Search Results - "Cain, Anael"
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Multicellular communities are perturbed in the aging human brain and Alzheimer’s disease
Published in Nature neuroscience (01-07-2023)“…The role of different cell types and their interactions in Alzheimer’s disease (AD) is a complex and open question. Here, we pursued this question by…”
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Cellular communities reveal trajectories of brain ageing and Alzheimer’s disease
Published in Nature (London) (19-09-2024)“…Alzheimer’s disease (AD) has recently been associated with diverse cell states 1 – 11 , yet when and how these states affect the onset of AD remains unclear…”
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Cellular network perturbations point to a new microglia‐astrocyte community accelerating Alzheimer’s disease progression
Published in Alzheimer's & dementia (01-12-2022)“…Background Alzheimer’s Disease (AD) is a fatal neurodegenerative disease where abnormal accumulation of amyloid‐β and tau aggregates drive neurodegeneration…”
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Stroke genetics informs drug discovery and risk prediction across ancestries
Published in Nature (London) (01-11-2022)“…Previous genome-wide association studies (GWASs) of stroke - the second leading cause of death worldwide - were conducted predominantly in populations of…”
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