Search Results - "Cai, Zu Yun"

Estrogen receptor-independent neuroprotection via protein phosphatase preservation and attenuation of persistent extracellular signal-regulated kinase 1/2 activation by Yi, Kun Don, Cai, Zu Yun, Covey, Douglas F, Simpkins, James W

“…The mechanism of estrogen-mediated neuroprotection is not yet clear. Estrogens have a variety of modes of action, including transducing signaling events such…”
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Estrogen-like compounds for ischemic neuroprotection by Simpkins, James W, Yang, Shao-Hua, Liu, Ran, Perez, Evelyn, Cai, Zu Yun, Covey, Douglas F, Green, Pattie S

“…We have synthesized a library of estrogen analogues, including enantiomers of estradiol and A-ring substituted estrogens. These compounds have reduced or no…”
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Role of nonfeminizing estrogen analogues in neuroprotection of rat retinal ganglion cells against glutamate-induced cytotoxicity by Kumar, D. Maneesh, Perez, Evelyn, Yun Cai, Zu, Aoun, Paul, Brun-Zinkernagel, Ann-Marie, Covey, Douglas F., Simpkins, James W., Agarwal, Neeraj

“…Glaucoma is a family of eye disorders whose ultimate cause of vision loss is apoptosis of retinal ganglion cells. Although several etiologies of glaucoma…”
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Neuroprotective effects of an estratriene analog are estrogen receptor independent in vitro and in vivo by Perez, Evelyn, Liu, Ran, Yang, Shao-Hua, Cai, Zu Yun, Covey, Douglas F., Simpkins, James W.

“…Estrogens are potent neuroprotectants both in vitro and in vivo. In the present study, we compared the potency and efficacy of a non-feminizing estrogen,…”
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The estrogen receptor is not essential for all estrogen neuroprotection: new evidence from a new analog by Xia, Shuli, Cai, Zu Yun, Thio, Liu Lin, Kim-Han, Jeong Sook, Dugan, Laura L, Covey, Douglas F, Rothman, Steven M

“…We synthesized an estrogen analog, ZYC-5, lacking activity at the classical estrogen receptor and examined its neuroprotective potential against necrosis…”
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Neurosteroid analogues. 12. Potent enhancement of GABA-mediated chloride currents at GABAA receptors by ent-androgens by KATONA, Bryson W, KRISHNAN, Kathiresan, ZU YUN CAI, MANION, Brad D, BENZ, Ann, TAYLOR, Amanda, EVERS, Alex S, ZORUMSKI, Charles F, MENNERICK, Steven, COVEY, Douglas F

“…Allopregnanolone (1) and pregnanolone (2), steroids containing a 17beta-acetyl group, are potent enhancers of GABA (gamma-aminobutyric acid) action at GABAA…”
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A facile total synthesis of ent-17β-estradiol and structurally related analogues by Cai, Zu Yun, Covey, Douglas F.

“…A facile six-step synthesis (15.2% yield) of ent-17β-estradiol from readily accessible precursors is described. The preparation of analogues with 2-alkyl…”
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Photoreceptor preservation in the S334ter model of retinitis pigmentosa by a novel estradiol analog by Dykens, James A., Carroll, Amy K., Wiley, Sandra, Covey, Douglas F., Cai, Zu Yun, Zhao, Lian, Wen, Rong

“…The cytoprotective activity of MITO-4565, a novel, non-hormonal, estradiol derivative, was evaluated in the S334ter transgenic model of retinitis pigmentosa…”
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Neuroprotective effects of a novel non-receptor-binding estrogen analogue: In vitro and in vivo analysis by RAN LIU, YANG, Shao-Hua, DAY, Arthur L, SIMPKINS, James W, PEREZ, Evelyn, KUN DON YI, WU, Samuel S, EBERST, Kathleen, PROKAI, Laszlo, PROKAI-TATRAI, Katalin, ZU YUN CAI, COVEY, Douglas F

“…Although estrogens are neuroprotective, hormonal effects limit their clinical application. Estrogen analogues with neuroprotective function but lacking…”
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A facile total synthesis of ent-17beta-estradiol and structurally related analogues by Cai, Zu Yun, Covey, Douglas F

“…A facile six-step synthesis (15.2% yield) of ent-17beta-estradiol from readily accessible precursors is described. The preparation of analogues with 2-alkyl…”
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Neurosteroid analogues. 12. Potent enhancement of GABA-mediated chloride currents at GABA A receptors by ent-androgens by Katona, Bryson W., Krishnan, Kathiresan, Cai, Zu Yun, Manion, Brad D., Benz, Ann, Taylor, Amanda, Evers, Alex S., Zorumski, Charles F., Mennerick, Steven, Covey, Douglas F.

“…Allopregnanolone ( 1) and pregnanolone ( 2), steroids containing a 17β-acetyl group, are potent enhancers of GABA (γ-aminobutyric acid) action at GABA A…”
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Neuroprotective effects of estratriene analogs: structure-activity relationships and molecular optimization by Perez, Evelyn, Cai, Zu Yun, Covey, Douglas F., Simpkins, James W.

“…Estrogens are neuroprotectants against a variety of insults, both in vitro and in vivo. Many of these insults involve an oxidative stress component and…”
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Corrigendum to “Role of nonfeminizing estrogen analogues in neuroprotection of rat retinal ganglion cells against glutamate-induced cytotoxicity” [ Free Radic. Biol. Med.38:1152–1163; 2005] by Kumar, D. Maneesh, Perez, Evelyn, Cai, Zu Yun, Aoun, Paul, Brun-Zinkernagel, Ann-Marie, Covey, Douglas F., Simpkins, James W., Agarwal, Neeraj

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Mapping the locations of estradiol and potent neuroprotective analogues in phospholipid bilayers by REDOR by Cegelski, Lynette, Rice, Charles V., O'Connor, Robert D., Caruano, Amy L., Tochtrop, Gregory P., Cai, Zu Yun, Covey, Douglas F., Schaefer, Jacob

“…Estrogens are potent antioxidants and neuroprotectants. They have become the focus of drug development efforts aimed at treating and preventing neuronal damage…”
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Data fusion for fault diagnosis using multi-class Support Vector Machines by 胡中辉 蔡云泽 李远贵 许晓鸣

“…Multi-source multi-class classification methods based on multi-class Support Vector Machines and data fusion strategies are proposed in this paper. The…”
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Equilibrium of Organic Matter in Heavy Fraction for Three Long-term Experimental Field Soils in China by YIN, Yun-Feng, CAI, Zu-Cong

“…Considerable evidence that the soil organic matter （OM） level in agricultural soils will gradually over time reach an equilibrium state under certain…”
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Relationship between light and heavy fractions of organic matter for several agricultural soils in China by Yin, Yun-feng, Cai, Zu-cong, Lu, Jia-long

“…Although numerous studies about the nature and turnover of soil organic matter(SOM) in light and heavy fractions(LFOM and HFOM, respectively) have been made,…”
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Estrogen-like compounds for ischemic neuroprotection : Multimodality Imaging by SIMPKINS, James W, YANG, Shao-Hua, RAN LIU, PEREZ, Evelyn, ZU YUN CAI, COVEY, Douglas F, GREEN, Pattie S

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Neuroprotective effects of estratriene analogs : Structure-activity relationships and molecular optimization: Estrogens and Neuroprotection by PEREZ, Evelyn, ZU YUN CAI, COVEY, Douglas F, SIMPKINS, James W

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Mapping the locations of estradiol and potent neuroprotective analogues in phospholipid bilayers by REDOR: Estrogens and Neuroprotection by CEGELSKI, Lynette, RICE, Charles V, O'CONNOR, Robert D, CARUANO, Amy L, TOCHTROP, Gregory P, ZU YUN CAI, COVEY, Douglas F, SCHAEFER, Jacob

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