Search Results - "Cai, Xianyi"

Nav1.7 as a chondrocyte regulator and therapeutic target for osteoarthritis by Fu, Wenyu, Vasylyev, Dmytro, Bi, Yufei, Zhang, Mingshuang, Sun, Guodong, Khleborodova, Asya, Huang, Guiwu, Zhao, Libo, Zhou, Renpeng, Li, Yonggang, Liu, Shujun, Cai, Xianyi, He, Wenjun, Cui, Min, Zhao, Xiangli, Hettinghouse, Aubryanna, Good, Julia, Kim, Ellen, Strauss, Eric, Leucht, Philipp, Schwarzkopf, Ran, Guo, Edward X., Samuels, Jonathan, Hu, Wenhuo, Attur, Mukundan, Waxman, Stephen G., Liu, Chuan-ju

“…Osteoarthritis (OA) is the most common joint disease. Currently there are no effective methods that simultaneously prevent joint degeneration and reduce pain 1…”
Get full text

CircHGF suppressed cell proliferation and osteogenic differentiation of BMSCs in ONFH via inhibiting miR-25-3p binding to SMAD7 by Feng, Xiaobo, Xiang, Qian, Jia, Jie, Guo, Tingting, Liao, Zhiwei, Yang, Shuhua, Cai, Xianyi, Liu, Xianzhe

“…Steroid-induced osteonecrosis of the femoral head (ONFH) is a common and devastating bone disorder, which often results in progressive collapse of the femoral…”
Get full text

Tunneling Nanotube-Mediated Mitochondrial Transfer Rescues Nucleus Pulposus Cells from Mitochondrial Dysfunction and Apoptosis by Yang, Fan, Zhang, Yanbin, Liu, Sheng, Xiao, Jiheng, He, Yuxin, Shao, Zengwu, Zhang, Yuhui, Cai, Xianyi, Xiong, Liming

“…Stem cell-based therapy has been indicated to be beneficial for intervertebral disc regeneration. However, the underlying mechanisms have not been fully…”
Get full text

ROS-mediated lysosomal membrane permeabilization is involved in bupivacaine-induced death of rabbit intervertebral disc cells by Cai, Xianyi, Liu, Yunlu, Hu, Yiqiang, Liu, Xianzhe, Jiang, Hongyan, Yang, Shuhua, Shao, Zengwu, Xia, Yun, Xiong, Liming

“…Bupivacaine is frequently administered for diagnosing and controlling spine-related pain in interventional spine procedures. However, the potential cytotoxic…”
Get full text

Regulated cell death: Implications for intervertebral disc degeneration and therapy by Yang, Fan, Liu, Weijian, Huang, Yongcan, Yang, Shuhua, Shao, Zengwu, Cai, Xianyi, Xiong, Liming

“…As a controllable biological process, regulated cell death (RCD) extensively participates in cellular homeostasis, organismal development, and the pathogenesis…”
Get full text

Pioglitazone Protects Compression-Mediated Apoptosis in Nucleus Pulposus Mesenchymal Stem Cells by Suppressing Oxidative Stress by Zhang, Yanbin, Shao, Zengwu, Cai, Xianyi, Xiong, Liming, Ma, Kaige, Ding, Fan, Wu, Yongchao, Liu, Guohui, Liu, Yunlu, Shen, Min, Huang, Liang, Hu, Yiqiang, Wang, Wentian

“…Excessive compression, the main cause of intervertebral disc (IVD) degeneration, affected endogenous repair of the intervertebral disc. Pioglitazone (PGZ) is…”
Get full text

Current Progress in the Endogenous Repair of Intervertebral Disk Degeneration Based on Progenitor Cells by Zhang, Yanbin, Hu, Yiqiang, Wang, Wentian, Guo, Zijun, Yang, Fan, Cai, Xianyi, Xiong, Liming

“…Intervertebral disk (IVD) degeneration is one of the most common musculoskeletal disease. Current clinical treatment paradigms for IVD degeneration cannot…”
Get full text

Traumatic brain injury stimulates sympathetic tone-mediated bone marrow myelopoiesis to favor fracture healing by Liu, Weijian, Chen, Wei, Xie, Mao, Chen, Chao, Shao, Zengwu, Zhang, Yiran, Zhao, Haiyue, Song, Qingcheng, Hu, Hongzhi, Xing, Xin, Cai, Xianyi, Deng, Xiangtian, Li, Xinyan, Wang, Peng, Liu, Guohui, Xiong, Liming, Lv, Xiao, Zhang, Yingze

“…Traumatic brain injury (TBI) accelerates fracture healing, but the underlying mechanism remains largely unknown. Accumulating evidence indicates that the…”
Get full text

The Effect of a PEEK Material‐Based External Fixator in the Treatment of Distal Radius Fractures with Non‐Transarticular External Fixation by Xie, Mao, Cao, Yinghao, Cai, Xianyi, Shao, Zengwu, Nie, Ke, Xiong, Liming

“…Objective To explore the effect of a PEEK material‐based external fixator in the treatment of distal radius fractures with non‐transarticular external…”
Get full text

Dioscin inhibits the growth of human osteosarcoma by inducing G2/M‐phase arrest, apoptosis, and GSDME‐dependent cell death in vitro and in vivo by Ding, Qiuyue, Zhang, Wenda, Cheng, Cheng, Mo, Fengbo, Chen, Lei, Peng, Guangfu, Cai, Xianyi, Wang, Jinglong, Yang, Shuhua, Liu, Xianzhe

“…Pyroptosis is a form of programmed cell death (PCD) that plays a vital role in immunity and diseases. Although it was recently reported that chemotherapy drugs…”
Get full text

Long noncoding RNA MALAT1 as a potential therapeutic target in osteosarcoma by Cai, Xianyi, Liu, Yunlu, Yang, Wen, Xia, Yun, Yang, Cao, Yang, Shuhua, Liu, Xianzhe

“…ABSTRACT Recent studies have revealed that long noncoding RNA metastasis‐associated lung adenocarcinoma transcript 1 (MALAT1) plays an important role in the…”
Get full text

LncRNA CRNDE is activated by SP1 and promotes osteosarcoma proliferation, invasion, and epithelial‐mesenchymal transition via Wnt/β‐catenin signaling pathway by Ding, Qiuyue, Mo, Fengbo, Cai, Xianyi, Zhang, Wenda, Wang, Jinglong, Yang, Shuhua, Liu, Xianzhe

“…Long noncoding RNAs (lncRNAs) were identified as a vital part in the development and progression of cancer in recent years. Colorectal neoplasia differentially…”
Get full text

Mitochondrial Pathway Is Involved in Advanced Glycation End Products-Induced Apoptosis of Rabbit Annulus Fibrosus Cells by Hu, Yiqiang, Shao, Zengwu, Cai, Xianyi, Liu, Yunlu, Shen, Min, Yao, Yingtao, Yuan, Tian, Wang, Wentian, Ding, Fan, Xiong, Liming

“…STUDY DESIGN.Experimental study. OBJECTIVE.The purposes of this study were to evaluate whether advanced glycation end-products (AGEs) induce annulus fibrosus…”
Get full text

Association Between Lumbar Disc Degeneration and Propionibacterium acnes Infection: Clinical Research and Preliminary Exploration of Animal Experiment by Li, Bo, Dong, Zhe, Wu, Yongchao, Zeng, Ji, Zheng, Qixin, Xiao, Baojun, Cai, Xianyi, Xiao, Zhiyong

“…Clinical research and animal experiment. To investigate whether lumbar disc degeneration is associated with Propionibacterium acnes (P acnes) infection. The…”
Get full text

Digoxin targets low density lipoprotein receptor-related protein 4 and protects against osteoarthritis by Wang, Kai-di, Ding, Xiang, Jiang, Nan, Zeng, Chao, Wu, Jing, Cai, Xian-Yi, Hettinghouse, Aubryanna, Khleborodova, Asya, Lei, Zi-Ning, Chen, Zhe-Sheng, Lei, Guang-Hua, Liu, Chuan-Ju

“…Dysregulated chondrocyte metabolism is closely associated with the pathogenesis of osteoarthritis (OA). Suppressing chondrocyte catabolism to restore cartilage…”
Get more information

RhoA/ROCK pathway inhibition by fasudil suppresses the vasculogenic mimicry of U2OS osteosarcoma cells in vitro by Xia, Yun, Cai, Xianyi, Fan, Jiquan, Zhang, Liling, Li, Zhenyu, Ren, Jinghua, Wu, Gang, Zhu, Fang

“…GTPase RhoA and its downstream Rho-associated coiled-coil-containing protein kinases (ROCKs) are frequently overexpressed in human cancers. Inhibition of the…”
Get full text

Establishment and characterization of a novel osteosarcoma cell line: CHOS by Liu, Yunlu, Feng, Xiaobo, Zhang, Yukun, Jiang, Hongyan, Cai, Xianyi, Yan, Xinxin, Huang, Zengfa, Mo, Fengbo, Yang, Wen, Yang, Cao, Yang, Shuhua, Liu, Xianzhe

“…ABSTRACT Osteosarcoma has a well‐recognized bimodal distribution, with the first peak in adolescence and another in the elderly age‐group. The elderly patients…”
Get full text

The Influence of Tetracycline Inducible Targeting Rat PPARγ Gene Silencing on the Osteogenic and Adipogenic Differentiation of Bone Marrow Stromal Cells by Feng, Xiaobo, Liu, Xianzhe, Cai, Xianyi, Lin, Tao, Xu, Weihua, Yang, Cao, Liu, Yongwei, Yang, Shuhua, Fu, Dehao

“…Peroxisome proliferator-activated receptor γ (PPARγ) has been considered as the master regulator for adipogenesis of bone marrow stromal cells (BMSCs)…”
Get more information

Na v 1.7 as a chondrocyte regulator and therapeutic target for osteoarthritis by Fu, Wenyu, Vasylyev, Dmytro, Bi, Yufei, Zhang, Mingshuang, Sun, Guodong, Khleborodova, Asya, Huang, Guiwu, Zhao, Libo, Zhou, Renpeng, Li, Yonggang, Liu, Shujun, Cai, Xianyi, He, Wenjun, Cui, Min, Zhao, Xiangli, Hettinghouse, Aubryanna, Good, Julia, Kim, Ellen, Strauss, Eric, Leucht, Philipp, Schwarzkopf, Ran, Guo, Edward X, Samuels, Jonathan, Hu, Wenhuo, Attur, Mukundan, Waxman, Stephen G, Liu, Chuan-Ju

“…Osteoarthritis (OA) is the most common joint disease. Currently there are no effective methods that simultaneously prevent joint degeneration and reduce pain …”
Get full text