Search Results - "Cai, Xingshan"
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The compound TB47 is highly bactericidal against Mycobacterium ulcerans in a Buruli ulcer mouse model
Published in Nature communications (31-01-2019)“…Buruli ulcer (BU) is an emerging infectious disease that causes disfiguring skin ulcers. The causative agent, Mycobacterium ulcerans , secretes toxin called…”
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Epidemiology of pulmonary disease due to nontuberculous mycobacteria in Southern China, 2013-2016
Published in BMC pulmonary medicine (09-11-2018)“…Pulmonary nontuberculous mycobacteria (NTM) disease is of increasing public health concern in China. Information is limited regarding risk factors associated…”
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Airway microecology in rifampicin-resistant and rifampicin-sensitive pulmonary tuberculosis patients
Published in BMC microbiology (29-11-2022)“…Pulmonary tuberculosis is a chronic infectious disease of the respiratory system. It is still one of the leading causes of death from a single infectious…”
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Role of pncA and rpsA Gene Sequencing in Detection of Pyrazinamide Resistance in Mycobacterium tuberculosis Isolates from Southern China
Published in Journal of Clinical Microbiology (01-01-2014)“…Classifications Services JCM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Dynamic changes of respiratory microbiota associated with treatment outcome in drug-sensitive and drug-resistant pulmonary tuberculosis
Published in Annals of clinical microbiology and antimicrobials (09-09-2024)“…Respiratory microbiota is closely related to tuberculosis (TB) initiation and progression. However, the dynamic changes of respiratory microbiota during…”
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Pyrazinoic Acid Inhibits a Bifunctional Enzyme in Mycobacterium tuberculosis
Published in Antimicrobial agents and chemotherapy (01-07-2017)“…Pyrazinamide (PZA), an indispensable component of modern tuberculosis treatment, acts as a key sterilizing drug. While the mechanism of activation of this…”
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The Beginning of the rpoB Gene in Addition to the Rifampin Resistance Determination Region Might Be Needed for Identifying Rifampin/Rifabutin Cross-Resistance in Multidrug-Resistant Mycobacterium tuberculosis Isolates from Southern China
Published in Journal of Clinical Microbiology (01-01-2012)“…OA Article Usage Stats Services JCM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+…”
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Evaluation of the MTBDRplus 2.0 assay for the detection of multidrug resistance among persons with presumptive pulmonary TB in China
Published in Scientific reports (13-06-2017)“…We have conducted a multicenter study of the diagnostic accuracy of the MTBDR plus 2.0 assay in compared with conventional and molecular reference standard in…”
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Comparative Analysis of Whole-Genome and Methylome Profiles of a Smooth and a Rough Mycobacterium abscessus Clinical Strain
Published in G3 : genes - genomes - genetics (01-01-2020)“…is a fast growing species mainly causing skin and respiratory infections in human. is resistant to numerous drugs, which is a major challenge for the…”
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Prevalence and molecular characterization of amikacin resistance among Mycobacterium tuberculosis clinical isolates from southern China
Published in Journal of global antimicrobial resistance. (01-09-2020)“…•Amikacin is only considered for multidrug-resistant tuberculosis (MDR-TB) treatment when a short MDR-TB regimen is designed.•The rrs mutations were found in…”
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Solar sailing trajectory optimization with planetary gravity assist
Published in Science China. Physics, mechanics & astronomy (01-01-2015)“…Significant propellant mass saving can be obtained with the use of complex multiple intermediate flyby maneuvers for conventional propulsion systems, and trip…”
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Rapid Identification of Clinically Relevant Mycobacterium Species by Multicolor Melting Curve Analysis
Published in Journal of clinical microbiology (01-01-2019)“…The sustained increase in the incidence of nontuberculous mycobacterial (NTM) infection and the difficulty in distinguishing these infections from tuberculosis…”
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Rapid diagnosis of MDR and XDR tuberculosis with the MeltPro TB assay in China
Published in Scientific reports (06-05-2016)“…New diagnostic methods have provided a promising solution for rapid and reliable detection of drug-resistant TB strains. The aim of this study was to evaluate…”
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Assessment of Clofazimine and TB47 Combination Activity against Mycobacterium abscessus Using a Bioluminescent Approach
Published in Antimicrobial agents and chemotherapy (21-02-2020)“…is intrinsically resistant to most antimicrobial agents. The emerging infections caused by and the lack of effective treatment call for rapid attention. Here,…”
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Role of the Cys154Arg Substitution in Ribosomal Protein L3 in Oxazolidinone Resistance in Mycobacterium tuberculosis
Published in Antimicrobial agents and chemotherapy (01-05-2016)“…We expressed the wild-type rplC and mutated rplC (Cys154Arg) genes, respectively, in Mycobacterium tuberculosis H37Ra and H37Rv in an attempt to delineate the…”
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Phenotypic and Genotypic Characterization of Streptomycin-Resistant Multidrug-Resistant Mycobacterium tuberculosis Clinical Isolates in Southern China
Published in Microbial drug resistance (Larchmont, N.Y.) (01-07-2020)“…Streptomycin (STR) is the first antibiotic used in the treatment of tuberculosis (TB) and the earliest antituberculosis drug with acquired resistance developed…”
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Structural and Biochemical Characterization of the Cognate and Heterologous Interactions of the MazEF-mt9 TA System
Published in ACS infectious diseases (09-08-2019)“…Toxin–antitoxin (TA) modules widely exist in bacteria, and their activities are associated with the persister phenotype of the pathogen Mycobacterium…”
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Correction to Structural and Biochemical Characterization of the Cognate and Heterologous Interactions of the MazEF-mt9 TA System
Published in ACS infectious diseases (11-09-2020)Get full text
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The therapeutic effect of regimens containing isoniazid and rifampicin for pulmonary tuberculosis with single isoniazid or rifampicin resistance
Published in Zhonghua jiehe he huxi zazhi (01-12-2014)“…To study regimens containing isoniazid and rifampicin for the treatment of pulmonary tuberculosis with isoniazid or rifampicin resistance. Eighty patients with…”
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