period 1 Contributes to Blood Pressure Control and Coordinately Regulates Renal Sodium Transport Genes by Stow, Lisa R, Richards, Jacob, Cheng, Kit-Yan, Lynch, I Jeanette, Jeffers, Lauren A, Greenlee, Megan M, Cain, Brian D, Wingo, Charles S, Gumz, Michelle L

“…The circadian clock protein period 1 (Per1) contributes to the regulation of expression of the α subunit of the renal epithelial sodium channel at the basal…”
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The renal H+-K+-ATPases: physiology, regulation, and structure by Gumz, Michelle L, Lynch, I Jeanette, Greenlee, Megan M, Cain, Brian D, Wingo, Charles S

“…The H(+)-K(+)-ATPases are ion pumps that use the energy of ATP hydrolysis to transport protons (H(+)) in exchange for potassium ions (K(+)). These enzymes…”
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Two rotary motors in F-ATP synthase are elastically coupled by a flexible rotor and a stiff stator stalk by Wächter, André, Bi, Yumin, Dunn, Stanley D, Cain, Brian D, Sielaff, Hendrik, Wintermann, Frank, Engelbrecht, Siegfried, Junge, Wolfgang

“…ATP is synthesized by ATP synthase (FOF₁-ATPase). Its rotary electromotor (FO) translocates protons (in some organisms sodium cations) and generates torque to…”
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EDN1-AS , A Novel Long Non-coding RNA Regulating Endothelin-1 in Human Proximal Tubule Cells by Douma, Lauren G, Solocinski, Kristen, Masten, Sarah H, Barral, Dominique H, Barilovits, Sarah J, Jeffers, Lauren A, Alder, Kareme D, Patel, Ravi, Wingo, Charles S, Brown, Kevin D, Cain, Brian D, Gumz, Michelle L

“…Endothelin-1 (ET-1) is a peptide hormone that functions as a vasoconstrictor in the vasculature, whereas in the collecting duct of the kidney it exerts blood…”
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Aldosterone Modulates Steroid Receptor Binding to the Endothelin-1 Gene (edn1) by Stow, Lisa R., Gumz, Michelle L., Lynch, I.Jeanette, Greenlee, Megan M., Rudin, Alicia, Cain, Brian D., Wingo, Charles S.

“…Aldosterone and endothelin-1 (ET-1) act on collecting duct cells of the kidney and are important regulators of renal sodium transport and cardiovascular…”
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Functional expression of human adenine nucleotide translocase 4 in Saccharomyces cerevisiae by Hamazaki, Takashi, Leung, Wai-Yee, Cain, Brian D, Ostrov, David A, Thorsness, Peter E, Terada, Naohiro

“…The adenine nucleotide translocase (ANT) mediates the exchange of ADP and ATP across the inner mitochondrial membrane. The human genome encodes multiple ANT…”
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An emerging role for microRNA in the regulation of endothelin-1 by Jacobs, Mollie E, Wingo, Charles S, Cain, Brian D

“…Endothelin-1 (ET-1) is a peptide signaling molecule serving diverse functions in many different tissues such as the vasculature and the kidney. The primary…”
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Early transcriptional effects of aldosterone in a mouse inner medullary collecting duct cell line by Gumz, Michelle L, Popp, Michael P, Wingo, Charles S, Cain, Brian D

“…The mineralocorticoid aldosterone is a major regulator of Na+ and acid-base balance and control of blood pressure. Although the long-term effects of…”
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Endothelin-1 gene regulation by Stow, Lisa R, Jacobs, Mollie E, Wingo, Charles S, Cain, Brian D

“…Over two decades of research have demonstrated that the peptide hormone endothelin-1 (ET-1) plays multiple, complex roles in cardiovascular, neural, pulmonary,…”
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The b Subunits in the Peripheral Stalk of F1F0 ATP Synthase Preferentially Adopt an Offset Relationship by Claggett, Shane B., Plancher, Mac O'Neil, Dunn, Stanley D., Cain, Brian D.

“…The peripheral stalk of F1F0 ATP synthase is essential for the binding of F1 to FO and for proper transfer of energy between the two sectors of the enzyme. The…”
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Female C57BL/6J mice lacking the circadian clock protein PER1 are protected from nondipping hypertension by Douma, Lauren G, Solocinski, Kristen, Holzworth, Meaghan R, Crislip, G Ryan, Masten, Sarah H, Miller, Amber H, Cheng, Kit-Yan, Lynch, I Jeanette, Cain, Brian D, Wingo, Charles S, Gumz, Michelle L

“…The circadian clock is integral to the maintenance of daily rhythms of many physiological outputs, including blood pressure. Our laboratory has previously…”
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Renal Na-handling defect associated with PER1-dependent nondipping hypertension in male mice by Douma, Lauren G, Holzworth, Meaghan R, Solocinski, Kristen, Masten, Sarah H, Miller, Amber H, Cheng, Kit-Yan, Lynch, I Jeanette, Cain, Brian D, Wingo, Charles S, Gumz, Michelle L

“…Many physiological functions have a circadian rhythm, including blood pressure (BP). BP is highest during the active phase, whereas during the rest period, BP…”
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Functional Incorporation of Chimeric b Subunits into F1Fo ATP Synthase by Claggett, Shane B, Grabar, Tammy Bohannon, Dunn, Stanley D, Cain, Brian D

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Integration of b Subunits of Unequal Lengths into F1F0-ATP Synthase by Grabar, Tammy Bohannon, Cain, Brian D.

“…In Escherichia coli the peripheral stalk of F1F0-ATP synthase consists of a parallel dimer of identical b subunits. However, the length of the two b subunits…”
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Tissue-specific and time-dependent regulation of the endothelin axis by the circadian clock protein Per1 by Richards, Jacob, Welch, Amanda K., Barilovits, Sarah J., All, Sean, Cheng, Kit-Yan, Wingo, Charles S., Cain, Brian D., Gumz, Michelle L.

“…The present study is designed to consider a role for the circadian clock protein Per1 in the regulation of the endothelin axis in mouse kidney, lung, liver and…”
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Genetic Complementation between Mutant b Subunits in F1F0 ATP Synthase by Grabar, Tammy Bohannon, Cain, Brian D

“…In Escherichia coli , a parallel homodimer of identical b subunits constitutes the peripheral stalk of F 1 F 0 ATP synthase. Although the two b subunits have…”
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Endothelin-1 inhibits sodium reabsorption by ET(A) and ET(B) receptors in the mouse cortical collecting duct by Lynch, I Jeanette, Welch, Amanda K, Kohan, Donald E, Cain, Brian D, Wingo, Charles S

“…The collecting duct (CD) is a major renal site for the hormonal regulation of Na homeostasis and is critical for systemic arterial blood pressure control. Our…”
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The renal H+, K+-ATPases as therapeutic targets by Zies, Deborah L, Gumz, Michelle L, Wingo, Charles S, Cain, Brian D

“…The kidney is an important regulatory organ responsible for maintaining constant blood volume and composition despite wide variations in the intake of food and…”
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Effect of mineralocorticoid treatment in mice with collecting duct-specific knockout of endothelin-1 by Lynch, I Jeanette, Welch, Amanda K, Gumz, Michelle L, Kohan, Donald E, Cain, Brian D, Wingo, Charles S

“…Aldosterone increases blood pressure (BP) by stimulating sodium (Na) reabsorption within the distal nephron and collecting duct (CD). Aldosterone also…”
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