Search Results - "Cai, Sidong"
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1
The poly(ADP-ribosyl)ation of BRD4 mediated by PARP1 promoted pathological cardiac hypertrophy
Published in Acta pharmaceutica Sinica. B (01-05-2021)“…The bromodomain and extraterminal (BET) family member BRD4 is pivotal in the pathogenesis of cardiac hypertrophy. BRD4 induces hypertrophic gene expression by…”
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Journal Article -
2
PRMT5 Prevents Cardiomyocyte Hypertrophy via Symmetric Dimethylating HoxA9 and Repressing HoxA9 Expression
Published in Frontiers in pharmacology (10-12-2020)“…The present study reveals a link between protein arginine methyltransferase 5 (PRMT5) and Homebox A9 (HoxA9) in the regulation of cardiomyocyte hypertrophy. In…”
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Journal Article -
3
PKCζ interacts with STAT3 and promotes its activation in cardiomyocyte hypertrophy
Published in Journal of pharmacological sciences (01-09-2016)“…This study was aimed to investigate the crosstalk between protein kinase C ζ (PKCζ) and signal transducer and activator of transcription 3 (STAT3) in…”
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Journal Article -
4
Histone Demethylase JMJD3 Mediated Doxorubicin-Induced Cardiomyopathy by Suppressing SESN2 Expression
Published in Frontiers in cell and developmental biology (29-09-2020)“…Jumonji domain-containing 3 (JMJD3) protein, a histone demethylase protein, specifically catalyzes the demethylation of H3K27 (H3K27me3) and regulates gene…”
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Journal Article -
5
Habitual physical activity improves outcomes among patients with myocardial infarction
Published in Frontiers in cardiovascular medicine (12-06-2023)“…This study evaluates the association between habitual physical activity (HPA) and the outcomes of patients with myocardial infarction (MI). Patients newly…”
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Journal Article -
6
SESN2 protects against doxorubicin-induced cardiomyopathy via rescuing mitophagy and improving mitochondrial function
Published in Journal of molecular and cellular cardiology (01-08-2019)“…The clinical application of doxorubicin (Dox) in cancer therapy is limited by its serious cardiotoxicity. Our previous studies and others have recognized that…”
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Journal Article -
7
miR-455-5p promotes pathological cardiac remodeling via suppression of PRMT1-mediated Notch signaling pathway
Published in Cellular and molecular life sciences : CMLS (01-12-2023)“…Pathological cardiac remodeling plays an essential role in the progression of cardiovascular diseases, and numerous microRNAs have been reported to participate…”
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Journal Article -
8
PEX5 prevents cardiomyocyte hypertrophy via suppressing the redox-sensitive signaling pathways MAPKs and STAT3
Published in European journal of pharmacology (05-09-2021)“…Peroxisomal biogenesis factor 5 (PEX5) is a member of peroxisome biogenesis protein family which serves as a shuttle receptor for the import of peroxisome…”
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Journal Article -
9
Elevated ITGA1 levels in type 2 diabetes: implications for cardiac function impairment
Published in Diabetologia (01-05-2024)“…Aims/hypothesis Type 2 diabetes mellitus is known to contribute to the development of heart failure with preserved ejection fraction (HFpEF). However,…”
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Journal Article -
10
Histone H4R3 symmetric di-methylation by Prmt5 protects against cardiac hypertrophy via regulation of Filip1L/β-catenin
Published in Pharmacological research (01-11-2020)“…[Display omitted] Although histone lysine methylation has been extensively studied for their participation in pathological cardiac hypertrophy, the potential…”
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Journal Article -
11
Sirtuin 1 represses PKC‐ζ activity through regulating interplay of acetylation and phosphorylation in cardiac hypertrophy
Published in British journal of pharmacology (01-02-2019)“…Background and Purpose Activation of PKC‐ζ is closely linked to the pathogenesis of cardiac hypertrophy. PKC‐ζ can be activated by certain lipid metabolites…”
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Journal Article -
12
Role of Cardiomyocyte-Derived Exosomal MicroRNA-146a-5p in Macrophage Polarization and Activation
Published in Disease markers (2022)“…Myocardial infarction arises from an excessive or prolonged inflammatory response, leading to ventricular remodeling or impaired cardiac function. Macrophages…”
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Journal Article -
13
High precision voltage-to-frequency converter
Published in Proceedings of 1994 37th Midwest Symposium on Circuits and Systems (1994)“…A bipolar high precision voltage-to-frequency converter is described. The circuit includes an input voltage-to-current conversion stage followed by…”
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Conference Proceeding -
14
Temperature-stable voltage to frequency converters
Published 01-01-1995“…An overview of voltage to frequency converters (VFCs) is given in this thesis. Comparing with charge-balance VFCs, multivibrator VFCs are more widely used in…”
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Dissertation