Search Results - "Caiazza, Carmen"

Induced pluripotent stem cell-derived and directly reprogrammed neurons to study neurodegenerative diseases: The impact of aging signatures by Aversano, Simona, Caiazza, Carmen, Caiazzo, Massimiliano

“…Many diseases of the central nervous system are age-associated and do not directly result from genetic mutations. These include late-onset neurodegenerative…”
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Liver Organoids: Updates on Disease Modeling and Biomedical Applications by Caiazza, Carmen, Parisi, Silvia, Caiazzo, Massimiliano

“…Liver organoids are stem cell-derived 3D structures that are generated by liver differentiation signals in the presence of a supporting extracellular matrix…”
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The Lack of STING Impairs the MHC-I Dependent Antigen Presentation and JAK/STAT Signaling in Murine Macrophages by Caiazza, Carmen, Brusco, Teresa, D'Alessio, Federica, D'Agostino, Massimo, Avagliano, Angelica, Arcucci, Alessandro, Ambrosino, Concetta, Fiume, Giuseppe, Mallardo, Massimo

“…STING is a transmembrane ER resident protein that was initially described as a regulator of innate immune response triggered by viral DNA and later found to be…”
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Effects of Long-Term Citrate Treatment in the PC3 Prostate Cancer Cell Line by Caiazza, Carmen, D'Agostino, Massimo, Passaro, Fabiana, Faicchia, Deriggio, Mallardo, Massimo, Paladino, Simona, Pierantoni, Giovanna Maria, Tramontano, Donatella

“…Acute administration of a high level of extracellular citrate displays an anti-proliferative effect on both in vitro and in vivo models. However, the long-term…”
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MicroRNA Roles in Cell Reprogramming Mechanisms by Pascale, Emilia, Caiazza, Carmen, Paladino, Martina, Parisi, Silvia, Passaro, Fabiana, Caiazzo, Massimiliano

“…Cell reprogramming is a groundbreaking technology that, in few decades, generated a new paradigm in biomedical science. To date we can use cell reprogramming…”
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Generation of a Novel Mesothelin-Targeted Oncolytic Herpes Virus and Implemented Strategies for Manufacturing by Froechlich, Guendalina, Gentile, Chiara, Infante, Luigia, Caiazza, Carmen, Pagano, Pasqualina, Scatigna, Sarah, Cotugno, Gabriella, D'Alise, Anna Morena, Lahm, Armin, Scarselli, Elisa, Nicosia, Alfredo, Mallardo, Massimo, Sasso, Emanuele, Zambrano, Nicola

“…HER2-based retargeted viruses are in advanced phases of preclinical development of breast cancer models. Mesothelin (MSLN) is a cell-surface tumor antigen…”
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Enhanced pro-apoptotic activity of rituximab through IBTK silencing in non-Hodgkin lymphoma B-cells by Vecchio, Eleonora, Marino, Rossana, Mimmi, Selena, Canale, Camilla, Caiazza, Carmen, Arcucci, Alessandro, Ruocco, Maria Rosaria, Schiavone, Marco, Santamaria, Gianluca, Palmieri, Camillo, Iaccino, Enrico, Mallardo, Massimo, Quinto, Ileana, Fiume, Giuseppe

“…Rituximab is a commonly used chemotherapeutic drug for patients with aggressive lymphomas, such as non-Hodgkin's lymphoma (NHL). Currently, the combination of…”
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Insights into Thymus Development and Viral Thymic Infections by Albano, Francesco, Vecchio, Eleonora, Renna, Maurizio, Iaccino, Enrico, Mimmi, Selena, Caiazza, Carmen, Arcucci, Alessandro, Avagliano, Angelica, Pagliara, Valentina, Donato, Giuseppe, Palmieri, Camillo, Mallardo, Massimo, Quinto, Ileana, Fiume, Giuseppe

“…T-cell development in the thymus is a complex and highly regulated process, involving a wide variety of cells and molecules which orchestrate thymocyte…”
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Exacerbation of Allergic Airway Inflammation in Mice Lacking ECTO-5'-Nucleotidase (CD73) by Caiazzo, Elisabetta, Cerqua, Ida, Riemma, Maria Antonietta, Turiello, Roberta, Ialenti, Armando, Schrader, Jurgen, Fiume, Giuseppe, Caiazza, Carmen, Roviezzo, Fiorentina, Morello, Silvana, Cicala, Carla

“…The airways are a target tissue of type I allergies and atopy is the main etiological factor of bronchial asthma. A predisposition to allergy and individual…”
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Metabolites Profiling of Melanoma Interstitial Fluids Reveals Uridine Diphosphate as Potent Immune Modulator Capable of Limiting Tumor Growth by Vecchio, Eleonora, Caiazza, Carmen, Mimmi, Selena, Avagliano, Angelica, Iaccino, Enrico, Brusco, Teresa, Nisticò, Nancy, Maisano, Domenico, Aloisio, Annamaria, Quinto, Ileana, Renna, Maurizio, Divisato, Giuseppina, Romano, Simona, Tufano, Martina, D'Agostino, Massimo, Vigliar, Elena, Iaccarino, Antonino, Mignogna, Chiara, Andreozzi, Francesco, Mannino, Gaia Chiara, Spiga, Rosangela, Stornaiuolo, Mariano, Arcucci, Alessandro, Mallardo, Massimo, Fiume, Giuseppe

“…Tumor interstitial fluid (TIF) surrounds and perfuses tumors and collects ions, metabolites, proteins, and extracellular vesicles secreted by tumor and stromal…”
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Activation of NF-κB in B cell receptor signaling through Bruton’s tyrosine kinase-dependent phosphorylation of IκB-α by Pontoriero, Marilena, Fiume, Giuseppe, Vecchio, Eleonora, de Laurentiis, Annamaria, Albano, Francesco, Iaccino, Enrico, Mimmi, Selena, Pisano, Antonio, Agosti, Valter, Giovannone, Emilia, Altobelli, Annalisa, Caiazza, Carmen, Mallardo, Massimo, Scala, Giuseppe, Quinto, Ileana

“…The antigen-mediated triggering of B cell receptor (BCR) activates the transcription factor NF-κB that regulates the expression of genes involved in B cell…”
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Integrity of the Antiviral STING-mediated DNA Sensing in Tumor Cells Is Required to Sustain the Immunotherapeutic Efficacy of Herpes Simplex Oncolytic Virus by Froechlich, Guendalina, Caiazza, Carmen, Gentile, Chiara, D’Alise, Anna Morena, De Lucia, Maria, Langone, Francesca, Leoni, Guido, Cotugno, Gabriella, Scisciola, Vittorio, Nicosia, Alfredo, Scarselli, Elisa, Mallardo, Massimo, Sasso, Emanuele, Zambrano, Nicola

“…The dichotomic contribution of cancer cell lysis and tumor immunogenicity is considered essential for effective oncovirotherapy, suggesting that the innate…”
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Thyroid Cancer and Fibroblasts by Avagliano, Angelica, Fiume, Giuseppe, Bellevicine, Claudio, Troncone, Giancarlo, Venuta, Alessandro, Acampora, Vittoria, De Lella, Sabrina, Ruocco, Maria Rosaria, Masone, Stefania, Velotti, Nunzio, Carotenuto, Pietro, Mallardo, Massimo, Caiazza, Carmen, Montagnani, Stefania, Arcucci, Alessandro

“…Thyroid cancer is the most common type of endocrine cancer, and its prevalence continue to rise. Non-metastatic thyroid cancer patients are successfully…”
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Accumulation of 8-oxodG within the human mitochondrial genome positively associates with transcription by Scala, Giovanni, Ambrosio, Susanna, Menna, Margherita, Gorini, Francesca, Caiazza, Carmen, Cooke, Marcus S, Majello, Barbara, Amente, Stefano

“…Abstract Mitochondrial DNA (mtDNA) can be subject to internal and environmental stressors that lead to oxidatively generated damage and the formation of…”
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The Roles of miR-25 and its Targeted Genes in Development of Human Cancer by Caiazza, Carmen, Mallardo, Massimo

“…microRNAs (miRNAs) are small noncoding RNAs able to suppress gene expression by targeting messenger RNAs for translational repression or, at lesser extent,…”
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