Search Results - "Cai, Yanxing"
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AIM2 Facilitates the Apoptotic DNA-induced Systemic Lupus Erythematosus via Arbitrating Macrophage Functional Maturation
Published in Journal of clinical immunology (01-07-2013)“…Purpose Lupus nephritis, a major cause of morbidity in patients with systemic lupus erythematosus (SLE), is generally thought to be induced by…”
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25-Hydroxycholesterol-Conjugated EK1 Peptide with Potent and Broad-Spectrum Inhibitory Activity against SARS-CoV-2, Its Variants of Concern, and Other Human Coronaviruses
Published in International journal of molecular sciences (01-11-2021)“…The COVID-19 pandemic caused by SARS-CoV-2 infection poses a serious threat to global public health and the economy. The enzymatic product of cholesterol…”
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A bivalent protein targeting glycans and HR1 domain in spike protein potently inhibited infection of SARS-CoV-2 and other human coronaviruses
Published in Cell & bioscience (08-07-2021)“…Abstract Background Our previous studies have shown that combining the antiviral lectin GRFT and the pan-CoV fusion inhibitory peptide EK1 results in highly…”
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Inhibition of influenza A virus and SARS-CoV-2 infection or co-infection by griffithsin and griffithsin-based bivalent entry inhibitor
Published in mBio (08-05-2024)“…Outbreaks of acute respiratory viral diseases, such as influenza and COVID-19 caused by influenza A virus (IAV) and SARS-CoV-2, pose a serious threat to global…”
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Anti-SARS-CoV-2 IgY Isolated from Egg Yolks of Hens Immunized with Inactivated SARS-CoV-2 for Immunoprophylaxis of COVID-19
Published in Virologica Sinica (01-10-2021)Get full text
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Mannose-binding lectin blunts macrophage polarization and ameliorates lupus nephritis
Published in PloS one (23-04-2013)“…Deficiency in clearance of self nuclear antigens, including DNA, is the hallmark of systemic lupus erythematosus (SLE), a chronic autoimmnue disease…”
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A highly potent and stable pan-coronavirus fusion inhibitor as a candidate prophylactic and therapeutic for COVID-19 and other coronavirus diseases
Published in Acta pharmaceutica Sinica. B (01-04-2022)“…The development of broad-spectrum antivirals against human coronaviruses (HCoVs) is critical to combat the current coronavirus disease 2019 (COVID-19) pandemic…”
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Review on key technologies and typical applications of multi-station integrated energy systems
Published in Global Energy Interconnection (01-06-2022)“…To realize the low-carbon development of power systems, digital transformation, and power marketization reform, the substation, data center, energy storage,…”
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An algal lectin griffithsin inhibits Hantaan virus infection in vitro and in vivo
Published in Frontiers in cellular and infection microbiology (12-12-2022)“…Hantaan virus (HTNV) is the etiological pathogen of hemorrhagic fever with renal syndrome in East Asia. There are currently no effective therapeutics approved…”
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Optimal construction method and demonstration application of multi-in-one station grounding system
Published in Global Energy Interconnection (01-10-2021)“…Mutual influence may be driven by different models and operating mechanisms of grounding systems in multi-in- one substations. Even equipment damage and…”
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Candida albicans biofilms: antifungal resistance, immune evasion, and emerging therapeutic strategies
Published in International journal of antimicrobial agents (01-11-2022)“…•Candida albicans biofilm-associated infections are a huge clinical challenge.•C. albicans biofilm is highly resistant to antifungal drugs and the host immune…”
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DNA-dependent Activator of Interferon-regulatory Factors (DAI) Promotes Lupus Nephritis by Activating the Calcium Pathway
Published in The Journal of biological chemistry (10-05-2013)“…DNA-dependent activator of interferon-regulatory factors (DAI) functions as a cytoplasmic DNA sensor that activates the innate immune system. We previously…”
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Lipopeptide-based pan-CoV fusion inhibitors potently inhibit HIV-1 infection
Published in Microbes and infection (01-09-2021)Get full text
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Clinical characteristics of tracheobronchomalacia complicated with pulmonary infection in children and the significance of electronic fiberoptic bronchoscopy in diagnosis and treatment
Published in Xīn yīxué (01-12-2023)“…Objective To analyze the clinical features of children with tracheobronchomalacia (TBM) complicated with pulmonary infection,and to explore the significance of…”
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Digital Twin and Its Application in Power System
Published in 2020 5th International Conference on Power and Renewable Energy (ICPRE) (12-09-2020)“…This paper introduces the digital twinning technology, which integrates multi-disciplinary, multi-physical, multi-scale and multi-probability simulation…”
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Mannose-Binding Lectin Blunts Macrophage Polarization and Ameliorates Lupus Nephritis. e62465
Published in PloS one (01-04-2013)“…Background Deficiency in clearance of self nuclear antigens, including DNA, is the hallmark of systemic lupus erythematosus (SLE), a chronic autoimmnue disease…”
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C-reactive protein functions as a negative regulator of macrophage activation induced by apoptotic DNA
Published in Protein & cell (01-08-2011)“…C-reactive protein (CRP), an acute-phase protein with an ability to bind to nuclear antigen, has been reported to regulate cytokine secretion and modulate…”
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Research progress regarding autophagy in inflammatory diseases
Published in Zhonghua wei zhong bing ji jiu yi xue (01-06-2015)Get more information
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