Search Results - "Cai, Qidong"

Identification of CNKSR1 as a biomarker for “cold” tumor microenvironment in lung adenocarcinoma: An integrative analysis based on a novel workflow by Cai, Qidong, Peng, Mou

“…Therapies targeting PD1/PD-L1 pathway have revolutionized the treatment of lung cancer. However, anti-PD1/PD-L1 therapies have proven beneficial for only a…”
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Bioinformatics construction and experimental validation of a cuproptosis-related lncRNA prognostic model in lung adenocarcinoma for immunotherapy response prediction by Li, Linfeng, Cai, Qidong, Wu, Zeyu, Li, Xizhe, Zhou, Wolong, Lu, Liqing, Yi, Bin, Chang, Ruimin, Zhang, Heng, Cheng, Yuanda, Zhang, Chunfang, Zhang, Junjie

“…Cuproptosis is a newly form of cell death. Cuproptosis related lncRNA in lung adenocarcinoma (LUAD) has also not been fully elucidated. In the present study,…”
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Exploration of predictive and prognostic alternative splicing signatures in lung adenocarcinoma using machine learning methods by Cai, Qidong, He, Boxue, Zhang, Pengfei, Zhao, Zhenyu, Peng, Xiong, Zhang, Yuqian, Xie, Hui, Wang, Xiang

“…Alternative splicing (AS) plays critical roles in generating protein diversity and complexity. Dysregulation of AS underlies the initiation and progression of…”
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Overexpression of LINC00551 promotes autophagy-dependent ferroptosis of lung adenocarcinoma via upregulating DDIT4 by sponging miR-4328 by Peng, Xiong, Yang, Rui, Peng, Weilin, Zhao, Zhenyu, Tu, Guangxu, He, Boxue, Cai, Qidong, Shi, Shuai, Yin, Wei, Yu, Fenglei, Tao, Yongguang, Wang, Xiang

“…According to mounting evidence, long noncoding RNAs (lncRNAs) play a vital role in regulated cell death (RCD). A potential strategy for cancer therapy involves…”
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A Novel Model Based on Genomic Instability-Associated Long Non-Coding RNAs for Predicting Prognosis and Response to Immunotherapy in Patients With Lung Adenocarcinoma by Tu, Guangxu, Peng, Weilin, Cai, Qidong, Zhao, Zhenyu, Peng, Xiong, He, Boxue, Zhang, Pengfei, Shi, Shuai, Wang, Xiang

“…Background: Emerging scientific evidence has shown that long non-coding RNAs (lncRNAs) exert critical roles in genomic instability (GI), which is considered a…”
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A Machine-Learning Approach to Developing a Predictive Signature Based on Transcriptome Profiling of Ground-Glass Opacities for Accurate Classification and Exploring the Immune Microenvironment of Early-Stage LUAD by Zhao, Zhenyu, Yin, Wei, Peng, Xiong, Cai, Qidong, He, Boxue, Shi, Shuai, Peng, Weilin, Tu, Guangxu, Li, Yunping, Li, Dateng, Tao, Yongguang, Peng, Muyun, Wang, Xiang, Yu, Fenglei

“…Screening for early-stage lung cancer with low-dose computed tomography is recommended for high-risk populations; consequently, the incidence of pure…”
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N6-Methyladenosine RNA Methylation Regulator-Related Alternative Splicing (AS) Gene Signature Predicts Non–Small Cell Lung Cancer Prognosis by Zhao, Zhenyu, Cai, Qidong, Zhang, Pengfei, He, Boxue, Peng, Xiong, Tu, Guangxu, Peng, Weilin, Wang, Li, Yu, Fenglei, Wang, Xiang

“…Aberrant N6-methyladenosine (m6A) RNA methylation regulatory genes and related gene alternative splicing (AS) could be used to predict the prognosis of…”
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Shared genetic aetiology of respiratory diseases: a genome-wide multitraits association analysis by Chen, Zhe, Gao, Ning, Wang, Xuanye, Chen, Xiangming, Zeng, YaQi, Li, Cong, Yang, Xiahong, Cai, Qidong, Wang, Xiang

“…ObjectiveThis study aims to explore the common genetic basis between respiratory diseases and to identify shared molecular and biological…”
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The NLRP11 Protein Bridges the Histone Lysine Acetyltransferase KAT7 to Acetylate Vimentin in the Early Stage of Lung Adenocarcinoma by Yang, Rui, Peng, Weilin, Shi, Shuai, Peng, Xiong, Cai, Qidong, Zhao, Zhenyu, He, Boxue, Tu, Guangxu, Yin, Wei, Chen, Yichuan, Zhang, Yuqian, Liu, Fang, Wang, Xiang, Xiao, Desheng, Tao, Yongguang

“…Accumulation of vimentin is the core event in epithelial–mesenchymal transition (EMT). Post‐translational modifications have been widely reported to play…”
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Whole-genome DNA methylation and DNA methylation-based biomarkers in lung squamous cell carcinoma by Cai, Qidong, He, Boxue, Tu, Guangxu, Peng, Weilin, Shi, Shuai, Qian, Banglun, Liang, Qingchun, Peng, Shaoliang, Tao, Yongguang, Wang, Xiang

“…Exploring early detection methods through comprehensive evaluation of DNA methylation for lung squamous cell carcinoma (LUSC) patients is of great…”
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Switched alternative splicing events as attractive features in lung squamous cell carcinoma by He, Boxue, Wei, Cong, Cai, Qidong, Zhang, Pengfei, Shi, Shuai, Peng, Xiong, Zhao, Zhenyu, Yin, Wei, Tu, Guangxu, Peng, Weilin, Tao, Yongguang, Wang, Xiang

“…Alternative splicing (AS) plays important roles in transcriptome and proteome diversity. Its dysregulation has a close affiliation with oncogenic processes…”
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Decreased IL-6 and NK Cells in Early-Stage Lung Adenocarcinoma Presenting as Ground-Glass Opacity by Zhang, Pengfei, He, Boxue, Cai, Qidong, Tu, Guangxu, Peng, Xiong, Zhao, Zhenyu, Peng, Weilin, Yu, Fenglei, Wang, Min, Tao, Yongguang, Wang, Xiang

“…Lung ground-glass opacities (GGOs) are an early manifestation of lung adenocarcinoma. It is of great value to study the changes in the immune microenvironment…”
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DNA methylome and transcriptome analysis established a model of four differentially methylated positions (DMPs) as a diagnostic marker in esophageal adenocarcinoma early detection by Peng, Weilin, Tu, Guangxu, Zhao, Zhenyu, He, Boxue, Cai, Qidong, Zhang, Pengfei, Peng, Xiong, Shi, Shuai, Wang, Xiang

“…Esophageal carcinogenesis involves in alterations of DNA methylation and gene transcription. This study profiled genomic DNA methylome vs. gene expression…”
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A model of twenty-three metabolic-related genes predicting overall survival for lung adenocarcinoma by Zhao, Zhenyu, He, Boxue, Cai, Qidong, Zhang, Pengfei, Peng, Xiong, Zhang, Yuqian, Xie, Hui, Wang, Xiang

“…The highest rate of cancer-related deaths worldwide is from lung adenocarcinoma (LUAD) annually. Metabolism was associated with tumorigenesis and cancer…”
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The top 100 most cited articles on bronchoscopy: a bibliometric analysis by He, Boxue, Zhang, Pengfei, Cai, Qidong, Shi, Shuai, Xie, Hui, Zhang, Yuqian, Peng, Xiong, Zhao, Zhenyu, Yin, Wei, Wang, Xiang

“…Abstract Background Bronchoscopy is applied broadly in the diagnosis and treatment of pulmonary diseases. Over the past few decades, an increasing number of…”
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Construction and validation of a 15-gene ferroptosis signature in lung adenocarcinoma by Tu, Guangxu, Peng, Weilin, Cai, Qidong, Zhao, Zhenyu, Peng, Xiong, He, Boxue, Zhang, Pengfei, Shi, Shuai, Tao, Yongguang, Wang, Xiang

“…Ferroptosis is a novel form of programmed cell death characterized by the excessive accumulation of intracellular iron and an increase in reactive oxygen…”
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Identification of a novel prognostic DNA methylation signature for lung adenocarcinoma based on consensus clustering method by Cai, Qidong, He, Boxue, Xie, Hui, Zhang, Pengfei, Peng, Xiong, Zhang, Yuqian, Zhao, Zhenyu, Wang, Xiang

“…Abnormal DNA methylation persists throughout carcinogenesis and cancer development. Hence, gene promoter methylation may act as a prognostic tool and provide…”
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Metagenomic analysis of the microbiome of lung adenocarcinoma with pure ground‐glass opacity by Zhao, Zhenyu, Qian, Banglun, Peng, Xiong, Yin, Wei, Cai, Qidong, Zhang, Pengfei, He, Boxue, Shi, Shuai, Peng, Weilin, Tu, Guangxu, Li, Yunping, Tao, Yongguang, Wang, Xiang, Yu, Fenglei

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miRNA-based biomarkers, therapies, and resistance in Cancer by He, Boxue, Zhao, Zhenyu, Cai, Qidong, Zhang, Yuqian, Zhang, Pengfei, Shi, Shuai, Xie, Hui, Peng, Xiong, Yin, Wei, Tao, Yongguang, Wang, Xiang

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miRNA-based biomarkers, therapies, and resistance in Cancer by He, Boxue, Zhao, Zhenyu, Cai, Qidong, Zhang, Yuqian, Zhang, Pengfei, Shi, Shuai, Xie, Hui, Peng, Xiong, Yin, Wei, Tao, Yongguang, Wang, Xiang

“…MicroRNAs (miRNAs), small non-coding RNAs (ncRNAs) of about 22 nucleotides in size, play important roles in gene regulation, and their dysregulation is…”
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