Search Results - "Cai, Tianyu"
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Targeting CD123 in blastic plasmacytoid dendritic cell neoplasm using allogeneic anti-CD123 CAR T cells
Published in Nature communications (28-04-2022)“…Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare hematologic malignancy with poor outcomes with conventional therapy. Nearly 100% of BPDCNs…”
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Calunduloside E inhibits HepG2 cell proliferation and migration via p38/JNK-HMGB1 signalling axis
Published in Journal of pharmacological sciences (01-09-2021)“…High-mobility group box 1 (HMGB1), a highly conserved chromosome protein, is considered as a potential therapeutic target and novel biomarker because of its…”
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Genome-Wide Identification and Characterization of Calcium-Dependent Protein Kinase ( CDPK ) and CDPK-Related Kinase ( CRK ) Gene Families in Medicago truncatula
Published in International journal of molecular sciences (21-01-2021)“…Calcium-dependent protein kinase (CDPK or CPK) and CDPK-related kinase (CRK) play an important role in plant growth, development, and adaptation to…”
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Blastic Plasmacytoid Dendritic Cell Neoplasm Is Dependent on BCL2 and Sensitive to Venetoclax
Published in Cancer discovery (01-02-2017)“…Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is an aggressive hematologic malignancy with dismal outcomes for which no standard therapy exists. We…”
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Long-term outcomes of acellular dermal matrix graft (ADMG) carrying with autologous urothelial cells in the urethroplasty: Case reports
Published in Asian journal of surgery (01-09-2023)Get full text
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Zoonotic Threat of G4 Genotype Eurasian Avian-Like Swine Influenza A(H1N1) Viruses, China, 2020
Published in Emerging infectious diseases (01-08-2022)“…We investigated genetic and biologic characteristics of 2 Eurasian avian-like H1N1 swine influenza viruses from pigs in China that belong to the predominant G4…”
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Balloon dilation for the treatment of male urethral strictures: a systematic review and meta-analysis
Published in BMJ open (06-02-2024)“…ObjectiveThe use of minimally invasive endoluminal treatment for urethral strictures has been a subject for debate for several decades. The aim of this study…”
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Aloin Inhibits the Proliferation and Migration of Gastric Cancer Cells by Regulating NOX2-ROS-Mediated Pro-Survival Signal Pathways
Published in Drug design, development and therapy (01-01-2020)“…Aloin has been reported to have many pharmacological effects including anti-inflammatory, anti-oxidant and anti-tumour activities. However, the precise…”
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High mobility group box 1 regulates gastric cancer cell proliferation and migration via RAGE-mTOR/ERK feedback loop
Published in Journal of Cancer (01-01-2021)“…Gastric cancer (GC) is a common malignancy tumour in China. Despite various therapeutic approaches to improve the survival rate of GC patients, the…”
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Investigation on the Electrochemical Deposition of Nanocrystalline Zinc with Cationic Polyacrylamide (CPAM)-ZnSO4 Electrolyte
Published in Micromachines (Basel) (17-09-2021)“…The electrochemical deposition of nanocrystalline zinc has high potential to deposit zinc coatings, which have improved wear and corrosion properties compared…”
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Adipose stem cells in tissue regeneration and repair: from bench to bedside
Published in Regenerative therapy (01-12-2023)“…ADSCs are a large number of mesenchymal stem cells in Adipose tissue, which can be applied to tissue engineering. ADSCs have the potential of multi-directional…”
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Exogenous mitochondrial transfer and endogenous mitochondrial fission facilitate AML resistance to OxPhos inhibition
Published in Blood advances (26-10-2021)“…Acute myeloid leukemia (AML) cells are highly dependent on oxidative phosphorylation (OxPhos) for survival, and they continually adapt to fluctuations in…”
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Superior efficacy of cotreatment with BET protein inhibitor and BCL2 or MCL1 inhibitor against AML blast progenitor cells
Published in Blood cancer journal (New York) (15-01-2019)“…First-generation bromodomain extra-terminal protein (BETP) inhibitors (BETi) (e.g., OTX015) that disrupt binding of BETP BRD4 to chromatin transcriptionally…”
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Inhibition of mTORC1/C2 signaling improves anti-leukemia efficacy of JAK/STAT blockade in CRLF2 rearranged and/or JAK driven Philadelphia chromosome-like acute B-cell lymphoblastic leukemia
Published in Oncotarget (30-01-2018)“…Patients with cytokine receptor-like factor 2 rearranged ( -re) subgroup Philadelphia chromosome-like B-cell acute lymphoblastic leukemia (Ph-like B-ALL) have…”
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A 10-m annual grazing intensity dataset in 2015–2021 for the largest temperate meadow steppe in China
Published in Scientific data (10-02-2024)“…Mapping grazing intensity (GI) using satellites is crucial for developing adaptive utilization strategies according to grassland conditions. Here we developed…”
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Overexpression of CD200 is a stem cell-specific mechanism of immune evasion in AML
Published in Journal for immunotherapy of cancer (01-07-2021)“…BackgroundAcute myeloid leukemia (AML) stem cells (LSCs) are capable of surviving current standard chemotherapy and are the likely source of deadly, relapsed…”
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The molecular mechanisms of Aloin induce gastric cancer cells apoptosis by targeting High Mobility Group Box 1
Published in Drug design, development and therapy (01-04-2019)“…Aloin (ALO), a bioactive ingredient extracted from aloe vera, has anti-tumor effects. High Mobility Group Box 1 (HMGB1), a highly conserved nuclear DNA-binding…”
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Phylogenetic tracing and biological characterization of a novel clade 2.3.2.1 reassortant of H5N6 subtype avian influenza virus in China
Published in Transboundary and emerging diseases (01-03-2021)“…In recent years in China, clade 2.3.4.4 H5N6 plus clade 2.3.2.1 H5N1 subtype highly pathogenic avian influenza (HPAI) viruses have gradually become endemic in…”
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BZYX, a novel acetylcholinesterase inhibitor, significantly improved chemicals-induced learning and memory impairments on rodents and protected PC12 cells from apoptosis induced by hydrogen peroxide
Published in European journal of pharmacology (24-06-2009)“…BZYX was designed as a dual-binding-site acetylcholinesterase (AChE) inhibitor and selected from series of indanone derivatives. The present study was designed…”
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High-precision projection moiré measurement method for the large depth of field with significant distortion
Published in Measurement : journal of the International Measurement Confederation (15-02-2023)“…The projection moiré method is a high-precision optical topography measurement method. Because the reception system has the complex characteristic of two-stage…”
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