Search Results - "Cai, Sanjun"

Circular RNA ciRS-7-A Promising Prognostic Biomarker and a Potential Therapeutic Target in Colorectal Cancer by Weng, Wenhao, Wei, Qing, Toden, Shusuke, Yoshida, Kazuhiro, Nagasaka, Takeshi, Fujiwara, Toshiyoshi, Cai, Sanjun, Qin, Huanlong, Ma, Yanlei, Goel, Ajay

“…Colorectal cancer is one of the most common malignancies worldwide. Recently, a novel circular RNA, ciRS-7, was proposed to be a potential miR-7 sponge. As…”
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Fusobacterium nucleatum promotes chemoresistance to 5-fluorouracil by upregulation of BIRC3 expression in colorectal cancer by Zhang, Sheng, Yang, Yongzhi, Weng, Wenhao, Guo, Bomin, Cai, Guoxiang, Ma, Yanlei, Cai, Sanjun

“…Emerging evidence suggests a potential relationship between gut microbiota and the host response to chemotherapeutic drugs including 5-fluorouracil (5-Fu)…”
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Tumor-derived exosomal miR-934 induces macrophage M2 polarization to promote liver metastasis of colorectal cancer by Zhao, Senlin, Mi, Yushuai, Guan, Bingjie, Zheng, Binbin, Wei, Ping, Gu, Yanzi, Zhang, Zhengxiang, Cai, Sanjun, Xu, Ye, Li, Xinxiang, He, Xuefeng, Zhong, Xinyang, Li, Guichao, Chen, Zhiyu, Li, Dawei

“…Mounting evidence has demonstrated the vital importance of tumor-associated macrophages (TAMs) and exosomes in the formation of the premetastatic niche…”
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Patient-Derived Organoids Predict Chemoradiation Responses of Locally Advanced Rectal Cancer by Yao, Ye, Xu, Xiaoya, Yang, Lifeng, Zhu, Ji, Wan, Juefeng, Shen, Lijun, Xia, Fan, Fu, Guoxiang, Deng, Yun, Pan, Mengxue, Guo, Qiang, Gao, Xiaoxue, Li, Yuanchuang, Rao, Xinxin, Zhou, Yi, Liang, Liping, Wang, Yaqi, Zhang, Jing, Zhang, Hui, Li, Guichao, Zhang, Lixing, Peng, Junjie, Cai, Sanjun, Hu, Chen, Gao, Jianjun, Clevers, Hans, Zhang, Zhen, Hua, Guoqiang

“…Accumulating evidence indicates that patient-derived organoids (PDOs) can predict drug responses in the clinic, but the ability of PDOs to predict responses to…”
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Nomograms for predicting prognostic value of inflammatory biomarkers in colorectal cancer patients after radical resection by Li, Yaqi, Jia, Huixun, Yu, Wencheng, Xu, Ye, Li, Xinxiang, Li, Qingguo, Cai, Sanjun

“…Increasing evidence indicates that inflammation plays a vital role in tumorigenesis and progression. However, the prognostic value of inflammatory biomarkers…”
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Structural segregation of gut microbiota between colorectal cancer patients and healthy volunteers by Wang, Tingting, Cai, Guoxiang, Qiu, Yunping, Fei, Na, Zhang, Menghui, Pang, Xiaoyan, Jia, Wei, Cai, Sanjun, Zhao, Liping

“…Despite a long-suspected role in the development of human colorectal cancer (CRC), the composition of gut microbiota in CRC patients has not been adequately…”
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Prognostic impact of programed cell death-1 (PD-1) and PD-ligand 1 (PD-L1) expression in cancer cells and tumor infiltrating lymphocytes in colorectal cancer by Li, Yaqi, Liang, Lei, Dai, Weixing, Cai, Guoxiang, Xu, Ye, Li, Xinxiang, Li, Qingguo, Cai, Sanjun

“…Colorectal cancer (CRC) is 3rd most commonly diagnosed cancer in males and the second in females. PD-1/PD-L1 axis, as an immune checkpoint, is up-regulated in…”
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LncRNA MIR17HG promotes colorectal cancer liver metastasis by mediating a glycolysis-associated positive feedback circuit by Zhao, Senlin, Guan, Bingjie, Mi, Yushuai, Shi, Debing, Wei, Ping, Gu, Yanzi, Cai, Sanjun, Xu, Ye, Li, Xinxiang, Yan, Dongwang, Huang, Mingzhu, Li, Dawei

“…Glycolysis plays a crucial role in reprogramming the metastatic tumor microenvironment. A series of lncRNAs have been identified to function as oncogenic…”
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Apparent Diffusion Coefficient (ADC) value: a potential imaging biomarker that reflects the biological features of rectal cancer by Sun, Yiqun, Tong, Tong, Cai, Sanjun, Bi, Rui, Xin, Chao, Gu, Yajia

“…We elected to analyze the correlation between the pre-treatment apparent diffusion coefficient (ADC) and the clinical, histological, and immunohistochemical…”
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Highly‐metastatic colorectal cancer cell released miR‐181a‐5p‐rich extracellular vesicles promote liver metastasis by activating hepatic stellate cells and remodelling the tumour microenvironment by Zhao, Senlin, Mi, Yushuai, Zheng, Binbin, Wei, Ping, Gu, Yanzi, Zhang, Zhengxiang, Xu, Ye, Cai, Sanjun, Li, Xinxiang, Li, Dawei

“…Liver metastasis of colorectal cancer (CRLM) is the most common cause of CRC‐related mortality, and is typically caused by interactions between CRC cells and…”
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Utility of ctDNA in predicting response to neoadjuvant chemoradiotherapy and prognosis assessment in locally advanced rectal cancer: A prospective cohort study by Wang, Yaqi, Yang, Lifeng, Bao, Hua, Fan, Xiaojun, Xia, Fan, Wan, Juefeng, Shen, Lijun, Guan, Yun, Bao, Hairong, Wu, Xue, Xu, Yang, Shao, Yang, Sun, Yiqun, Tong, Tong, Li, Xinxiang, Xu, Ye, Cai, Sanjun, Zhu, Ji, Zhang, Zhen

“…Background For locally advanced rectal cancer (LARC) patients who receive neoadjuvant chemoradiotherapy (nCRT), there are no reliable indicators to accurately…”
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Circulating basophil count as a prognostic marker of tumor aggressiveness and survival outcomes in colorectal cancer by Liu, Qi, Luo, Dakui, Cai, Sanjun, Li, Qingguo, Li, Xinxiang

“…Background Accumulating evidence demonstrated immune/inflammation-related implications of basophils in affecting tissue microenvironment that surrounded a…”
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Long non-coding RNAs in Colorectal Cancer: Progression and Future Directions by Yang, Yongzhi, Junjie, Peng, Sanjun, Cai, Ma, Yanlei

“…Identification of the colorectal adenoma-carcinoma sequence with its corresponding genetic and epigenetic alterations has significantly increased our knowledge…”
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Antisense lncRNA LDLRAD4-AS1 promotes metastasis by decreasing the expression of LDLRAD4 and predicts a poor prognosis in colorectal cancer by Mo, Shaobo, Zhang, Long, Dai, Weixing, Han, Lingyu, Wang, Renjie, Xiang, Wenqiang, Wang, Zhimin, Li, Qingguo, Yu, Jun, Yuan, Jihang, Cai, Sanjun, Cai, Guoxiang

“…Long noncoding RNAs (lncRNAs) have been revealed to play critical roles in tumor initiation and progression. The antisense lncRNA LDLRAD4-AS1 is the longest…”
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Association between Fusobacterium nucleatum and colorectal cancer: Progress and future directions by Zhang, Sheng, Cai, Sanjun, Ma, Yanlei

“…The initiation and progression of colorectal cancer (CRC) involves genetic and epigenetic alterations influenced by dietary and environmental factors…”
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Organoid based personalized medicine: from bench to bedside by Li, Yaqi, Tang, Peiyuan, Cai, Sanjun, Peng, Junjie, Hua, Guoqiang

“…Three-dimensional cultured organoids have become a powerful in vitro research tool that preserves genetic, phenotypic and behavioral trait of in vivo organs,…”
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Postoperative circulating tumor DNA as markers of recurrence risk in stages II to III colorectal cancer by Chen, Gong, Peng, Junjie, Xiao, Qian, Wu, Hao-Xiang, Wu, Xiaojun, Wang, Fulong, Li, Liren, Ding, Peirong, Zhao, Qi, Li, Yaqi, Wang, Da, Shao, Yang, Bao, Hua, Pan, Zhizhong, Ding, Ke-Feng, Cai, Sanjun, Wang, Feng, Xu, Rui-Hua

“…Precise methods for postoperative risk stratification to guide the administration of adjuvant chemotherapy (ACT) in localized colorectal cancer (CRC) are still…”
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HER2 status is positively associated with vessel invasion of colorectal cancer: a retrospective large cohort study by Wang, Mingdian, Wang, Xiang, Li, Yiwei, Li, Qingguo, Cai, Sanjun, Li, Xinxiang, Ma, Maoguang

“…Purpose HER2-positive colorectal cancer was drawn increasing attention in recent years. Accumulating evidence showed HER2-positive metastatic colorectal cancer…”
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Aldolase B Overexpression is Associated with Poor Prognosis and Promotes Tumor Progression by Epithelial-Mesenchymal Transition in Colorectal Adenocarcinoma by Li, Qingguo, Li, Yaqi, Xu, Junyan, Wang, Sheng, Xu, Ye, Li, Xinxiang, Cai, Sanjun

“…Background: Glycolysis is considered to be the root of cancer development and progression, which involved a multi-step enzymatic reaction. Our study aimed at…”
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The FOXC1/FBP1 signaling axis promotes colorectal cancer proliferation by enhancing the Warburg effect by Li, Qingguo, Wei, Ping, Wu, Jitao, Zhang, Meng, Li, Guichao, Li, Yaqi, Xu, Ye, Li, Xinxiang, Xie, Dacheng, Cai, Sanjun, Xie, Keping, Li, Dawei

“…Aberrant expression of Forkhead box (FOX) transcription factors plays vital roles in carcinogenesis. However, the function of the FOX family member FOXC1 in…”
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