Search Results - "Cai, Xiujun"

Laparoscopic liver resection: the current status and the future by Cai, Xiujun

“…Dramatic progresses had been made in the operation in the past 26 years. Procedure was extended to major liver resection, isolated resection of caudate lobe,…”
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The microenvironmental and metabolic aspects of sorafenib resistance in hepatocellular carcinoma by Xia, Shunjie, Pan, Yu, Liang, Yuelong, Xu, Junjie, Cai, Xiujun

“…In most cases, sorafenib-resistant HCC cells exhibit significant mesenchymal phenotype and stemness features. In this context, tumor cells might undergo cell…”
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Targeting mutant p53 for cancer therapy: direct and indirect strategies by Hu, Jiahao, Cao, Jiasheng, Topatana, Win, Juengpanich, Sarun, Li, Shijie, Zhang, Bin, Shen, Jiliang, Cai, Liuxin, Cai, Xiujun, Chen, Mingyu

“…Abstract TP53 is a critical tumor-suppressor gene that is mutated in more than half of all human cancers. Mutations in TP53 not only impair its antitumor…”
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CircRNA-SORE mediates sorafenib resistance in hepatocellular carcinoma by stabilizing YBX1 by Xu, Junjie, Ji, Lin, Liang, Yuelong, Wan, Zhe, Zheng, Wei, Song, Xiaomin, Gorshkov, Kirill, Sun, Qiming, Lin, Hui, Zheng, Xueyong, Chen, Jiang, Jin, Ren-an, Liang, Xiao, Cai, Xiujun

“…Sorafenib is the first-line chemotherapeutic therapy for advanced hepatocellular carcinoma (HCC). However, sorafenib resistance significantly limits its…”
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Circular RNAs: characteristics, biogenesis, mechanisms and functions in liver cancer by Shen, Hao, Liu, Boqiang, Xu, Junjie, Zhang, Bin, Wang, Yifan, Shi, Liang, Cai, Xiujun

“…Hepatocellular carcinoma (HCC) is one of the most common malignancies globally. Despite aggressive and multimodal treatment regimens, the overall survival of…”
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A Ring in the Liver by Xu, Junjie, Liang, Xiao, Cai, Xiujun

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Classification and mutation prediction based on histopathology H&E images in liver cancer using deep learning by Chen, Mingyu, Zhang, Bin, Topatana, Win, Cao, Jiasheng, Zhu, Hepan, Juengpanich, Sarun, Mao, Qijiang, Yu, Hong, Cai, Xiujun

“…Hepatocellular carcinoma (HCC) is the most common subtype of liver cancer, and assessing its histopathological grade requires visual inspection by an…”
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Chk1-induced CCNB1 overexpression promotes cell proliferation and tumor growth in human colorectal cancer by Fang, Yifeng, Yu, Hong, Liang, Xiao, Xu, Junfen, Cai, Xiujun

“…The high morbidity and mortality of colorectal cancer pose a significant public health problem worldwide. Here we assessed the pro-cancer efficacy and…”
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Human mesenchymal stem cells promote tumor growth via MAPK pathway and metastasis by epithelial mesenchymal transition and integrin α5 in hepatocellular carcinoma by Chen, Jiang, Ji, Tong, Wu, Di, Jiang, Shi, Zhao, Jie, Lin, Hui, Cai, Xiujun

“…Mesenchymal stem cells (MSCs) appear to be a potential vehicle for anticancer drugs due to their excellent tumor tropism ability. However, the interactions…”
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Cancer-derived exosomes as novel biomarkers in metastatic gastrointestinal cancer by Zhong, Danyang, Wang, Ziyuan, Ye, Zhichao, Wang, Yifan, Cai, Xiujun

“…Gastrointestinal cancer (GIC) is the most prevalent and highly metastatic malignant tumor and has a significant impact on mortality rates. Nevertheless, the…”
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FeS@BSA Nanoclusters to Enable H2S‐Amplified ROS‐Based Therapy with MRI Guidance by Xie, Congkun, Cen, Dong, Ren, Zhaohui, Wang, Yifan, Wu, Yongjun, Li, Xiang, Han, Gaorong, Cai, Xiujun

“…Therapeutic systems to induce reactive oxygen species (ROS) have received tremendous success in the research of tumor theranostics, but suffered daunting…”
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Isoalantolactone suppresses gallbladder cancer progression via inhibiting the ERK signalling pathway by Lv, Xingyu, Lin, Yuqi, Zhu, Xi, Cai, Xiujun

“…Gallbladder cancer (GBC) is the most common malignant tumour of the biliary tract. Isoalantolactone (IAL), an active sesquiterpene lactone compound isolated…”
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IRF3 prevents colorectal tumorigenesis via inhibiting the nuclear translocation of β-catenin by Tian, Miao, Wang, Xiumei, Sun, Jihong, Lin, Wenlong, Chen, Lumin, Liu, Shengduo, Wu, Ximei, Shi, Liyun, Xu, Pinglong, Cai, Xiujun, Wang, Xiaojian

“…Occurrence of Colorectal cancer (CRC) is relevant with gut microbiota. However, role of IRF3, a key signaling mediator in innate immune sensing, has been…”
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UBQLN1 mediates sorafenib resistance through regulating mitochondrial biogenesis and ROS homeostasis by targeting PGC1β in hepatocellular carcinoma by Xu, Junjie, Ji, Lin, Ruan, Yeling, Wan, Zhe, Lin, Zhongjie, Xia, Shunjie, Tao, Liye, Zheng, Junhao, Cai, Liuxin, Wang, Yifan, Liang, Xiao, Cai, Xiujun

“…The treatment for hepatocellular carcinoma (HCC) is promising in recent years, but still facing critical challenges. The first targeted therapy, sorafenib,…”
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Advances in synthetic lethality for cancer therapy: cellular mechanism and clinical translation by Topatana, Win, Juengpanich, Sarun, Li, Shijie, Cao, Jiasheng, Hu, Jiahao, Lee, Jiyoung, Suliyanto, Kenneth, Ma, Diana, Zhang, Bin, Chen, Mingyu, Cai, Xiujun

“…Synthetic lethality is a lethal phenomenon in which the occurrence of a single genetic event is tolerable for cell survival, whereas the co-occurrence of…”
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Comparative efficacy of microwave ablation and radiofrequency ablation for treating metastatic liver cancer: a systematic review and meta-analysis by Li, Zheng, Yan, Tingting, Cai, Xiujun

“…Objective This study aims at evaluating and juxtaposing the efficacy of radiofrequency ablation (RFA) and microwave ablation (MWA) for hepatic metastases…”
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Founder cells for hepatocytes during liver regeneration: from identification to application by Wei, Saisai, Tang, Jiacheng, Cai, Xiujun

“…Liver regeneration (LR) capacity in vertebrates developed through natural selection over a hundred million years of evolution. To maintain homeostasis or…”
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ACLS4 could be a potential therapeutic target for severe acute pancreatitis by Guo, Feng, Lu, Yunkun, Du, Lijun, Guo, Xiuliu, Xie, Jinyan, Cai, Xiujun

“…Acute pancreatitis (AP) is currently among the most prevalent digestive diseases. The pathogenesis of AP remains elusive, and there is no specific treatment…”
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miR-486-3p mediates hepatocellular carcinoma sorafenib resistance by targeting FGFR4 and EGFR by Ji, Lin, Lin, Zhongjie, Wan, Zhe, Xia, Shunjie, Jiang, Shi, Cen, Dong, Cai, Liuxin, Xu, Junjie, Cai, Xiujun

“…HCC is a common malignancy worldwide and surgery or reginal treatments are deemed insufficient for advanced-stage disease. Sorafenib is an inhibitor of many…”
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Androgen receptor roles in hepatocellular carcinoma, fatty liver, cirrhosis and hepatitis by Ma, Wen-Lung, Lai, Hsueh-Chou, Yeh, Shuyuan, Cai, Xiujun, Chang, Chawnshang

“…Androgen/androgen receptor (AR) signaling plays important roles in normal liver function and in progression of liver diseases. In studies of noncancerous liver…”
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